STRINGSTRING
KIT KIT ARHGEF6 ARHGEF6 SPEF1 SPEF1 ABLIM1 ABLIM1 PARVB PARVB CARMIL1 CARMIL1 SPATA13 SPATA13 ABLIM2 ABLIM2 CCDC88A CCDC88A DMTN DMTN VAV3 VAV3 ENSFCAP00000045292 ENSFCAP00000045292 RHOD RHOD PTPRO PTPRO SH2B1 SH2B1 ABLIM3 ABLIM3 NCK1 NCK1 ENSFCAP00000038864 ENSFCAP00000038864 ARHGEF7 ARHGEF7 VCL VCL NUP85 NUP85 CYFIP1 CYFIP1 VAV2 VAV2 WASF3 WASF3 WASF2 WASF2 AJUBA AJUBA CDH13 CDH13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (979 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (775 aa)
SPEF1Sperm flagellar 1. (343 aa)
ABLIM1Actin binding LIM protein 1. (830 aa)
PARVBParvin beta. (413 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1420 aa)
SPATA13Uncharacterized protein. (1320 aa)
ABLIM2Actin binding LIM protein family member 2. (716 aa)
CCDC88ACoiled-coil domain containing 88A. (1874 aa)
DMTNDematin actin binding protein. (405 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
ENSFCAP00000045292CH_2 domain-containing protein. (564 aa)
RHODRas homolog family member D. (210 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
SH2B1SH2B adaptor protein 1. (757 aa)
ABLIM3Actin binding LIM protein family member 3. (683 aa)
NCK1Cytoplasmic protein. (455 aa)
ENSFCAP00000038864Uncharacterized protein. (100 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (921 aa)
VCLVinculin. (1066 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (655 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
WASF3WASP family member 3. (502 aa)
WASF2WASP family member 2. (498 aa)
AJUBAAjuba LIM protein. (548 aa)
CDH13Cadherin 13. (713 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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