STRINGSTRING
VWC2L VWC2L SFRP1 SFRP1 SPART SPART HIPK2 HIPK2 TNFAIP6 TNFAIP6 TWSG1 TWSG1 SKI SKI NOTCH1 NOTCH1 SMURF2 SMURF2 LOC101084379 LOC101084379 LEMD3 LEMD3 FBN1 FBN1 HTRA3 HTRA3 SMURF1 SMURF1 SORL1 SORL1 SMAD6 SMAD6 CRIM1 CRIM1 CHRD CHRD LRP2 LRP2 LEMD2 LEMD2 ABL1 ABL1 NANOG NANOG BMPER BMPER WNT1 WNT1 CHRDL2 CHRDL2 ENSFCAP00000058884 ENSFCAP00000058884 FSTL3 FSTL3 TOB1 TOB1 DLX1 DLX1 CER1 CER1 PPM1A PPM1A HJV HJV VWC2 VWC2 NOG NOG GREM2 GREM2 SOST SOST SKOR2 SKOR2 SKOR1 SKOR1 SMAD7 SMAD7 BAMBI BAMBI TRIM33 TRIM33 CHRDL1 CHRDL1 TMPRSS6 TMPRSS6 SFRP2 SFRP2 SOSTDC1 SOSTDC1 SKIL SKIL NBL1 NBL1 CTDSPL2 CTDSPL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWC2LVon Willebrand factor C domain containing 2 like. (232 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
SPARTSpartin. (672 aa)
HIPK2Homeodomain interacting protein kinase 2. (1222 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
SKISKI proto-oncogene. (730 aa)
NOTCH1Notch receptor 1. (2543 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
LOC101084379Homeobox domain-containing protein. (290 aa)
LEMD3LEM domain containing 3. (915 aa)
FBN1Fibrillin 1. (2871 aa)
HTRA3HtrA serine peptidase 3. (453 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
SORL1Sortilin related receptor 1. (2211 aa)
SMAD6Mothers against decapentaplegic homolog. (497 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1037 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (954 aa)
LRP2LDL receptor related protein 2. (4646 aa)
LEMD2LEM domain containing 2. (566 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
NANOGNanog homeobox. (311 aa)
BMPERBMP binding endothelial regulator. (685 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CHRDL2Chordin like 2. (440 aa)
ENSFCAP00000058884Protein kinase domain-containing protein. (375 aa)
FSTL3Follistatin like 3. (364 aa)
TOB1Transducer of ERBB2, 1. (345 aa)
DLX1Distal-less homeobox 1. (255 aa)
CER1Cerberus 1, DAN family BMP antagonist. (270 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (486 aa)
HJVHemojuvelin BMP co-receptor. (427 aa)
VWC2Von Willebrand factor C domain containing 2. (333 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (187 aa)
SOSTSclerostin. (212 aa)
SKOR2SKI family transcriptional corepressor 2. (1010 aa)
SKOR1SKI family transcriptional corepressor 1. (963 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
TRIM33Tripartite motif containing 33. (1127 aa)
CHRDL1Chordin like 1. (602 aa)
TMPRSS6Transmembrane serine protease 6. (882 aa)
SFRP2Secreted frizzled related protein 2. (385 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
SKILSKI like proto-oncogene. (686 aa)
NBL1NBL1, DAN family BMP antagonist. (176 aa)
CTDSPL2CTD small phosphatase like 2. (466 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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