STRINGSTRING
CXCL13 CXCL13 HDAC5 HDAC5 TGFB1 TGFB1 CARD10 CARD10 CSNK2B CSNK2B THBS1 THBS1 TBXA2R TBXA2R SPRED1 SPRED1 ANGPT2 ANGPT2 DLL4 DLL4 KRIT1 KRIT1 NOTCH1 NOTCH1 DCN DCN ANGPT4 ANGPT4 LY6G5B LY6G5B PDCD10 PDCD10 DNAJA4 DNAJA4 BMP10 BMP10 DAB2IP DAB2IP JUP JUP ATP2B4 ATP2B4 MEF2C MEF2C ITGB1BP1 ITGB1BP1 SVBP SVBP ACVRL1 ACVRL1 PATZ1 PATZ1 GADD45A GADD45A SLIT2 SLIT2 VASH1 VASH1 LOC101092676 LOC101092676 SYNJ2BP SYNJ2BP MECP2 MECP2 TNF TNF ENSFCAP00000055099 ENSFCAP00000055099 MMRN2 MMRN2 HMGB1 HMGB1 APOH APOH STARD13 STARD13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCL13C-X-C motif chemokine. (120 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1152 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CARD10Caspase recruitment domain family member 10. (987 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
THBS1Thrombospondin 1. (1170 aa)
TBXA2RThromboxane A2 receptor. (392 aa)
SPRED1Sprouty related EVH1 domain containing 1. (443 aa)
ANGPT2Angiopoietin 2. (494 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
KRIT1KRIT1 ankyrin repeat containing. (736 aa)
NOTCH1Notch receptor 1. (2543 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
ANGPT4Angiopoietin 4. (499 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (216 aa)
PDCD10Programmed cell death 10. (212 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (489 aa)
BMP10TGF_BETA_2 domain-containing protein. (424 aa)
DAB2IPDAB2 interacting protein. (1166 aa)
JUPUncharacterized protein. (744 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1275 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (213 aa)
SVBPSmall vasohibin binding protein. (66 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha; Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). (165 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
VASH1Vasohibin 1. (446 aa)
LOC101092676TGF_BETA_2 domain-containing protein. (410 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa)
ENSFCAP00000055099Uncharacterized protein. (115 aa)
MMRN2Multimerin 2. (1005 aa)
HMGB1Uncharacterized protein. (233 aa)
APOHApolipoprotein H. (382 aa)
STARD13StAR related lipid transfer domain containing 13. (1127 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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