STRINGSTRING
JMJD8 JMJD8 RAB3GAP2 RAB3GAP2 MAPK3 MAPK3 TSC2 TSC2 PIP4K2A PIP4K2A SIRT1 SIRT1 PAFAH1B2 PAFAH1B2 TRIM13 TRIM13 SMCR8 SMCR8 SH3GLB1 SH3GLB1 SNX18 SNX18 LRSAM1 LRSAM1 DCN DCN RALB RALB BAG3 BAG3 WAC WAC RIPK2 RIPK2 AMBRA1 AMBRA1 ATG2A ATG2A SUPT5H SUPT5H KDR KDR NOD2 NOD2 ADRB2 ADRB2 PINK1 PINK1 HIF1A HIF1A VPS13D VPS13D HTT HTT SPTLC1 SPTLC1 SNX4 SNX4 HMOX1 HMOX1 RUFY4 RUFY4 BNIP3 BNIP3 CALCOCO2 CALCOCO2 PIP4K2C PIP4K2C SPTLC2 SPTLC2 WIPI1 WIPI1 RNF31 RNF31 SNX7 SNX7 SESN2 SESN2 TBK1 TBK1 FYCO1 FYCO1 SESN3 SESN3 RAB3GAP1 RAB3GAP1 PIP4K2B PIP4K2B SCOC SCOC SESN1 SESN1 STING1 STING1 CD4H9orf72 CD4H9orf72 IL4 IL4 SNX30 SNX30 LARP1 LARP1 NOD1 NOD1 PRAF2 PRAF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JMJD8WD repeat domain 24. (790 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1393 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TSC2TSC complex subunit 2. (1806 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (421 aa)
SIRT1Sirtuin 1. (745 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
TRIM13Tripartite motif containing 13. (409 aa)
SMCR8SMCR8-C9orf72 complex subunit. (938 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (401 aa)
SNX18Sorting nexin. (624 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (728 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
RALBRAS like proto-oncogene B. (206 aa)
BAG3BCL2 associated athanogene 3. (565 aa)
WACWW domain containing adaptor with coiled-coil. (646 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)
ATG2AAutophagy related 2A. (1928 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1014 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
PINK1PTEN induced kinase 1. (581 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4389 aa)
HTTHuntingtin. (3140 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (473 aa)
SNX4Sorting nexin 4. (459 aa)
HMOX1Heme oxygenase 1. (404 aa)
RUFY4RUN and FYVE domain containing 4. (697 aa)
BNIP3BCL2 interacting protein 3. (187 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (474 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (435 aa)
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (694 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (470 aa)
RNF31Uncharacterized protein. (1081 aa)
SNX7Sorting nexin 7. (513 aa)
SESN2Sestrin 2. (516 aa)
TBK1TANK binding kinase 1. (729 aa)
FYCO1FYVE and coiled-coil domain containing 1. (1459 aa)
SESN3Sestrin 3. (492 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (1028 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
SCOCShort coiled-coil protein. (175 aa)
SESN1Sestrin 1. (551 aa)
STING1Stimulator of interferon genes. (377 aa)
CD4H9orf72Chromosome D4 C9orf72 homolog. (481 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa)
SNX30Sorting nexin family member 30. (449 aa)
LARP1La ribonucleoprotein domain family member 1. (1102 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
PRAF2WD repeat domain 45. (361 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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