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| | TEX264 | Testis expressed 264, ER-phagy receptor. (313 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) |
| | UFL1 | UFM1 specific ligase 1. (792 aa) |
| | CTSD | Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (408 aa) |
| | EMC6 | ER membrane protein complex subunit 6. (110 aa) |
| | SNAPIN | SNAP associated protein. (229 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) |
| | UFC1 | Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1161 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1593 aa) |
| | ULK1 | Unc-51 like autophagy activating kinase 1. (1113 aa) |
| | RETREG2 | Reticulophagy regulator family member 2. (546 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (998 aa) |
| | ATG16L1 | Autophagy related 16 like 1. (623 aa) |
| | RETREG3 | Reticulophagy regulator family member 3. (466 aa) |
| | PATL2 | SPG11 vesicle trafficking associated, spatacsin. (2444 aa) |
| | ATG2A | Autophagy related 2A. (1928 aa) |
| | BECN1 | Beclin 1. (448 aa) |
| | ATG9B | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (920 aa) |
| | HMOX1 | Heme oxygenase 1. (404 aa) |
| | UBXN2B | UBX domain protein 2B. (440 aa) |
| | RUFY4 | RUN and FYVE domain containing 4. (697 aa) |
| | CALCOCO2 | Calcium binding and coiled-coil domain 2. (474 aa) |
| | KIAA1324 | KIAA1324. (1091 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (578 aa) |
| | ENSFCAP00000059015 | Uncharacterized protein. (263 aa) |
| | UBXN2A | UBX domain protein 2A. (265 aa) |
| | WIPI1 | WD repeat domain, phosphoinositide interacting 1. (470 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa) |
| | MCOLN1 | Mucolipin 1. (620 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (468 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (956 aa) |
| | SNX7 | Sorting nexin 7. (513 aa) |
| | UVRAG | UV radiation resistance associated. (718 aa) |
| | TECPR1 | Tectonin beta-propeller repeat containing 1. (1201 aa) |
| | HDAC10 | Histone deacetylase 10. (546 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (456 aa) |
| | VTI1B | Vesicle transport through interaction with t-SNAREs 1B. (247 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (492 aa) |
| | MAP1LC3B | Uncharacterized protein. (309 aa) |
| | GAA | Glucosidase alpha, acid; Belongs to the glycosyl hydrolase 31 family. (1002 aa) |
| | NSFL1C | NSFL1 cofactor. (470 aa) |
| | RUBCNL | Rubicon like autophagy enhancer. (677 aa) |
| | EPG5 | Ectopic P-granules autophagy protein 5 homolog. (2616 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (263 aa) |
| | RAB1A | RAB1A, member RAS oncogene family. (238 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa) |
| | TMEM41B | Transmembrane protein 41B. (291 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (428 aa) |
| | GABARAPL1 | GABA type A receptor associated protein like 1. (151 aa) |
| | UBXN6 | UBX domain protein 6. (502 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (372 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (227 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | ATG3 | Autophagy-related protein 3. (333 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa) |
| | ENSFCAP00000044926 | Uncharacterized protein. (107 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa) |
| | SPATA33 | Uncharacterized protein. (96 aa) |
| | LGALS8 | Galectin. (376 aa) |
| | ENSFCAP00000041779 | Uncharacterized protein. (112 aa) |
| | ATG16L2 | Autophagy related 16 like 2. (617 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa) |
| | MAP1LC3C | Uncharacterized protein. (141 aa) |
| | ARFIP2 | ADP ribosylation factor interacting protein 2. (374 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (221 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (954 aa) |
| | EI24 | Uncharacterized protein. (340 aa) |
| | VAMP8 | Vesicle associated membrane protein 8. (99 aa) |
| | ENSFCAP00000038726 | Uncharacterized protein. (134 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (752 aa) |
| | MFSD8 | Major facilitator superfamily domain containing 8. (522 aa) |
| | ATG101 | Autophagy related 101. (344 aa) |
| | PRAF2 | WD repeat domain 45. (361 aa) |
| | RAB33B | Uncharacterized protein. (488 aa) |
| | ENSFCAP00000034738 | Uncharacterized protein. (249 aa) |
| | RAB1B | RAB1B, member RAS oncogene family. (201 aa) |
| | LOC101095070 | Uncharacterized protein. (141 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | CHMP4A | Charged multivesicular body protein 4A. (220 aa) |
| | CHMP1A | Charged multivesicular body protein 1A. (196 aa) |
| | VTI1A | Vesicle transport through interaction with t-SNAREs 1A. (267 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1066 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (421 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (968 aa) |
| | CLN3 | Battenin. (438 aa) |
| | LIX1 | Uncharacterized protein. (314 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | ATG10 | Autophagy related 10. (353 aa) |
| | LIX1L | Limb and CNS expressed 1 like. (336 aa) |
| | MFN2 | Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | UBA5 | Ubiquitin like modifier activating enzyme 5. (404 aa) |
| | PLAA | Phospholipase A2 activating protein. (796 aa) |
| | TRAPPC8 | Trafficking protein particle complex 8. (1435 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (237 aa) |
| | ATP2A2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytos [...] (1006 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) |
| | WDR81 | WD repeat domain 81. (1943 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2540 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | STX12 | Syntaxin 12; Belongs to the syntaxin family. (274 aa) |
| | DDRGK1 | DDRGK domain containing 1. (340 aa) |
| | MTM1 | Myotubularin 1. (603 aa) |
| | AP4M1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (460 aa) |
| | TMEM74 | Transmembrane protein 74. (305 aa) |
| | STBD1 | Starch binding domain 1. (361 aa) |
| | PACS2 | Phosphofurin acidic cluster sorting protein 2. (902 aa) |
| | ATG14 | Autophagy related 14. (510 aa) |
| | RAB7A | Uncharacterized protein. (207 aa) |
| | VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (596 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (239 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | M3WPJ7_FELCA | Uncharacterized protein. (188 aa) |
| | PJVK | Pejvakin. (352 aa) |
| | STX17 | Syntaxin 17; Belongs to the syntaxin family. (302 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (757 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (790 aa) |
| | SQSTM1 | Sequestosome 1. (443 aa) |
| | ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1301 aa) |
| | LOC101094500 | Uncharacterized protein. (274 aa) |
| | ATG2B | Autophagy related 2B. (2114 aa) |
| | SNX30 | Sorting nexin family member 30. (449 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (761 aa) |
| | STING1 | Stimulator of interferon genes. (377 aa) |
| | SNX14 | Sorting nexin 14. (1004 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | WDR45B | WD repeat domain 45B. (344 aa) |
| | WDFY3 | WD repeat and FYVE domain containing 3. (3527 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | VMP1 | Vacuole membrane protein 1. (406 aa) |
| | ULK3 | Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (470 aa) |
