STRINGSTRING
AURKC AURKC MAPK13 MAPK13 CHUK CHUK ENSFCAP00000060774 ENSFCAP00000060774 LATS2 LATS2 AKT2 AKT2 BAK1 BAK1 ENSFCAP00000058884 ENSFCAP00000058884 PKD1 PKD1 CSNK1G1 CSNK1G1 ENSFCAP00000057420 ENSFCAP00000057420 VRK3 VRK3 STK38 STK38 VRK2 VRK2 PRKCZ PRKCZ RPS6KB2 RPS6KB2 SGK1 SGK1 MARK3 MARK3 TBK1 TBK1 HIPK3 HIPK3 UHMK1 UHMK1 AURKB AURKB MAP3K13 MAP3K13 TTBK1 TTBK1 MKNK1 MKNK1 CLK1 CLK1 RICTOR RICTOR TGFBR1 TGFBR1 MAPK9 MAPK9 CHEK2 CHEK2 CSNK2A1 CSNK2A1 NEK6 NEK6 GALK1 GALK1 MAP4K1 MAP4K1 CAMK1D CAMK1D SBK1 SBK1 IKBKB IKBKB CSNK1D CSNK1D GSK3B GSK3B RPS6KA2 RPS6KA2 ENSFCAP00000043165 ENSFCAP00000043165 DYRK1A DYRK1A SMG1 SMG1 PRKCQ PRKCQ NEK7 NEK7 CSNK1A1 CSNK1A1 DYRK4 DYRK4 DCLK1 DCLK1 VRK1 VRK1 HIPK1 HIPK1 ROCK1 ROCK1 LOC101101321 LOC101101321 CAMK1G CAMK1G PRKDC PRKDC CEP170 CEP170 PRKCE PRKCE MAPKAPK5 MAPKAPK5 MAST1 MAST1 RPS6KA1 RPS6KA1 PRKAA2 PRKAA2 STK32B STK32B CDK2 CDK2 MAPK12 MAPK12 DYRK1B DYRK1B PKN1 PKN1 RPS6KA3 RPS6KA3 TNKS TNKS STK32C STK32C CLSPN CLSPN PRKD1 PRKD1 MTOR MTOR PCK1 PCK1 RPS6KA4 RPS6KA4 PINK1 PINK1 HIPK4 HIPK4 CAMK4 CAMK4 PRKCG PRKCG RPS6KA5 RPS6KA5 LRRK2 LRRK2 SGK2 SGK2 PDPK1 PDPK1 MYO3A MYO3A MORC3 MORC3 GRK2 GRK2 ERN1 ERN1 TTBK2 TTBK2 AKT3 AKT3 TLK1 TLK1 ULK3 ULK3 PRKCD PRKCD PNCK PNCK AKT1 AKT1 TSSK4 TSSK4 PKN3 PKN3 EPO EPO GAS6 GAS6 MAPKAPK3 MAPKAPK3 NLK NLK MAST3 MAST3 STK32A STK32A MAPK7 MAPK7 NTRK2 NTRK2 RPS6KA6 RPS6KA6 PRKD2 PRKD2 CAMKV CAMKV ULK1 ULK1 TLK2 TLK2 DYRK2 DYRK2 PRKCB PRKCB STK39 STK39 PRKCA PRKCA MYO3B MYO3B MKNK2 MKNK2 MAP3K10 MAP3K10 DGKQ DGKQ MAP3K12 MAP3K12 PRKCH PRKCH PLK1 PLK1 MAPKAPK2 MAPKAPK2 IKBKE IKBKE CAMK1 CAMK1 SYK SYK MAST2 MAST2 TSSK6 TSSK6 PBK PBK RIPK1 RIPK1 CDK1 CDK1 ILK ILK PDGFB PDGFB SBK2 SBK2 ATR ATR PRKX PRKX PAK2 PAK2 STK38L STK38L AURKA AURKA SGK3 SGK3 TSSK1B TSSK1B SMTNL1 SMTNL1 STK4 STK4 TTK TTK CSNK2A2 CSNK2A2 MAST4 MAST4 DCLK3 DCLK3 PKN2 PKN2 H3F3A H3F3A PRPF4B PRPF4B CDK5 CDK5 RPS6KB1 RPS6KB1 LATS1 LATS1 GSK3A GSK3A CDC7 CDC7 PRKAA1 PRKAA1 PRKCI PRKCI DYRK3 DYRK3 CAB39 CAB39 MAPK1 MAPK1 ATM ATM HIPK2 HIPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (278 aa)
MAPK13Mitogen-activated protein kinase. (402 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (774 aa)
ENSFCAP00000060774Protein kinase domain-containing protein. (78 aa)
LATS2Non-specific serine/threonine protein kinase. (1095 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
ENSFCAP00000058884Protein kinase domain-containing protein. (375 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4299 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (483 aa)
ENSFCAP00000057420Uncharacterized protein. (443 aa)
VRK3VRK serine/threonine kinase 3. (453 aa)
STK38Serine/threonine kinase 38; Belongs to the protein kinase superfamily. (449 aa)
VRK2VRK serine/threonine kinase 2. (495 aa)
PRKCZProtein kinase C zeta. (649 aa)
RPS6KB2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
SGK1Non-specific serine/threonine protein kinase. (584 aa)
MARK3Non-specific serine/threonine protein kinase. (822 aa)
TBK1TANK binding kinase 1. (729 aa)
HIPK3Homeodomain interacting protein kinase 3. (1221 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (408 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1021 aa)
TTBK1Tau tubulin kinase 1. (1314 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (419 aa)
CLK1CDC like kinase 1; Belongs to the protein kinase superfamily. (484 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CHEK2Checkpoint kinase 2. (569 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
NEK6NIMA related kinase 6. (534 aa)
GALK1Galactokinase 1. (619 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID. (392 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (420 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (760 aa)
CSNK1DCasein kinase 1 delta. (488 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
RPS6KA2Ribosomal protein S6 kinase. (741 aa)
ENSFCAP00000043165Uncharacterized protein. (62 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3659 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (715 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (314 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (380 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (637 aa)
DCLK1Doublecortin like kinase 1. (741 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (418 aa)
HIPK1Homeodomain interacting protein kinase 1. (1289 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
LOC101101321Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (457 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (494 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4108 aa)
CEP170Centrosomal protein 170. (1588 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1571 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
STK32BSerine/threonine kinase 32B; Belongs to the protein kinase superfamily. (414 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (789 aa)
PKN1Protein kinase N1. (1064 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
STK32CSerine/threonine kinase 32C; Belongs to the protein kinase superfamily. (485 aa)
CLSPNClaspin. (1327 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (930 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
RPS6KA4Ribosomal protein S6 kinase. (771 aa)
PINK1PTEN induced kinase 1. (581 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (638 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
RPS6KA5Ribosomal protein S6 kinase. (798 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1618 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (972 aa)
TTBK2Tau tubulin kinase 2. (1252 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TLK1Tousled like kinase 1. (766 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase; Belongs to the protein kinase superfamily. (343 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
PKN3Protein kinase N3. (887 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (192 aa)
GAS6Growth arrest specific 6. (674 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1302 aa)
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (396 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (804 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (885 aa)
CAMKVCaM kinase like vesicle associated. (499 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1113 aa)
TLK2Tousled like kinase 2. (799 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
STK39Serine/threonine kinase 39. (543 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1367 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (610 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (937 aa)
DGKQDiacylglycerol kinase. (942 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
MAPKAPK2MAPK activated protein kinase 2. (409 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1799 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (376 aa)
PBKPDZ binding kinase. (337 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa)
ILKIntegrin linked kinase. (451 aa)
PDGFBPlatelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa)
SBK2SH3 domain binding kinase family member 2; Belongs to the protein kinase superfamily. (349 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2643 aa)
PRKXUncharacterized protein. (416 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (463 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (404 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
TSSK1BTestis specific serine kinase 1B; Belongs to the protein kinase superfamily. (369 aa)
SMTNL1Smoothelin like 1. (478 aa)
STK4Serine/threonine kinase 4. (487 aa)
TTKTTK protein kinase. (856 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
MAST4Uncharacterized protein. (1369 aa)
DCLK3Doublecortin like kinase 3. (798 aa)
PKN2Protein kinase N2. (983 aa)
H3F3AHistone H3; Belongs to the histone H3 family. (136 aa)
PRPF4BPre-mRNA processing factor 4B. (1041 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
CDC7Cell division cycle 7. (574 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (587 aa)
CAB39Calcium binding protein 39. (373 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
HIPK2Homeodomain interacting protein kinase 2. (1222 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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