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CCNY CCNY CCNO CCNO CCNJL CCNJL HEXIM2 HEXIM2 CCNE2 CCNE2 CDKN1A CDKN1A CDKN2D CDKN2D CCNG2 CCNG2 SOWAHB SOWAHB CCNA2 CCNA2 CCNG1 CCNG1 CCNJ CCNJ CCNYL1 CCNYL1 CKS2 CKS2 CNTD2 CNTD2 CCNB2 CCNB2 CDK5R1 CDK5R1 HEXIM1 HEXIM1 CCNT1 CCNT1 GPRC5C GPRC5C CDKN1B CDKN1B CDKN1C CDKN1C CDK5R2 CDK5R2 CCND2 CCND2 CCNK CCNK ENSFCAP00000041398 ENSFCAP00000041398 CCND3 CCND3 CCNB1 CCNB1 ENSFCAP00000037196 ENSFCAP00000037196 ENSFCAP00000048496 ENSFCAP00000048496 MNAT1 MNAT1 CCNQ CCNQ CCNF CCNF CCNE1 CCNE1 KAT2B KAT2B CCND1 CCND1 INCA1 INCA1 CCNL2 CCNL2 CCNI CCNI CCNL1 CCNL1 CCNT2 CCNT2 CCNH CCNH ENSFCAP00000061217 ENSFCAP00000061217 CCNA1 CCNA1 CCNC CCNC CASP3 CASP3 CDKN2C CDKN2C CKS1B CKS1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
CCNOCyclin O; Belongs to the cyclin family. (351 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (388 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (292 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (406 aa)
CDKN1ACyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (343 aa)
SOWAHBSosondowah ankyrin repeat domain family member B. (782 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
CCNJCyclin J; Belongs to the cyclin family. (383 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (363 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (192 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (397 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
CCNT1CYCLIN domain-containing protein; Belongs to the cyclin family. (184 aa)
GPRC5CG protein-coupled receptor class C group 5 member C. (486 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (264 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (370 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
CCNKCyclin K; Belongs to the cyclin family. (582 aa)
ENSFCAP00000041398CYCLIN domain-containing protein; Belongs to the cyclin family. (263 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (600 aa)
ENSFCAP00000037196Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (56 aa)
ENSFCAP00000048496Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (62 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCNQCyclin Q; Belongs to the cyclin family. (376 aa)
CCNFCyclin F; Belongs to the cyclin family. (848 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (312 aa)
INCA1Inhibitor of CDK, cyclin A1 interacting protein 1. (256 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (565 aa)
CCNICyclin I; Belongs to the cyclin family. (380 aa)
CCNL1Cyclin L1; Belongs to the cyclin family. (557 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (742 aa)
CCNHCyclin H; Belongs to the cyclin family. (326 aa)
ENSFCAP00000061217Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (247 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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