STRINGSTRING
KDM2B KDM2B DRAXIN DRAXIN PEX5 PEX5 LRRK2 LRRK2 KAT2A KAT2A NR2E1 NR2E1 IGF2BP1 IGF2BP1 NRGN NRGN SLIT1 SLIT1 MAS1 MAS1 RYK RYK HIF1A HIF1A CSF1R CSF1R SLC7A11 SLC7A11 CHD7 CHD7 NF2 NF2 CB4H12orf57 CB4H12orf57 NUMBL NUMBL LAMB1 LAMB1 DCX DCX LHX5 LHX5 XRCC1 XRCC1 SUN1 SUN1 CRKL CRKL BCAN BCAN CNTN2 CNTN2 MDGA1 MDGA1 LHX2 LHX2 PAX6 PAX6 ATAT1 ATAT1 SEMA7A SEMA7A MKKS MKKS CDK5R1 CDK5R1 BBS2 BBS2 NKX2-2 NKX2-2 EPHB3 EPHB3 NTRK2 NTRK2 RARB RARB TRA2B TRA2B ALDH1A3 ALDH1A3 FECH FECH TTC8 TTC8 MPP5 MPP5 TCTN1 TCTN1 EFHC1 EFHC1 ZMIZ1 ZMIZ1 POU3F4 POU3F4 GLI3 GLI3 FEZF2 FEZF2 NDE1 NDE1 ZDHHC16 ZDHHC16 FEZF1 FEZF1 WDR62 WDR62 TNR TNR COL3A1 COL3A1 MBOAT7 MBOAT7 AKIRIN2 AKIRIN2 UCHL5 UCHL5 ZSWIM6 ZSWIM6 PTEN PTEN TRAPPC9 TRAPPC9 SUN2 SUN2 TACC1 TACC1 SALL1 SALL1 PROX1 PROX1 PEX13 PEX13 CCDC141 CCDC141 SRF SRF UQCRQ UQCRQ KIF14 KIF14 TMEM108 TMEM108 CDK5 CDK5 GSX2 GSX2 ASPM ASPM RTN4 RTN4 FOXB1 FOXB1 SEMA3A SEMA3A HSD3B2 HSD3B2 ARL13B ARL13B NIN NIN DLX2 DLX2 PAFAH1B1 PAFAH1B1 RTN4RL1 RTN4RL1 RTN4R RTN4R DAB2IP DAB2IP AQP1 AQP1 SLITRK5 SLITRK5 FBXO45 FBXO45 FAT4 FAT4 BMP2 BMP2 ENSFCAP00000031105 ENSFCAP00000031105 MFSD2A MFSD2A CDON CDON BBS4 BBS4 NKX2-1 NKX2-1 NRG3 NRG3 CELF1 CELF1 DPCD DPCD LHX1 LHX1 ATOH1 ATOH1 BTG2 BTG2 SLIT2 SLIT2 BCL11B BCL11B BTBD3 BTBD3 RFX4 RFX4 LRP8 LRP8 FUT1 FUT1 HES5 HES5 ARX ARX ZSWIM5 ZSWIM5 ERBB4 ERBB4 TSC1 TSC1 DLX5 DLX5 TSKU TSKU CDK5R2 CDK5R2 GSK3B GSK3B DMRTA2 DMRTA2 ALK ALK EXT1 EXT1 PTPRS PTPRS CRK CRK INHBA INHBA AGTPBP1 AGTPBP1 SZT2 SZT2 TBR1 TBR1 KIRREL3 KIRREL3 EMX2 EMX2 BAD BAD ATF5 ATF5 ENSFCAP00000048141 ENSFCAP00000048141 LEF1 LEF1 OGDH OGDH EMX1 EMX1 MGARP MGARP CCDC85C CCDC85C FOXG1 FOXG1 POU3F3 POU3F3 SCT SCT NUMB NUMB DLX1 DLX1 FAM205A FAM205A SYNE2 SYNE2 BMP4 BMP4 HES1 HES1 DIXDC1 DIXDC1 ZIC3 ZIC3 SLC1A2 SLC1A2 SECISBP2 SECISBP2 BMERB1 BMERB1 ADGRG1 ADGRG1 ZSWIM4 ZSWIM4 TACC2 TACC2 NDEL1 NDEL1 NFIB NFIB NF1 NF1 ENSFCAP00000055751 ENSFCAP00000055751 RPGRIP1L RPGRIP1L ASCL1 ASCL1 ENSFCAP00000057441 ENSFCAP00000057441 RELN RELN CEP120 CEP120 NEUROD6 NEUROD6 ATP1B2 ATP1B2 MCPH1 MCPH1 JAKMIP3 JAKMIP3 PHACTR1 PHACTR1 POU3F2 POU3F2 SMO SMO BBS1 BBS1 UBA6 UBA6 NPY NPY PLXNA3 PLXNA3 JAKMIP2 JAKMIP2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KDM2BLysine demethylase 2B. (1264 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (377 aa)
PEX5Peroxisomal biogenesis factor 5. (640 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (836 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
NRGNNeurogranin. (78 aa)
SLIT1Slit guidance ligand 1. (1518 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
RYKReceptor like tyrosine kinase. (609 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...] (1213 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
NF2Neurofibromin 2. (596 aa)
CB4H12orf57Chromosome B4 C12orf57 homolog. (126 aa)
NUMBLNUMB like endocytic adaptor protein. (678 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
DCXDoublecortin. (365 aa)
LHX5LIM homeobox 5. (402 aa)
XRCC1X-ray repair cross complementing 1. (631 aa)
SUN1Sad1 and UNC84 domain containing 1. (940 aa)
CRKLCRK like proto-oncogene, adaptor protein. (342 aa)
BCANBrevican core protein; May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans; Belongs to the aggrecan/versican proteoglycan family. (908 aa)
CNTN2Contactin 2. (1103 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (955 aa)
LHX2LIM homeobox 2. (406 aa)
PAX6Paired box 6. (437 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (421 aa)
SEMA7ASemaphorin 7A; Belongs to the semaphorin family. (769 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (720 aa)
NKX2-2NK2 homeobox 2. (273 aa)
EPHB3EPH receptor B3. (1000 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
RARBRetinoic acid receptor beta. (448 aa)
TRA2BTransformer 2 beta homolog. (288 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
FECHAsparaginyl-tRNA synthetase. (613 aa)
TTC8Tetratricopeptide repeat domain 8. (515 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
TCTN1Tectonic family member 1. (589 aa)
EFHC1EF-hand domain containing 1. (643 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1066 aa)
POU3F4POU domain protein. (361 aa)
GLI3GLI family zinc finger 3. (1578 aa)
FEZF2FEZ family zinc finger 2. (464 aa)
NDE1NudE neurodevelopment protein 1. (393 aa)
ZDHHC16Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (377 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
WDR62WD repeat domain 62. (1534 aa)
TNRTenascin R. (1358 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
AKIRIN2Akirin 2. (203 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (341 aa)
ZSWIM6Zinc finger SWIM-type containing 6. (1244 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TRAPPC9Trafficking protein particle complex 9. (1147 aa)
SUN2Sad1 and UNC84 domain containing 2. (749 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (801 aa)
SALL1Spalt like transcription factor 1. (1238 aa)
PROX1Prospero homeobox 1. (737 aa)
PEX13SH3 domain-containing protein. (403 aa)
CCDC141Coiled-coil domain containing 141. (1531 aa)
SRFSerum response factor. (512 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1575 aa)
TMEM108Transmembrane protein 108. (581 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
GSX2GS homeobox 2. (305 aa)
ASPMAbnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3478 aa)
RTN4Reticulon. (1190 aa)
FOXB1Forkhead box B1. (325 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (773 aa)
HSD3B23 beta-hydroxysteroid dehydrogenase; Belongs to the 3-beta-HSD family. (373 aa)
ARL13BADP ribosylation factor like GTPase 13B. (427 aa)
NINNinein. (2128 aa)
DLX2Distal-less homeobox 2. (331 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
RTN4RL1Reticulon 4 receptor like 1. (445 aa)
RTN4RReticulon 4 receptor. (474 aa)
DAB2IPDAB2 interacting protein. (1166 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
SLITRK5SLIT and NTRK like family member 5. (958 aa)
FBXO45F-box protein 45. (285 aa)
FAT4FAT atypical cadherin 4. (4982 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
ENSFCAP00000031105SH3 domain-containing protein. (373 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (529 aa)
CDONCell adhesion associated, oncogene regulated. (1283 aa)
BBS4Bardet-Biedl syndrome 4. (525 aa)
NKX2-1NK2 homeobox 1. (399 aa)
NRG3Neuregulin 3. (720 aa)
CELF1CUGBP Elav-like family member 1. (514 aa)
DPCDDeleted in primary ciliary dyskinesia homolog (mouse). (246 aa)
LHX1LIM homeobox 1. (406 aa)
ATOH1Atonal bHLH transcription factor 1. (356 aa)
BTG2BTG anti-proliferation factor 2. (162 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
BCL11BUncharacterized protein. (895 aa)
BTBD3BTB domain containing 3. (594 aa)
RFX4Regulatory factor X4. (744 aa)
LRP8LDL receptor related protein 8. (1015 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (491 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
ARXAristaless related homeobox. (562 aa)
ZSWIM5Zinc finger SWIM-type containing 5. (1185 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
TSC1TSC complex subunit 1. (1110 aa)
DLX5Homeobox domain-containing protein. (289 aa)
TSKUTsukushi, small leucine rich proteoglycan. (390 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (370 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
DMRTA2DMRT like family A2. (535 aa)
ALKTyrosine-protein kinase receptor. (1279 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1947 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
INHBAInhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins (By similarity). (424 aa)
AGTPBP1ATP/GTP binding protein 1. (1227 aa)
SZT2SZT2 subunit of KICSTOR complex. (3430 aa)
TBR1T-box brain transcription factor 1. (682 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (778 aa)
EMX2Empty spiracles homeobox 2. (253 aa)
BADBCL2 associated agonist of cell death. (273 aa)
ATF5Activating transcription factor 5. (280 aa)
ENSFCAP00000048141Uncharacterized protein. (413 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
EMX1Empty spiracles homeobox 1. (296 aa)
MGARPMitochondria localized glutamic acid rich protein. (241 aa)
CCDC85CUncharacterized protein. (64 aa)
FOXG1Forkhead box G1. (483 aa)
POU3F3POU class 3 homeobox 3. (528 aa)
SCTSecretin. (126 aa)
NUMBNUMB endocytic adaptor protein. (653 aa)
DLX1Distal-less homeobox 1. (255 aa)
FAM205AUncharacterized protein. (1294 aa)
SYNE2KASH domain-containing protein. (3641 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
DIXDC1DIX domain containing 1. (690 aa)
ZIC3Zic family member 3. (553 aa)
SLC1A2Amino acid transporter. (579 aa)
SECISBP2SECIS binding protein 2. (866 aa)
BMERB1BMERB domain containing 1. (204 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (689 aa)
ZSWIM4Zinc finger SWIM-type containing 4. (1117 aa)
TACC2Transforming acidic coiled-coil containing protein 2. (2952 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (480 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
NF1Neurofibromin 1. (2856 aa)
ENSFCAP00000055751Uncharacterized protein. (272 aa)
RPGRIP1LRPGRIP1 like. (1392 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (246 aa)
ENSFCAP00000057441Uncharacterized protein. (138 aa)
RELNReelin. (3460 aa)
CEP120Centrosomal protein 120. (987 aa)
NEUROD6Neurogenic differentiation factor. (303 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (306 aa)
MCPH1Uncharacterized protein. (852 aa)
JAKMIP3Janus kinase and microtubule interacting protein 3. (980 aa)
PHACTR1Phosphatase and actin regulator. (801 aa)
POU3F2POU domain protein. (343 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa)
BBS1BBS1 domain-containing protein. (602 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1111 aa)
NPYNeuropeptide Y; Belongs to the NPY family. (249 aa)
PLXNA3Plexin A3. (1872 aa)
JAKMIP2Janus kinase and microtubule interacting protein 2. (822 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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