(31 nodes) Collagen catabolic process network (Felis catus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MMP21	Matrix metallopeptidase 21. (560 aa)
	MMP13	Matrix metallopeptidase 13. (470 aa)
	MMP15	Matrix metallopeptidase 15. (678 aa)
	MMP14	Matrix metallopeptidase 14. (582 aa)
	PEPD	Peptidase D. (493 aa)
	MRC2	Mannose receptor C type 2. (1482 aa)
	MMP12	Matrix metallopeptidase 12. (470 aa)
	RETREG2	Reticulophagy regulator family member 2. (546 aa)
	RETREG3	Reticulophagy regulator family member 3. (466 aa)
	MMP19	Matrix metallopeptidase 19. (513 aa)
	MMP9	Matrix metallopeptidase 9. (705 aa)
	MMP11	Matrix metallopeptidase 11. (488 aa)
	MMP7	Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase; Belongs to the peptidase M10A family. (267 aa)
	MMP20	Matrix metallopeptidase 20. (483 aa)
	MMP27	Matrix metallopeptidase 27. (510 aa)
	MMP8	Matrix metallopeptidase 8. (476 aa)
	MMP1	Matrix metallopeptidase 1. (471 aa)
	MMP3	Matrix metallopeptidase 3. (478 aa)
	MMP10	Matrix metallopeptidase 10. (478 aa)
	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif 2. (1211 aa)
	MMP17	Matrix metallopeptidase 17. (643 aa)
	MMP24	Matrix metallopeptidase 24. (630 aa)
	MMP16	Matrix metallopeptidase 16. (607 aa)
	PDP	Cathepsin L1; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (332 aa)
	MMP25	ZnMc domain-containing protein. (562 aa)
	ENSFCAP00000029537	ZnMc domain-containing protein. (172 aa)
	MMP28	Matrix metallopeptidase 28. (520 aa)
	CTSV	Cathepsin V; Belongs to the peptidase C1 family. (333 aa)
	MMP2	Matrix metallopeptidase 2. (661 aa)
	MMP23B	Matrix metallopeptidase 23B. (391 aa)
	LOC101083957	ZnMc domain-containing protein. (442 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTSV	MMP13	ENSFCAP00000036179	ENSFCAP00000000108	Cathepsin V; Belongs to the peptidase C1 family.	Matrix metallopeptidase 13.	0.769
CTSV	MMP7	ENSFCAP00000036179	ENSFCAP00000014641	Cathepsin V; Belongs to the peptidase C1 family.	Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase; Belongs to the peptidase M10A family.	0.786
ENSFCAP00000029537	MMP13	ENSFCAP00000029537	ENSFCAP00000000108	ZnMc domain-containing protein.	Matrix metallopeptidase 13.	0.492
LOC101083957	MMP10	ENSFCAP00000061744	ENSFCAP00000014650	ZnMc domain-containing protein.	Matrix metallopeptidase 10.	0.403
LOC101083957	MMP11	ENSFCAP00000061744	ENSFCAP00000014197	ZnMc domain-containing protein.	Matrix metallopeptidase 11.	0.473
LOC101083957	MMP12	ENSFCAP00000061744	ENSFCAP00000010202	ZnMc domain-containing protein.	Matrix metallopeptidase 12.	0.592
LOC101083957	MMP13	ENSFCAP00000061744	ENSFCAP00000000108	ZnMc domain-containing protein.	Matrix metallopeptidase 13.	0.451
LOC101083957	MMP14	ENSFCAP00000061744	ENSFCAP00000006156	ZnMc domain-containing protein.	Matrix metallopeptidase 14.	0.476
LOC101083957	MMP15	ENSFCAP00000061744	ENSFCAP00000002480	ZnMc domain-containing protein.	Matrix metallopeptidase 15.	0.422
LOC101083957	MMP2	ENSFCAP00000061744	ENSFCAP00000040098	ZnMc domain-containing protein.	Matrix metallopeptidase 2.	0.683
LOC101083957	MMP20	ENSFCAP00000061744	ENSFCAP00000014642	ZnMc domain-containing protein.	Matrix metallopeptidase 20.	0.657
LOC101083957	MMP3	ENSFCAP00000061744	ENSFCAP00000014646	ZnMc domain-containing protein.	Matrix metallopeptidase 3.	0.586
LOC101083957	MMP7	ENSFCAP00000061744	ENSFCAP00000014641	ZnMc domain-containing protein.	Matrilysin; Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase; Belongs to the peptidase M10A family.	0.531
LOC101083957	MMP9	ENSFCAP00000061744	ENSFCAP00000012997	ZnMc domain-containing protein.	Matrix metallopeptidase 9.	0.613
MMP1	MMP10	ENSFCAP00000014645	ENSFCAP00000014650	Matrix metallopeptidase 1.	Matrix metallopeptidase 10.	0.402
MMP1	MMP11	ENSFCAP00000014645	ENSFCAP00000014197	Matrix metallopeptidase 1.	Matrix metallopeptidase 11.	0.455
MMP1	MMP12	ENSFCAP00000014645	ENSFCAP00000010202	Matrix metallopeptidase 1.	Matrix metallopeptidase 12.	0.582
MMP1	MMP13	ENSFCAP00000014645	ENSFCAP00000000108	Matrix metallopeptidase 1.	Matrix metallopeptidase 13.	0.453
MMP1	MMP14	ENSFCAP00000014645	ENSFCAP00000006156	Matrix metallopeptidase 1.	Matrix metallopeptidase 14.	0.459
MMP1	MMP2	ENSFCAP00000014645	ENSFCAP00000040098	Matrix metallopeptidase 1.	Matrix metallopeptidase 2.	0.968