(44 nodes) Intramolecular oxidoreductase activity network (Felis catus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	QSOX2	Sulfhydryl oxidase. (701 aa)
	MRI1	Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (343 aa)
	DDT	D-dopachrome tautomerase like. (118 aa)
	PDIA6	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (440 aa)
	PDIA4	Protein disulfide-isomerase A4. (645 aa)
	RPIA	Ribose 5-phosphate isomerase A. (311 aa)
	ECI1	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (302 aa)
	PDIA3	Protein disulfide-isomerase. (505 aa)
	PTGES3	Prostaglandin E synthase 3. (164 aa)
	IDI1	Isopentenyl-diphosphate delta isomerase 1. (281 aa)
	PDIA5	Protein disulfide isomerase family A member 5. (521 aa)
	PTGDS	Prostaglandin-H2 D-isomerase; Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possib [...] (364 aa)
	PTGES2	Prostaglandin E synthase 2. (373 aa)
	QSOX1	Sulfhydryl oxidase. (858 aa)
	GNPDA1	Glucosamine-6-phosphate isomerase. (304 aa)
	TBXAS1	Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (558 aa)
	CRELD2	Cysteine rich with EGF like domains 2. (365 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (523 aa)
	ERP27	Endoplasmic reticulum protein 27. (276 aa)
	MIF	Macrophage migration inhibitory factor. (190 aa)
	ECH1	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (380 aa)
	LOC101095082	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (347 aa)
	HYI	Putative hydroxypyruvate isomerase; Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the hyi family. (305 aa)
	MPI	Mannose-6-phosphate isomerase. (421 aa)
	HPGDS	Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
	ENOPH1	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (659 aa)
	TXNDC5	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (436 aa)
	PTGES	Prostaglandin E synthase. (153 aa)
	PTGIS	Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (415 aa)
	DCT	Dopachrome tautomerase. (664 aa)
	EBPL	EBP like. (206 aa)
	TMX3	Thioredoxin related transmembrane protein 3. (521 aa)
	HSD3B2	3 beta-hydroxysteroid dehydrogenase; Belongs to the 3-beta-HSD family. (373 aa)
	P4HB	Protein disulfide-isomerase. (510 aa)
	TPI1	Triosephosphate isomerase. (286 aa)
	GNPDA2	Glucosamine-6-phosphate isomerase. (276 aa)
	EBP	EXPERA domain-containing protein. (230 aa)
	TXNDC16	Thioredoxin domain containing 16. (821 aa)
	PDILT	Protein disulfide isomerase like, testis expressed. (580 aa)
	ERP44	Endoplasmic reticulum protein 44. (485 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (324 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRELD2	EBPL	ENSFCAP00000057915	ENSFCAP00000029213	Cysteine rich with EGF like domains 2.	EBP like.	0.591
CRELD2	PDIA3	ENSFCAP00000057915	ENSFCAP00000006138	Cysteine rich with EGF like domains 2.	Protein disulfide-isomerase.	0.517
CRELD2	PDIA4	ENSFCAP00000057915	ENSFCAP00000007991	Cysteine rich with EGF like domains 2.	Protein disulfide-isomerase A4.	0.850
CRELD2	PDIA5	ENSFCAP00000057915	ENSFCAP00000000872	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 5.	0.551
CRELD2	PDIA6	ENSFCAP00000057915	ENSFCAP00000008583	Cysteine rich with EGF like domains 2.	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.	0.732
CRELD2	TMX3	ENSFCAP00000057915	ENSFCAP00000028360	Cysteine rich with EGF like domains 2.	Thioredoxin related transmembrane protein 3.	0.400
EBP	IDI1	ENSFCAP00000020468	ENSFCAP00000002496	EXPERA domain-containing protein.	Isopentenyl-diphosphate delta isomerase 1.	0.624
EBPL	CRELD2	ENSFCAP00000029213	ENSFCAP00000057915	EBP like.	Cysteine rich with EGF like domains 2.	0.591
ECH1	ECHS1	ENSFCAP00000053473	ENSFCAP00000014105	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.568
ECH1	ECI1	ENSFCAP00000053473	ENSFCAP00000007117	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.761
ECH1	ECI2	ENSFCAP00000053473	ENSFCAP00000031941	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 2.	0.797
ECHS1	ECH1	ENSFCAP00000014105	ENSFCAP00000053473	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.568
ECHS1	ECI1	ENSFCAP00000014105	ENSFCAP00000007117	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.750
ECHS1	ECI2	ENSFCAP00000014105	ENSFCAP00000031941	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 2.	0.486
ECI1	ECH1	ENSFCAP00000007117	ENSFCAP00000053473	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.761
ECI1	ECHS1	ENSFCAP00000007117	ENSFCAP00000014105	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.750
ECI1	ECI2	ENSFCAP00000007117	ENSFCAP00000031941	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Enoyl-CoA delta isomerase 2.	0.873
ECI2	ECH1	ENSFCAP00000031941	ENSFCAP00000053473	Enoyl-CoA delta isomerase 2.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.797
ECI2	ECHS1	ENSFCAP00000031941	ENSFCAP00000014105	Enoyl-CoA delta isomerase 2.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.486
ECI2	ECI1	ENSFCAP00000031941	ENSFCAP00000007117	Enoyl-CoA delta isomerase 2.	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.873