STRINGSTRING
MAD1L1 MAD1L1 EXOSC10 EXOSC10 LMOD1 LMOD1 NME6 NME6 PINK1 PINK1 SPTBN4 SPTBN4 TMOD1 TMOD1 IK IK PRELID1 PRELID1 CTC1 CTC1 LRRK2 LRRK2 CAMSAP1 CAMSAP1 FBXO43 FBXO43 DCP2 DCP2 CCNF CCNF NAT10 NAT10 KAT2A KAT2A VILL VILL ANKRD27 ANKRD27 VIL1 VIL1 KATNB1 KATNB1 PICK1 PICK1 PARL PARL SPTB SPTB CAPG CAPG CORO1B CORO1B TTBK2 TTBK2 SWAP70 SWAP70 PRKCD PRKCD ERCC4 ERCC4 PFN4 PFN4 KAT2B KAT2B MID1IP1 MID1IP1 PINX1 PINX1 CAMSAP2 CAMSAP2 PPFIA1 PPFIA1 SCIN SCIN XRCC1 XRCC1 TMOD4 TMOD4 PSMG2 PSMG2 DEF6 DEF6 KLHL22 KLHL22 HIP1R HIP1R DMRT1 DMRT1 HUWE1 HUWE1 SLC25A5 SLC25A5 SLC25A31 SLC25A31 CAPZA3 CAPZA3 RBM14 RBM14 SPTBN2 SPTBN2 ADCK5 ADCK5 MAPRE1 MAPRE1 WASF2 WASF2 MKKS MKKS GNL3L GNL3L LMOD3 LMOD3 KNTC1 KNTC1 ACD ACD LIMA1 LIMA1 TRIP13 TRIP13 TOP2A TOP2A CKAP2 CKAP2 PIK3R1 PIK3R1 TM6SF1 TM6SF1 PIF1 PIF1 KIF24 KIF24 LMNA LMNA SLX4 SLX4 NUPR1 NUPR1 GDI2 GDI2 BAZ1B BAZ1B TMEM67 TMEM67 PLK1 PLK1 BECN1 BECN1 VAT1 VAT1 CAPZA1 CAPZA1 PLEKHH2 PLEKHH2 RAD21 RAD21 TBCD TBCD TBC1D7 TBC1D7 AVIL AVIL RHPN2 RHPN2 BUB1 BUB1 CHEK1 CHEK1 CDH5-2 CDH5-2 ARHGAP28 ARHGAP28 ARFGEF1 ARFGEF1 WAS WAS CGNL1 CGNL1 RAD50 RAD50 PAK2 PAK2 CORO2A CORO2A BUB3 BUB3 ATRX ATRX M3WWT0_FELCA M3WWT0_FELCA TTK TTK MYADM MYADM TWF2 TWF2 TESK1 TESK1 SSH1 SSH1 SEC22B SEC22B TERF2IP TERF2IP H3F3A H3F3A MTM1 MTM1 KANK4 KANK4 PHF23 PHF23 SPTBN5 SPTBN5 POT1 POT1 PSMD10 PSMD10 HASPIN HASPIN STYXL1 STYXL1 CAPZA2 CAPZA2 FXN FXN FBXO5 FBXO5 SMG6 SMG6 MDM1 MDM1 NANOS2 NANOS2 CIB1 CIB1 ADD2 ADD2 AFMID AFMID ADD1 ADD1 SMCR8 SMCR8 M3XE36_FELCA M3XE36_FELCA PPIF PPIF SLC35F6 SLC35F6 TMEM14A TMEM14A ATM ATM GHITM GHITM ODF2L ODF2L ENSFCAP00000027627 ENSFCAP00000027627 AVP AVP TNKS TNKS RAD1 RAD1 ENSFCAP00000029374 ENSFCAP00000029374 OMA1 OMA1 SPTAN1 SPTAN1 TMEFF2 TMEFF2 FKBP4 FKBP4 MCM2 MCM2 CAV3 CAV3 SMAD4 SMAD4 SPTBN1 SPTBN1 MAD2L1 MAD2L1 ATXN7L1 ATXN7L1 MYOC MYOC TWF1 TWF1 RDX RDX BBS4 BBS4 NBDY NBDY ARHGEF2 ARHGEF2 HGF HGF WDR63 WDR63 TFRC TFRC STMN2 STMN2 ENSFCAP00000034093 ENSFCAP00000034093 CHMP4A CHMP4A CDK10 CDK10 LIF LIF SLC25A4 SLC25A4 TERF2 TERF2 PRRT2 PRRT2 WAPL WAPL ENSFCAP00000037485 ENSFCAP00000037485 PIK3CA PIK3CA ADCK1 ADCK1 MAK MAK TOM1L2 TOM1L2 BIRC5 BIRC5 ENSFCAP00000038408 ENSFCAP00000038408 CORO1A CORO1A HDGFL3 HDGFL3 PHLDB2 PHLDB2 CCP110 CCP110 APC APC EML2 EML2 ZNF207 ZNF207 GAS2L2 GAS2L2 RNF41 RNF41 FLII FLII SLIT2 SLIT2 SPTA1 SPTA1 ERCC1 ERCC1 SRC SRC FAM49B FAM49B APC2 APC2 LOC102901344 LOC102901344 GMFB GMFB ATXN7 ATXN7 IGF1 IGF1 TPR TPR CAPZB CAPZB FLCN FLCN DYRK1A DYRK1A FEZ2 FEZ2 PFN2 PFN2 EPS8 EPS8 PRKN PRKN F11R F11R SMARCA5 SMARCA5 ENSFCAP00000044477 ENSFCAP00000044477 ENSFCAP00000044600 ENSFCAP00000044600 TOM1L1 TOM1L1 HDAC6 HDAC6 ENSFCAP00000045292 ENSFCAP00000045292 SSH2 SSH2 MPHOSPH9 MPHOSPH9 TP53 TP53 CDH5 CDH5 ADD3 ADD3 ENSFCAP00000046486 ENSFCAP00000046486 ARHGEF18 ARHGEF18 TBC1D30 TBC1D30 GALK1 GALK1 TINF2 TINF2 CDK5RAP2 CDK5RAP2 TNKS2 TNKS2 ENSFCAP00000047489 ENSFCAP00000047489 DMTN DMTN NAV3 NAV3 ARAP1 ARAP1 ACAA2 ACAA2 SLC25A6 SLC25A6 CAMSAP3 CAMSAP3 OPA1 OPA1 MNAT1 MNAT1 ASB15 ASB15 YAP1 YAP1 TIGAR TIGAR ARHGAP6 ARHGAP6 TSPO TSPO BMP4 BMP4 TMSB10 TMSB10 EVI5L EVI5L LOC111559734 LOC111559734 NBN NBN TMOD2 TMOD2 FEZ1 FEZ1 AURKB AURKB CLIP3 CLIP3 BMERB1 BMERB1 ENSFCAP00000053448 ENSFCAP00000053448 GSN GSN MTBP MTBP HNRNPU HNRNPU NUBP1 NUBP1 SCFD1 SCFD1 PTTG1 PTTG1 SPDL1 SPDL1 SSH3 SSH3 LOC111558717 LOC111558717 ENSFCAP00000056200 ENSFCAP00000056200 GMFG GMFG RHPN1 RHPN1 TMEM39A TMEM39A BOK BOK ENSFCAP00000057249 ENSFCAP00000057249 BUB1B BUB1B LIMK2 LIMK2 MPV17L MPV17L ATXN7L2 ATXN7L2 ENSFCAP00000059017 ENSFCAP00000059017 TMEM39B TMEM39B CEP97 CEP97 TACC3 TACC3 MAP6D1 MAP6D1 BAK1 BAK1 SVIL SVIL MUL1 MUL1 KANK3 KANK3 CCDC84 CCDC84 INPP5K INPP5K TMPRSS5 TMPRSS5 KANK1 KANK1 NOL3 NOL3 MET MET SKA2 SKA2 ENSFCAP00000061110 ENSFCAP00000061110 CORO2B CORO2B ZWILCH ZWILCH HORMAD1 HORMAD1 EHMT2 EHMT2 BNIP3 BNIP3 SPEF1 SPEF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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MAD1L1Mitotic arrest deficient 1 like 1. (916 aa)
EXOSC10Exosome component 10. (887 aa)
LMOD1Leiomodin 1. (579 aa)
NME6Nucleoside diphosphate kinase. (193 aa)
PINK1PTEN induced kinase 1. (581 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2568 aa)
TMOD1Tropomodulin 1. (346 aa)
IKIK cytokine. (555 aa)
PRELID1PRELI domain containing 1. (219 aa)
CTC1CST telomere replication complex component 1. (1218 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CAMSAP1Calmodulin regulated spectrin associated protein 1. (1507 aa)
FBXO43F-box protein 43. (700 aa)
DCP2Decapping mRNA 2. (422 aa)
CCNFCyclin F; Belongs to the cyclin family. (848 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (836 aa)
VILLVillin like. (855 aa)
ANKRD27Ankyrin repeat domain 27. (1050 aa)
VIL1Villin 1. (827 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
PARLRhomboid domain-containing protein. (379 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2326 aa)
CAPGCapping actin protein, gelsolin like. (388 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (488 aa)
TTBK2Tau tubulin kinase 2. (1252 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
MID1IP1MID1 interacting protein 1. (183 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (312 aa)
CAMSAP2Calmodulin regulated spectrin associated protein family member 2. (1490 aa)
PPFIA1PTPRF interacting protein alpha 1. (1069 aa)
SCINScinderin. (715 aa)
XRCC1X-ray repair cross complementing 1. (631 aa)
TMOD4Tropomodulin 4. (345 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (266 aa)
DEF6DEF6 guanine nucleotide exchange factor. (631 aa)
KLHL22Kelch like family member 22. (634 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (378 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4374 aa)
SLC25A5Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
RBM14RNA binding motif protein 14. (669 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2418 aa)
ADCK5AarF domain containing kinase 5. (580 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
WASF2WASP family member 2. (498 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
GNL3LG protein nucleolar 3 like. (708 aa)
LMOD3Leiomodin 3. (577 aa)
KNTC1Kinetochore associated 1. (2207 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (453 aa)
LIMA1LIM domain and actin binding 1. (780 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (432 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1534 aa)
CKAP2CKAP2_C domain-containing protein. (682 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
TM6SF1Transmembrane 6 superfamily member 1. (370 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (641 aa)
KIF24Kinesin family member 24; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1427 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (664 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1742 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
GDI2Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (445 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1482 aa)
TMEM67Transmembrane protein 67. (994 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
BECN1Beclin 1. (448 aa)
VAT1Vesicle amine transport 1. (391 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1492 aa)
RAD21RAD21 cohesin complex component. (631 aa)
TBCDTubulin folding cofactor D. (1189 aa)
TBC1D7TBC1 domain family member 7. (293 aa)
AVILAdvillin. (816 aa)
RHPN2Rhophilin Rho GTPase binding protein 2. (686 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1086 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
CDH5-2Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (314 aa)
ARHGAP28Rho GTPase activating protein 28. (729 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
WASWASP actin nucleation promoting factor. (501 aa)
CGNL1Cingulin like 1. (1293 aa)
RAD50Zinc-hook domain-containing protein. (1311 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CORO2ACoronin; Belongs to the WD repeat coronin family. (515 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
ATRXATRX chromatin remodeler. (2486 aa)
M3WWT0_FELCARhomboid domain-containing protein. (188 aa)
TTKTTK protein kinase. (856 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
SSH1Slingshot protein phosphatase 1. (1051 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa)
TERF2IPTERF2 interacting protein. (406 aa)
H3F3AHistone H3; Belongs to the histone H3 family. (136 aa)
MTM1Myotubularin 1. (603 aa)
KANK4KN motif and ankyrin repeat domains 4. (1013 aa)
PHF23PHD finger protein 23. (403 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3515 aa)
POT1Protection of telomeres 1. (785 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
HASPINHistone H3 associated protein kinase. (782 aa)
STYXL1Serine/threonine/tyrosine interacting like 1. (311 aa)
CAPZA2F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (394 aa)
FXNFrataxin. (211 aa)
FBXO5F-box protein 5. (451 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1413 aa)
MDM1Mdm1 nuclear protein. (729 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (138 aa)
CIB1Calcium and integrin binding 1. (191 aa)
ADD2Adducin 2. (723 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (306 aa)
ADD1Adducin 1. (761 aa)
SMCR8SMCR8-C9orf72 complex subunit. (938 aa)
M3XE36_FELCAUncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (243 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (204 aa)
SLC35F6Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter. (371 aa)
TMEM14ATransmembrane protein 14A. (209 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
GHITMGrowth hormone inducible transmembrane protein; Belongs to the BI1 family. (345 aa)
ODF2LOuter dense fiber of sperm tails 2 like. (607 aa)
ENSFCAP00000027627CKAP2_C domain-containing protein. (640 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (166 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
RAD1RAD1 checkpoint DNA exonuclease. (281 aa)
ENSFCAP00000029374F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (162 aa)
OMA1OMA1 zinc metallopeptidase. (527 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2725 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (394 aa)
FKBP4Peptidylprolyl isomerase. (464 aa)
MCM2DNA helicase; Belongs to the MCM family. (929 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (221 aa)
ATXN7L1Ataxin 7 like 1. (959 aa)
MYOCMyocilin, C-terminal fragment; Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. [...] (498 aa)
TWF1Twinfilin actin binding protein 1. (357 aa)
RDXRadixin. (604 aa)
BBS4Bardet-Biedl syndrome 4. (525 aa)
NBDYNegative regulator of P-body association. (68 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1181 aa)
HGFHepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). (728 aa)
WDR63WD repeat domain 63. (908 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] (789 aa)
STMN2Stathmin 2. (202 aa)
ENSFCAP00000034093Uncharacterized protein; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (88 aa)
CHMP4ACharged multivesicular body protein 4A. (220 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (441 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
PRRT2Proline rich transmembrane protein 2. (362 aa)
WAPLWAPL cohesin release factor. (1196 aa)
ENSFCAP00000037485Uncharacterized protein. (183 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ADCK1AarF domain containing kinase 1. (523 aa)
MAKMale germ cell associated kinase. (656 aa)
TOM1L2Target of myb1 like 2 membrane trafficking protein. (551 aa)
BIRC5Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] (142 aa)
ENSFCAP00000038408Uncharacterized protein. (249 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (655 aa)
HDGFL3HDGF like 3. (203 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1247 aa)
CCP110Centriolar coiled-coil protein 110. (1009 aa)
APCAPC regulator of WNT signaling pathway. (2874 aa)
EML2EMAP like 2. (849 aa)
ZNF207Zinc finger protein 207. (538 aa)
GAS2L2Growth arrest specific 2 like 2. (879 aa)
RNF41Ring finger protein 41. (317 aa)
FLIIFLII actin remodeling protein. (1276 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (329 aa)
SRCTyrosine-protein kinase. (678 aa)
FAM49BFamily with sequence similarity 49 member B. (378 aa)
APC2APC regulator of WNT signaling pathway 2. (2289 aa)
LOC102901344Uncharacterized protein. (226 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (143 aa)
ATXN7Ataxin 7. (946 aa)
IGF1Insulin like growth factor 1. (195 aa)
TPRTranslocated promoter region, nuclear basket protein. (2498 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
FLCNUncharacterized protein. (579 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
FEZ2Fasciculation and elongation protein zeta 2. (383 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (821 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
F11RJunctional adhesion molecule A; Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation. (Microbial infection) In case of orthoreovirus infection, serves as rec [...] (378 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1052 aa)
ENSFCAP00000044477Uncharacterized protein. (43 aa)
ENSFCAP00000044600Uncharacterized protein. (66 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein. (521 aa)
HDAC6Histone deacetylase 6. (1178 aa)
ENSFCAP00000045292CH_2 domain-containing protein. (564 aa)
SSH2Slingshot protein phosphatase 2. (1435 aa)
MPHOSPH9M-phase phosphoprotein 9. (1181 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
CDH5Uncharacterized protein. (402 aa)
ADD3Adducin 3. (706 aa)
ENSFCAP00000046486Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
ARHGEF18Uncharacterized protein. (1357 aa)
TBC1D30TBC1 domain family member 30. (717 aa)
GALK1Galactokinase 1. (619 aa)
TINF2TERF1 interacting nuclear factor 2. (466 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1856 aa)
TNKS2Poly [ADP-ribose] polymerase. (1344 aa)
ENSFCAP00000047489Uncharacterized protein; Belongs to the BI1 family. (200 aa)
DMTNDematin actin binding protein. (405 aa)
NAV3Neuron navigator 3. (2385 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1455 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
SLC25A6Solute carrier family 25 member 6; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1218 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
ASB15Ankyrin repeat and SOCS box containing 15. (597 aa)
YAP1Yes associated protein 1. (498 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (428 aa)
ARHGAP6Rho GTPase activating protein 6. (455 aa)
TSPOUncharacterized protein. (257 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
EVI5LEcotropic viral integration site 5 like. (865 aa)
LOC111559734Bone morphogenetic protein 7. (426 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (783 aa)
TMOD2Tropomodulin 3. (440 aa)
FEZ1Fasciculation and elongation protein zeta 1. (439 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (408 aa)
CLIP3CAP-Gly domain containing linker protein 3. (571 aa)
BMERB1BMERB domain containing 1. (204 aa)
ENSFCAP00000053448Uncharacterized protein. (182 aa)
GSNGelsolin. (815 aa)
MTBPMDM2 binding protein. (911 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (899 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (644 aa)
PTTG1Uncharacterized protein. (213 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (621 aa)
SSH3Slingshot protein phosphatase 3. (663 aa)
LOC111558717Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (317 aa)
ENSFCAP00000056200MOEP19 domain-containing protein. (399 aa)
GMFGGlia maturation factor gamma. (195 aa)
RHPN1Rhophilin Rho GTPase binding protein 1. (760 aa)
TMEM39ATransmembrane protein 39A. (505 aa)
BOKBCL2 family apoptosis regulator BOK. (320 aa)
ENSFCAP00000057249Uncharacterized protein. (57 aa)
BUB1BBUB1 mitotic checkpoint serine/threonine kinase B. (1062 aa)
LIMK2LIM domain kinase 2. (711 aa)
MPV17LUncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (300 aa)
ATXN7L2Ataxin 7 like 2. (779 aa)
ENSFCAP00000059017Uncharacterized protein. (73 aa)
TMEM39BTransmembrane protein 39B. (512 aa)
CEP97Centrosomal protein 97. (1021 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (806 aa)
MAP6D1MAP6 domain containing 1. (254 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
SVILSupervillin. (2361 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (568 aa)
KANK3KN motif and ankyrin repeat domains 3. (862 aa)
CCDC84Coiled-coil domain containing 84. (437 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (525 aa)
TMPRSS5Zw10 kinetochore protein. (848 aa)
KANK1KN motif and ankyrin repeat domains 1. (1366 aa)
NOL3Nucleolar protein 3. (218 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1382 aa)
SKA2Tripartite motif containing 37. (987 aa)
ENSFCAP00000061110TGF_BETA_2 domain-containing protein. (362 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (501 aa)
ZWILCHZwilch kinetochore protein. (630 aa)
HORMAD1HORMA domain containing 1. (413 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1407 aa)
BNIP3BCL2 interacting protein 3. (187 aa)
SPEF1Sperm flagellar 1. (343 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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