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ENG ENG NEK10 NEK10 ERRFI1 ERRFI1 RAP2B RAP2B ADIPOQ ADIPOQ NLRP12 NLRP12 PDGFB PDGFB RAD50 RAD50 DDX3X DDX3X TESK1 TESK1 RAP2C RAP2C JUN JUN MRE11 MRE11 PDGFA PDGFA MVP MVP GPNMB GPNMB IMPACT IMPACT CAV1 CAV1 TOM1L1 TOM1L1 RAP2A RAP2A VEGFA VEGFA MOB1B MOB1B NBN NBN PDGFD PDGFD EEF2K EEF2K LOC102902092 LOC102902092 RASSF2 RASSF2 PTPRC PTPRC PDGFC PDGFC SSRP1 SSRP1 ENPP1 ENPP1 ENSFCAP00000061258 ENSFCAP00000061258
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENGEndoglin. (654 aa)
NEK10NIMA related kinase 10. (1173 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (460 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (283 aa)
NLRP12NLR family pyrin domain containing 12. (1034 aa)
PDGFBPlatelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa)
RAD50Zinc-hook domain-containing protein. (1311 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (662 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (738 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
MVPMajor vault protein. (892 aa)
GPNMBGlycoprotein nmb. (568 aa)
IMPACTImpact RWD domain protein. (331 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein. (521 aa)
RAP2ARAP2A, member of RAS oncogene family. (183 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (450 aa)
MOB1BMOB kinase activator 1B. (221 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (783 aa)
PDGFDPlatelet derived growth factor D. (380 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
LOC102902092NACHT domain-containing protein. (1031 aa)
RASSF2Ras association domain family member 2. (375 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
SSRP1Tankyrase 1 binding protein 1. (1753 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa)
ENSFCAP00000061258Uncharacterized protein. (170 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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