STRINGSTRING
CCNO CCNO CCNE1 CCNE1 CCNF CCNF CCNQ CCNQ KAT2B KAT2B CCNA1 CCNA1 HEXIM1 HEXIM1 CDK5R1 CDK5R1 CCNB2 CCNB2 CNTD2 CNTD2 CKS2 CKS2 CCNYL1 CCNYL1 CCNJ CCNJ CCNG1 CCNG1 CCNA2 CCNA2 SOWAHB SOWAHB CCNG2 CCNG2 CDKN2D CDKN2D CDKN1A CDKN1A CCNE2 CCNE2 HEXIM2 HEXIM2 CCNJL CCNJL CCNY CCNY CKS1B CKS1B CDKN2C CDKN2C CASP3 CASP3 CCNC CCNC ENSFCAP00000037196 ENSFCAP00000037196 CCNB1 CCNB1 CCND3 CCND3 ENSFCAP00000041398 ENSFCAP00000041398 CCNK CCNK CCND2 CCND2 CDK5R2 CDK5R2 CDKN1C CDKN1C CDKN1B CDKN1B GPRC5C GPRC5C CCNT1 CCNT1 ENSFCAP00000048496 ENSFCAP00000048496 MNAT1 MNAT1 CCND1 CCND1 INCA1 INCA1 CCNL2 CCNL2 CCNI CCNI CCNL1 CCNL1 CCNT2 CCNT2 CCNH CCNH ENSFCAP00000061217 ENSFCAP00000061217
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNOCyclin O; Belongs to the cyclin family. (351 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (410 aa)
CCNFCyclin F; Belongs to the cyclin family. (848 aa)
CCNQCyclin Q; Belongs to the cyclin family. (376 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (421 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (397 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (192 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (363 aa)
CCNJCyclin J; Belongs to the cyclin family. (383 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
SOWAHBSosondowah ankyrin repeat domain family member B. (782 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (343 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
CDKN1ACyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (406 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (292 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (388 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
ENSFCAP00000037196Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (56 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (600 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
ENSFCAP00000041398CYCLIN domain-containing protein; Belongs to the cyclin family. (263 aa)
CCNKCyclin K; Belongs to the cyclin family. (582 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (370 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (264 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa)
GPRC5CG protein-coupled receptor class C group 5 member C. (486 aa)
CCNT1CYCLIN domain-containing protein; Belongs to the cyclin family. (184 aa)
ENSFCAP00000048496Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (62 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (312 aa)
INCA1Inhibitor of CDK, cyclin A1 interacting protein 1. (256 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (565 aa)
CCNICyclin I; Belongs to the cyclin family. (380 aa)
CCNL1Cyclin L1; Belongs to the cyclin family. (557 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (742 aa)
CCNHCyclin H; Belongs to the cyclin family. (326 aa)
ENSFCAP00000061217Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (247 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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