STRINGSTRING
HIF1A HIF1A PRAME PRAME MED25 MED25 WIPI1 WIPI1 SMARCE1-2 SMARCE1-2 ARID5A ARID5A NRBF2 NRBF2 PPARGC1B PPARGC1B PPARGC1A PPARGC1A TACC2 TACC2 ENSFCAP00000053614 ENSFCAP00000053614 NKX3-1 NKX3-1 DCAF13 DCAF13 TRIP4 TRIP4 NR1H3 NR1H3 CTBP2 CTBP2 RARG RARG SMARCD3 SMARCD3 DAXX-2 DAXX-2 BCAS3 BCAS3 HMGA1 HMGA1 LOC101093046 LOC101093046 STRN STRN TCF7L2 TCF7L2 RXRA RXRA LEF1 LEF1 NR4A3 NR4A3 YWHAH YWHAH NCOA6 NCOA6 ARID1A ARID1A SRARP SRARP MED1 MED1 FOXP1 FOXP1 NCOA1 NCOA1 MED17 MED17 MED12 MED12 CRX CRX ZBTB7A ZBTB7A TAF7 TAF7 PRPF6 PRPF6 RNF14 RNF14 NCOA7 NCOA7 SMAD3 SMAD3 NCOR1 NCOR1 MED24 MED24 THRAP3 THRAP3 GRIP1 GRIP1 PKN1 PKN1 SIRT1 SIRT1 LOC101092829 LOC101092829 ACTN4 ACTN4 DCAF1 DCAF1 LRIF1 LRIF1 C1D C1D CRY1 CRY1 DNAAF4 DNAAF4 BUD31 BUD31 LATS1 LATS1 BRD8 BRD8 TCF21 TCF21 VDR VDR TMF1 TMF1 CNOT1 CNOT1 PPID PPID MED30 MED30 ESR1 ESR1 FOXH1 FOXH1 PARK7 PARK7 NCOA2 NCOA2 PAGR1 PAGR1 TAF7L TAF7L SLC30A9 SLC30A9 PROX1 PROX1 NR0B1 NR0B1 TACC1 TACC1 DDX54 DDX54 TAF10 TAF10 MED4 MED4 TRIM68 TRIM68 NCOA3 NCOA3 MED13 MED13 PRMT2 PRMT2 TADA3 TADA3 KDM1A KDM1A MMS19 MMS19 NR4A2 NR4A2 RNF6 RNF6 PRKCB PRKCB KDM3A KDM3A PADI2 PADI2 SMARCE1 SMARCE1 NR1H2 NR1H2 TGFB1I1 TGFB1I1 NRIP1 NRIP1 MED16 MED16 GTF2H1 GTF2H1 NR1H4 NR1H4 CCDC62 CCDC62 NR1I2 NR1I2 GTF2B GTF2B ZNF366 ZNF366 EP300 EP300 MYOD1 MYOD1 TRIM24 TRIM24 DAXX DAXX TOB2 TOB2 DDX5 DDX5 CRY2 CRY2 STAT5B STAT5B ASXL1 ASXL1 SNW1 SNW1 NSD1 NSD1 NR4A1 NR4A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
PRAMEPreferentially expressed antigen in melanoma. (512 aa)
MED25Mediator complex subunit 25. (795 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (470 aa)
SMARCE1-2HMG box domain-containing protein. (139 aa)
ARID5AAT-rich interaction domain 5A. (608 aa)
NRBF2Nuclear receptor binding factor 2. (288 aa)
PPARGC1BPPARG coactivator 1 beta. (1006 aa)
PPARGC1APPARG coactivator 1 alpha. (803 aa)
TACC2Transforming acidic coiled-coil containing protein 2. (2952 aa)
ENSFCAP00000053614Uncharacterized protein. (81 aa)
NKX3-1NK3 homeobox 1. (231 aa)
DCAF13DDB1 and CUL4 associated factor 13. (450 aa)
TRIP4Thyroid hormone receptor interactor 4. (605 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (498 aa)
CTBP2C-terminal binding protein 2. (977 aa)
RARGRetinoic acid receptor gamma. (459 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa)
DAXX-2Daxx domain-containing protein. (769 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (959 aa)
HMGA1High mobility group AT-hook 1. (107 aa)
LOC101093046Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (208 aa)
STRNStriatin. (780 aa)
TCF7L2Transcription factor 7 like 2. (673 aa)
RXRARetinoid X receptor alpha. (654 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (651 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta. (69 aa)
NCOA6Nuclear receptor coactivator 6. (2080 aa)
ARID1AAT-rich interaction domain 1A. (2284 aa)
SRARPSteroid receptor associated and regulated protein. (169 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
FOXP1Forkhead box P1. (693 aa)
NCOA1Nuclear receptor coactivator. (1492 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (692 aa)
MED12Mediator complex subunit 12. (2278 aa)
CRXCone-rod homeobox protein. (299 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
TAF7TATA-box binding protein associated factor 7. (349 aa)
PRPF6Pre-mRNA processing factor 6. (955 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
NCOA7Nuclear receptor coactivator 7. (942 aa)
SMAD3Mothers against decapentaplegic homolog. (457 aa)
NCOR1Nuclear receptor corepressor 1. (2515 aa)
MED24Mediator complex subunit 24. (1023 aa)
THRAP3Thyroid hormone receptor associated protein 3. (958 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
PKN1Protein kinase N1. (1064 aa)
SIRT1Sirtuin 1. (745 aa)
LOC101092829Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (165 aa)
ACTN4Actinin alpha 4. (933 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1507 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (762 aa)
C1DC1D nuclear receptor corepressor. (178 aa)
CRY1Cryptochrome circadian regulator 1. (587 aa)
DNAAF4Dynein axonemal assembly factor 4. (475 aa)
BUD31BUD31 homolog. (144 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
BRD8Bromodomain containing 8. (1236 aa)
TCF21Transcription factor 21. (179 aa)
VDRVitamin D receptor. (441 aa)
TMF1TATA element modulatory factor 1. (1093 aa)
CNOT1CCR4-NOT transcription complex subunit 1. (2383 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
MED30Mediator complex subunit 30. (178 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
FOXH1Forkhead box H1. (361 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
NCOA2Nuclear receptor coactivator. (1470 aa)
PAGR1PAXIP1 associated glutamate rich protein 1. (254 aa)
TAF7LTATA-box binding protein associated factor 7 like. (489 aa)
SLC30A9Solute carrier family 30 member 9. (571 aa)
PROX1Prospero homeobox 1. (737 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (471 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (801 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (877 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
TRIM68Tripartite motif containing 68. (485 aa)
NCOA3Nuclear receptor coactivator. (1412 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
PRMT2Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (434 aa)
TADA3Transcriptional adaptor 3. (432 aa)
KDM1ALysine demethylase 1A. (944 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
RNF6Ring finger protein 6. (683 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
KDM3ALysine demethylase 3A. (1324 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (376 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (457 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (464 aa)
NRIP1Nuclear receptor interacting protein 1. (1155 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (828 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
CCDC62Coiled-coil domain containing 62. (687 aa)
NR1I2Nuclear receptor subfamily 1 group I member 2. (434 aa)
GTF2BGeneral transcription factor IIB. (285 aa)
ZNF366Zinc finger protein 366. (845 aa)
EP300E1A binding protein p300. (2425 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
TRIM24Tripartite motif containing 24. (1268 aa)
DAXXDeath domain associated protein. (748 aa)
TOB2Transducer of ERBB2, 2. (335 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
CRY2Cryptochrome circadian regulator 2. (594 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
ASXL1ASXL transcriptional regulator 1. (1545 aa)
SNW1SNW domain containing 1. (570 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2701 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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