STRINGSTRING
HOXA2 HOXA2 CREB1 CREB1 TBX2 TBX2 RET RET PTK7 PTK7 TMEM161A TMEM161A RXRG RXRG GDAP1 GDAP1 NDUFA13 NDUFA13 TIE1 TIE1 LOC101084379 LOC101084379 PTK2B PTK2B TWF2 TWF2 CDKN2D CDKN2D OSR1 OSR1 TRIM16 TRIM16 LYN LYN GATA6 GATA6 BRINP3 BRINP3 DNAAF2 DNAAF2 ATM ATM AQP1 AQP1 AQP3 AQP3 IGFBP2 IGFBP2 SETX SETX BRINP1 BRINP1 BRINP2 BRINP2 ALDH1A2 ALDH1A2 GSK3B GSK3B LOC101085801 LOC101085801 CYP26B1 CYP26B1 ENSFCAP00000045932 ENSFCAP00000045932 SOX9 SOX9 RXRA RXRA YAP1 YAP1 RARG RARG OVCA2 OVCA2 HSD17B2 HSD17B2 BHMG1 BHMG1 STRA8 STRA8 ASCL1 ASCL1 CTSH CTSH ADNP2 ADNP2 TEAD2 TEAD2 NANOG NANOG SNW1 SNW1 ASXL1 ASXL1 ACER2 ACER2 GDAP2 GDAP2 ABL2 ABL2 LOC111556172 LOC111556172 HTRA2 HTRA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXA2Homeobox A2. (376 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
TBX2T-box transcription factor 2. (713 aa)
RETRet proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1138 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
TMEM161ATransmembrane protein 161A. (511 aa)
RXRGRetinoid X receptor gamma. (463 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1137 aa)
LOC101084379Homeobox domain-containing protein. (290 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
OSR1Odd-skipped related transcription factor 1. (267 aa)
TRIM16Uncharacterized protein. (528 aa)
LYNTyrosine-protein kinase. (526 aa)
GATA6GATA binding protein 6. (646 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (825 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
IGFBP2Insulin like growth factor binding protein 2. (330 aa)
SETXSenataxin. (2669 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (784 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
LOC101085801Uncharacterized protein. (467 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
ENSFCAP00000045932Uncharacterized protein. (123 aa)
SOX9SRY-box transcription factor 9. (511 aa)
RXRARetinoid X receptor alpha. (654 aa)
YAP1Yes associated protein 1. (498 aa)
RARGRetinoic acid receptor gamma. (459 aa)
OVCA2OVCA2 serine hydrolase domain containing. (268 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (591 aa)
STRA8Stimulated by retinoic acid 8. (376 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (246 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (572 aa)
ADNP2ADNP homeobox 2. (1223 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
NANOGNanog homeobox. (311 aa)
SNW1SNW domain containing 1. (570 aa)
ASXL1ASXL transcriptional regulator 1. (1545 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
GDAP2Ganglioside induced differentiation associated protein 2. (497 aa)
ABL2Tyrosine-protein kinase. (1160 aa)
LOC111556172Uncharacterized protein. (536 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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