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RFLNB RFLNB ENPP1 ENPP1 AHSG AHSG ATRAID ATRAID ACVR2B ACVR2B COMP COMP BGLAP BGLAP GPM6B GPM6B BMP4 BMP4 LTBP3 LTBP3 FGF23 FGF23 TMEM119 TMEM119 SOX9 SOX9 ANO6 ANO6 ACTN3 ACTN3 TXLNG TXLNG PTH PTH WNT10B WNT10B OSR2 OSR2 SLC8A1 SLC8A1 BMP2K BMP2K PKDCC PKDCC HIF1A HIF1A TGFB1 TGFB1 ZMPSTE24 ZMPSTE24 ATP2B1 ATP2B1 ADRB2 ADRB2 GATA1 GATA1 NOTUM NOTUM OMD OMD ANKH ANKH TFAP2A TFAP2A P2RX7 P2RX7 FZD9 FZD9 ALOX5 ALOX5 CYP27C1 CYP27C1 BMPR2 BMPR2 TGFB3 TGFB3 LTF LTF CYP27B1 CYP27B1 ECM1 ECM1 CCN1 CCN1 PTK2B PTK2B MATN1 MATN1 OSR1 OSR1 PTN PTN BMPR1A BMPR1A BMP6 BMP6 RFLNA RFLNA SRGN SRGN MEF2C MEF2C BMP2 BMP2 NBR1 NBR1 BCOR BCOR DDR2 DDR2 ISG15 ISG15 TENT5A TENT5A ACVR2A ACVR2A MGP MGP BMPR1B BMPR1B SLC8A3 SLC8A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFLNBRefilin B. (218 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa)
AHSGAlpha 2-HS glycoprotein. (371 aa)
ATRAIDEGF-like domain-containing protein. (229 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
COMPCartilage oligomeric matrix protein. (804 aa)
BGLAPOsteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. (102 aa)
GPM6BGlycoprotein M6B. (397 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1302 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (245 aa)
TMEM119Transmembrane protein 119. (279 aa)
SOX9SRY-box transcription factor 9. (511 aa)
ANO6Anoctamin. (932 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (933 aa)
TXLNGTaxilin gamma. (591 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
OSR2Odd-skipped related transciption factor 2. (312 aa)
SLC8A1Sodium/calcium exchanger 1; Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation- contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels r [...] (973 aa)
BMP2KBMP2 inducible kinase. (1141 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (494 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
GATA1GATA binding protein 1. (413 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (500 aa)
OMDOsteomodulin. (415 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (492 aa)
TFAP2ATranscription factor AP-2 alpha. (437 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
ALOX5Arachidonate 5-lipoxygenase. (745 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (580 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
ECM1Extracellular matrix protein 1. (562 aa)
CCN1Cellular communication network factor 1. (382 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
MATN1Matrilin 1. (539 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
PTNPleiotrophin. (179 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
BMP6Bone morphogenetic protein 6. (502 aa)
RFLNARefilin A. (209 aa)
SRGNSerglycin. (164 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
NBR1NBR1 autophagy cargo receptor. (968 aa)
BCORBCL6 corepressor. (1802 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (866 aa)
ISG15ISG15 ubiquitin like modifier. (157 aa)
TENT5ATerminal nucleotidyltransferase 5A. (448 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (215 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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