52 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXA2	Homeobox A2. (376 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	TBX2	T-box transcription factor 2. (713 aa)
	RET	Ret proto-oncogene; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1138 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
	TMEM161A	Transmembrane protein 161A. (511 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	GDAP1	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
	NDUFA13	NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
	TIE1	Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1137 aa)
	LOC101084379	Homeobox domain-containing protein. (290 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
	TWF2	Twinfilin actin binding protein 2. (349 aa)
	CDKN2D	Cyclin dependent kinase inhibitor 2D. (166 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	TRIM16	Uncharacterized protein. (528 aa)
	LYN	Tyrosine-protein kinase. (526 aa)
	GATA6	GATA binding protein 6. (646 aa)
	BRINP3	BMP/retinoic acid inducible neural specific 3. (766 aa)
	DNAAF2	Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (825 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
	AQP3	Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
	IGFBP2	Insulin like growth factor binding protein 2. (330 aa)
	SETX	Senataxin. (2669 aa)
	BRINP1	BMP/retinoic acid inducible neural specific 1. (761 aa)
	BRINP2	BMP/retinoic acid inducible neural specific 2. (784 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
	GSK3B	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
	LOC101085801	Uncharacterized protein. (467 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	ENSFCAP00000045932	Uncharacterized protein. (123 aa)
	SOX9	SRY-box transcription factor 9. (511 aa)
	RXRA	Retinoid X receptor alpha. (654 aa)
	YAP1	Yes associated protein 1. (498 aa)
	RARG	Retinoic acid receptor gamma. (459 aa)
	OVCA2	OVCA2 serine hydrolase domain containing. (268 aa)
	HSD17B2	Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
	BHMG1	Basic helix-loop-helix and HMG-box containing 1. (591 aa)
	STRA8	Stimulated by retinoic acid 8. (376 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (246 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (572 aa)
	ADNP2	ADNP homeobox 2. (1223 aa)
	TEAD2	TEA domain transcription factor 2. (451 aa)
	NANOG	Nanog homeobox. (311 aa)
	SNW1	SNW domain containing 1. (570 aa)
	ASXL1	ASXL transcriptional regulator 1. (1545 aa)
	ACER2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	GDAP2	Ganglioside induced differentiation associated protein 2. (497 aa)
	ABL2	Tyrosine-protein kinase. (1160 aa)
	LOC111556172	Uncharacterized protein. (536 aa)
	HTRA2	HtrA serine peptidase 2. (458 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL2	ATM	ENSFCAP00000004918	ENSFCAP00000025928	Tyrosine-protein kinase.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.757
ABL2	YAP1	ENSFCAP00000004918	ENSFCAP00000049727	Tyrosine-protein kinase.	Yes associated protein 1.	0.513
ALDH1A2	CYP26B1	ENSFCAP00000041980	ENSFCAP00000045334	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.942
ALDH1A2	STRA8	ENSFCAP00000041980	ENSFCAP00000055413	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Stimulated by retinoic acid 8.	0.420
AQP1	AQP3	ENSFCAP00000029541	ENSFCAP00000029966	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.576
AQP3	AQP1	ENSFCAP00000029966	ENSFCAP00000029541	Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.576
ASCL1	CREB1	ENSFCAP00000057051	ENSFCAP00000007617	Achaete-scute family bHLH transcription factor 1.	cAMP responsive element binding protein 1.	0.626
ASCL1	SOX9	ENSFCAP00000057051	ENSFCAP00000045943	Achaete-scute family bHLH transcription factor 1.	SRY-box transcription factor 9.	0.616
ATM	ABL2	ENSFCAP00000025928	ENSFCAP00000004918	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Tyrosine-protein kinase.	0.757
ATM	GSK3B	ENSFCAP00000025928	ENSFCAP00000043679	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.416
CREB1	ASCL1	ENSFCAP00000007617	ENSFCAP00000057051	cAMP responsive element binding protein 1.	Achaete-scute family bHLH transcription factor 1.	0.626
CREB1	GSK3B	ENSFCAP00000007617	ENSFCAP00000043679	cAMP responsive element binding protein 1.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.733
CYP26B1	ALDH1A2	ENSFCAP00000045334	ENSFCAP00000041980	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	0.942
CYP26B1	RARG	ENSFCAP00000045334	ENSFCAP00000051056	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Retinoic acid receptor gamma.	0.410
CYP26B1	SOX9	ENSFCAP00000045334	ENSFCAP00000045943	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	SRY-box transcription factor 9.	0.470
CYP26B1	STRA8	ENSFCAP00000045334	ENSFCAP00000055413	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Stimulated by retinoic acid 8.	0.633
ENSFCAP00000045932	LOC101085801	ENSFCAP00000045932	ENSFCAP00000043848	Uncharacterized protein.	Uncharacterized protein.	0.777
ENSFCAP00000045932	RARG	ENSFCAP00000045932	ENSFCAP00000051056	Uncharacterized protein.	Retinoic acid receptor gamma.	0.579
ENSFCAP00000045932	RXRG	ENSFCAP00000045932	ENSFCAP00000009995	Uncharacterized protein.	Retinoid X receptor gamma.	0.682
GATA6	LOC101084379	ENSFCAP00000023729	ENSFCAP00000018204	GATA binding protein 6.	Homeobox domain-containing protein.	0.674