STRINGSTRING
TGFB1 TGFB1 TGFB3 TGFB3 NCOA2 NCOA2 UBE3A UBE3A CAV1 CAV1 TGFB2 TGFB2 BAD BAD CSN1S1 CSN1S1 YAP1 YAP1 NR1H3 NR1H3 ABHD2 ABHD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
NCOA2Nuclear receptor coactivator. (1470 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (834 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
BADBCL2 associated agonist of cell death. (273 aa)
CSN1S1Casein alpha s1. (183 aa)
YAP1Yes associated protein 1. (498 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (498 aa)
ABHD2Abhydrolase domain containing 2. (477 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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