STRINGSTRING
POMGNT1 POMGNT1 DCP2 DCP2 XPNPEP1 XPNPEP1 ADPRM ADPRM MGAT5B MGAT5B ABL1 ABL1 ABL2 ABL2 PPEF2 PPEF2 PEPD PEPD DYRK2 DYRK2 ME3 ME3 FEN1 FEN1 ARG2 ARG2 FASTKD3 FASTKD3 PPM1M PPM1M MGAT5 MGAT5 LARGE1 LARGE1 MTPAP MTPAP TDP2 TDP2 NPEPL1 NPEPL1 B4GALT7 B4GALT7 B4GALT1 B4GALT1 NUDT7 NUDT7 WRN WRN PPM1B PPM1B GALNT1 GALNT1 PIM1 PIM1 PRIMPOL PRIMPOL MRE11 MRE11 PPM1N PPM1N FAM20C FAM20C SOD2 SOD2 PPEF1 PPEF1 ME1 ME1 EXTL2 EXTL2 PCK2 PCK2 MGAT2 MGAT2 MGAT1 MGAT1 GYG1 GYG1 PCK1 PCK1 GALNT3 GALNT3 PPM1A PPM1A ATP2C1 ATP2C1 MPPE1 MPPE1 CCP110 CCP110 XXYLT1 XXYLT1 IMPA1 IMPA1 XPNPEP3 XPNPEP3 GALNT2 GALNT2 ARG1 ARG1 LAP3 LAP3 NUDT16 NUDT16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POMGNT1Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-). (660 aa)
DCP2Decapping mRNA 2. (422 aa)
XPNPEP1X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family. (666 aa)
ADPRMADP-ribose/CDP-alcohol diphosphatase, manganese dependent. (377 aa)
MGAT5BAlpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B. (792 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
ABL2Tyrosine-protein kinase. (1160 aa)
PPEF2Serine/threonine-protein phosphatase with EF-hands. (752 aa)
PEPDPeptidase D. (493 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
ME3Malic enzyme. (604 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
ARG2Arginase. (354 aa)
FASTKD3FAST kinase domains 3. (627 aa)
PPM1MProtein phosphatase, Mg2+/Mn2+ dependent 1M. (461 aa)
MGAT5Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (780 aa)
LARGE1LARGE xylosyl- and glucuronyltransferase 1. (756 aa)
MTPAPMitochondrial poly(A) polymerase. (584 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (362 aa)
NPEPL1Aminopeptidase like 1. (523 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (381 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (400 aa)
NUDT7Nudix hydrolase 7. (238 aa)
WRNWRN RecQ like helicase. (1406 aa)
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
GALNT1Polypeptide N-acetylgalactosaminyltransferase. (559 aa)
PIM1Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] (313 aa)
PRIMPOLPrimase and DNA directed polymerase. (556 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (738 aa)
PPM1NProtein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (423 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (615 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
PPEF1Serine/threonine-protein phosphatase with EF-hands. (660 aa)
ME1Malic enzyme. (572 aa)
EXTL2Exostosin like glycosyltransferase 2. (330 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa)
MGAT2Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (446 aa)
MGAT1Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (399 aa)
GYG1Glycogenin 1. (369 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (486 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (983 aa)
MPPE1Metallophosphoesterase 1. (393 aa)
CCP110Centriolar coiled-coil protein 110. (1009 aa)
XXYLT1Xyloside xylosyltransferase 1. (392 aa)
IMPA1Inositol-1-monophosphatase. (318 aa)
XPNPEP3X-prolyl aminopeptidase 3. (524 aa)
GALNT2Polypeptide N-acetylgalactosaminyltransferase. (585 aa)
ARG1Arginase. (329 aa)
LAP3Leucine aminopeptidase 3. (537 aa)
NUDT16Nudix hydrolase 16. (195 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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