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PLN PLN DHRS7C DHRS7C CHD7 CHD7 CALM2 CALM2 M3WQU5_FELCA M3WQU5_FELCA TMEM38B TMEM38B TMEM38A TMEM38A CASQ2 CASQ2 CALML3 CALML3 LOC101097703 LOC101097703 ENSFCAP00000029012 ENSFCAP00000029012 CASQ1 CASQ1 FKBP1B FKBP1B CALM1 CALM1 RYR2 RYR2 CLIC2 CLIC2 CALM3 CALM3 HRC HRC TRDN TRDN ENSFCAP00000060347 ENSFCAP00000060347
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
CALM2Calmodulin 2; Belongs to the calmodulin family. (149 aa)
M3WQU5_FELCAEF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa)
TMEM38BTransmembrane protein 38B. (409 aa)
TMEM38ATransmembrane protein 38A. (381 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
LOC101097703EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa)
ENSFCAP00000029012Uncharacterized protein; Belongs to the calmodulin family. (124 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (494 aa)
FKBP1BPeptidylprolyl isomerase. (238 aa)
CALM1Uncharacterized protein; Belongs to the calmodulin family. (192 aa)
RYR2Ryanodine receptor 2. (4967 aa)
CLIC2Chloride intracellular channel 2. (284 aa)
CALM3Calmodulin 3; Belongs to the calmodulin family. (276 aa)
HRCHistidine rich calcium binding protein. (788 aa)
TRDNTriadin. (721 aa)
ENSFCAP00000060347Uncharacterized protein; Belongs to the calmodulin family. (146 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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