Your Input: | |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | KRT84 | Keratin 84; Belongs to the intermediate filament family. (601 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa) |
| | TMEM100 | Transmembrane protein 100. (134 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | STAT5B | Signal transducer and activator of transcription. (786 aa) |
| | FOXJ2 | Forkhead box J2. (572 aa) |
| | KLF7 | Kruppel like factor 7. (301 aa) |
| | NXNL2 | Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (623 aa) |
| | ERRFI1 | ERBB receptor feedback inhibitor 1. (460 aa) |
| | GRHL2 | Grainyhead like transcription factor 2. (625 aa) |
| | FOXJ1 | Forkhead box J1. (417 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (444 aa) |
| | PAX6 | Paired box 6. (437 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | GRHL1 | Grainyhead like transcription factor 1. (618 aa) |
| | FOXN1 | Forkhead box N1. (646 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (261 aa) |
| | ABCA12 | ATP binding cassette subfamily A member 12. (2595 aa) |
| | PTCH2 | Patched 2. (1207 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (749 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (443 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (624 aa) |
| | PRKCH | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa) |
| | S1PR2 | Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (362 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (580 aa) |
| | FRZB | Frizzled related protein. (324 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | NCOA3 | Nuclear receptor coactivator. (1412 aa) |
| | PROM1 | Prominin 1. (855 aa) |
| | CDH5-2 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (314 aa) |
| | KRAS | Uncharacterized protein. (380 aa) |
| | PRKX | Uncharacterized protein. (416 aa) |
| | KDF1 | Keratinocyte differentiation factor 1. (397 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | HOXA7 | Homeobox A7. (234 aa) |
| | NOTCH1 | Notch receptor 1. (2543 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | OSR1 | Odd-skipped related transcription factor 1. (267 aa) |
| | VDR | Vitamin D receptor. (441 aa) |
| | TRIM16 | Uncharacterized protein. (528 aa) |
| | MYCL | MYCL proto-oncogene, bHLH transcription factor. (394 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | CD109 | CD109 molecule. (1446 aa) |
| | VCL | Vinculin. (1066 aa) |
| | ADD1 | Adducin 1. (761 aa) |
| | BMP6 | Bone morphogenetic protein 6. (502 aa) |
| | SRSF6 | Serine and arginine rich splicing factor 6. (344 aa) |
| | ZDHHC21 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (299 aa) |
| | KRT36 | IF rod domain-containing protein; Belongs to the intermediate filament family. (467 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | MAFG | MAF bZIP transcription factor G. (162 aa) |
| | ZBED2 | Zinc finger BED-type containing 2. (218 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1125 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) |
| | GDNF | Glial cell derived neurotrophic factor. (211 aa) |
| | FST | Follistatin. (423 aa) |
| | LIF | LIF interleukin 6 family cytokine. (204 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa) |
| | PAX8 | Paired box 8. (620 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa) |
| | AHI1 | Abelson helper integration site 1. (951 aa) |
| | LHX1 | LIM homeobox 1. (406 aa) |
| | ATOH1 | Atonal bHLH transcription factor 1. (356 aa) |
| | BTG1 | BTG anti-proliferation factor 1. (171 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (166 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | F11R | Junctional adhesion molecule A; Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation. (Microbial infection) In case of orthoreovirus infection, serves as rec [...] (378 aa) |
| | MACROH2A2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (264 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (760 aa) |
| | PTCH1 | Patched 1. (1451 aa) |
| | SOX9 | SRY-box transcription factor 9. (511 aa) |
| | CDH5 | Uncharacterized protein. (402 aa) |
| | ZFP36 | ZFP36 ring finger protein. (513 aa) |
| | BAD | BCL2 associated agonist of cell death. (273 aa) |
| | TBX3 | T-box transcription factor 3. (745 aa) |
| | COMMD5 | COMM domain containing 5. (224 aa) |
| | YAP1 | Yes associated protein 1. (498 aa) |
| | APOLD1 | Apolipoprotein L domain containing 1. (279 aa) |
| | NFE2L1 | Nuclear factor, erythroid 2 like 1. (880 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | PROC | Vitamin K-dependent protein C; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. (555 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (678 aa) |
| | ENSFCAP00000052961 | LRAT domain-containing protein. (162 aa) |
| | AJAP1 | Adherens junctions associated protein 1. (431 aa) |
| | MAFF | MAF bZIP transcription factor F. (178 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (355 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | AHI1-2 | Uncharacterized protein. (55 aa) |
| | ASCL1 | Achaete-scute family bHLH transcription factor 1. (246 aa) |
| | NKX6-3 | NK6 homeobox 3. (268 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1287 aa) |
| | PAX4 | Paired box 4. (351 aa) |
| | ETV4 | ETS variant 4. (488 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa) |
| | NUMA1 | Nuclear mitotic apparatus protein 1. (2135 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (252 aa) |
| | ETV2 | ETS variant 2. (249 aa) |
