52 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	POMGNT1	Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-). (660 aa)
	DCP2	Decapping mRNA 2. (422 aa)
	XPNPEP1	X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family. (666 aa)
	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent. (377 aa)
	MGAT5B	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B. (792 aa)
	ABL1	Tyrosine-protein kinase. (1150 aa)
	ABL2	Tyrosine-protein kinase. (1160 aa)
	PPEF2	Serine/threonine-protein phosphatase with EF-hands. (752 aa)
	PEPD	Peptidase D. (493 aa)
	DYRK2	Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
	ME3	Malic enzyme. (604 aa)
	FEN1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	ARG2	Arginase. (354 aa)
	FASTKD3	FAST kinase domains 3. (627 aa)
	PPM1M	Protein phosphatase, Mg2+/Mn2+ dependent 1M. (461 aa)
	MGAT5	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase. (780 aa)
	LARGE1	LARGE xylosyl- and glucuronyltransferase 1. (756 aa)
	MTPAP	Mitochondrial poly(A) polymerase. (584 aa)
	TDP2	Tyrosyl-DNA phosphodiesterase 2. (362 aa)
	NPEPL1	Aminopeptidase like 1. (523 aa)
	B4GALT7	Beta-1,4-galactosyltransferase 7. (381 aa)
	B4GALT1	Beta-1,4-galactosyltransferase 1. (400 aa)
	NUDT7	Nudix hydrolase 7. (238 aa)
	WRN	WRN RecQ like helicase. (1406 aa)
	PPM1B	Protein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
	GALNT1	Polypeptide N-acetylgalactosaminyltransferase. (559 aa)
	PIM1	Serine/threonine-protein kinase pim-1; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation and thus providing a selective advantage in tumorigenesis. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression and by phosphorylation and inhibition of proapoptotic proteins (BAD, MAP3K5). Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase of transcriptional activity. The stabilization of MYC exerted by PIM1 might explain partly th [...] (313 aa)
	PRIMPOL	Primase and DNA directed polymerase. (556 aa)
	MRE11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (738 aa)
	PPM1N	Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (423 aa)
	FAM20C	FAM20C golgi associated secretory pathway kinase. (615 aa)
	SOD2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
	PPEF1	Serine/threonine-protein phosphatase with EF-hands. (660 aa)
	ME1	Malic enzyme. (572 aa)
	EXTL2	Exostosin like glycosyltransferase 2. (330 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa)
	MGAT2	Mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (446 aa)
	MGAT1	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (399 aa)
	GYG1	Glycogenin 1. (369 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	GALNT3	Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (486 aa)
	ATP2C1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (983 aa)
	MPPE1	Metallophosphoesterase 1. (393 aa)
	CCP110	Centriolar coiled-coil protein 110. (1009 aa)
	XXYLT1	Xyloside xylosyltransferase 1. (392 aa)
	IMPA1	Inositol-1-monophosphatase. (318 aa)
	XPNPEP3	X-prolyl aminopeptidase 3. (524 aa)
	GALNT2	Polypeptide N-acetylgalactosaminyltransferase. (585 aa)
	ARG1	Arginase. (329 aa)
	LAP3	Leucine aminopeptidase 3. (537 aa)
	NUDT16	Nudix hydrolase 16. (195 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSFCAP00000004739	ENSFCAP00000004918	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.939
ABL1	MRE11	ENSFCAP00000004739	ENSFCAP00000022057	Tyrosine-protein kinase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.466
ABL2	ABL1	ENSFCAP00000004918	ENSFCAP00000004739	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.939
ABL2	MRE11	ENSFCAP00000004918	ENSFCAP00000022057	Tyrosine-protein kinase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.466
ARG1	ARG2	ENSFCAP00000056022	ENSFCAP00000013066	Arginase.	Arginase.	0.910
ARG2	ARG1	ENSFCAP00000013066	ENSFCAP00000056022	Arginase.	Arginase.	0.910
B4GALT1	EXTL2	ENSFCAP00000017809	ENSFCAP00000041627	Beta-1,4-galactosyltransferase 1.	Exostosin like glycosyltransferase 2.	0.479
B4GALT1	GALNT2	ENSFCAP00000017809	ENSFCAP00000053792	Beta-1,4-galactosyltransferase 1.	Polypeptide N-acetylgalactosaminyltransferase.	0.580
B4GALT1	MGAT5	ENSFCAP00000017809	ENSFCAP00000014617	Beta-1,4-galactosyltransferase 1.	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase.	0.448
B4GALT1	MGAT5B	ENSFCAP00000017809	ENSFCAP00000003906	Beta-1,4-galactosyltransferase 1.	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B.	0.942
B4GALT1	POMGNT1	ENSFCAP00000017809	ENSFCAP00000000513	Beta-1,4-galactosyltransferase 1.	Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-).	0.922
EXTL2	B4GALT1	ENSFCAP00000041627	ENSFCAP00000017809	Exostosin like glycosyltransferase 2.	Beta-1,4-galactosyltransferase 1.	0.479
FEN1	GYG1	ENSFCAP00000012693	ENSFCAP00000061984	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Glycogenin 1.	0.473
FEN1	MRE11	ENSFCAP00000012693	ENSFCAP00000022057	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.956
FEN1	WRN	ENSFCAP00000012693	ENSFCAP00000018012	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	WRN RecQ like helicase.	0.998
GALNT1	GALNT2	ENSFCAP00000019519	ENSFCAP00000053792	Polypeptide N-acetylgalactosaminyltransferase.	Polypeptide N-acetylgalactosaminyltransferase.	0.472
GALNT1	LAP3	ENSFCAP00000019519	ENSFCAP00000057261	Polypeptide N-acetylgalactosaminyltransferase.	Leucine aminopeptidase 3.	0.454
GALNT1	MGAT5	ENSFCAP00000019519	ENSFCAP00000014617	Polypeptide N-acetylgalactosaminyltransferase.	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase.	0.418
GALNT2	B4GALT1	ENSFCAP00000053792	ENSFCAP00000017809	Polypeptide N-acetylgalactosaminyltransferase.	Beta-1,4-galactosyltransferase 1.	0.580
GALNT2	GALNT1	ENSFCAP00000053792	ENSFCAP00000019519	Polypeptide N-acetylgalactosaminyltransferase.	Polypeptide N-acetylgalactosaminyltransferase.	0.472