STRINGSTRING
USF1 USF1 ANXA1 ANXA1 ENPP1 ENPP1 WDTC1 WDTC1 ESRRB ESRRB UCN3 UCN3 LY6G5B LY6G5B UBE3A UBE3A GATA6 GATA6 TMF1 TMF1 ESRRA ESRRA RAB8B RAB8B SLC2A8 SLC2A8 ESR1 ESR1 EPHA8 EPHA8 SSTR4 SSTR4 NOTCH1 NOTCH1 RXFP1 RXFP1 NR3C1 NR3C1 PARP6 PARP6 CAV2 CAV2 NCOA2 NCOA2 DDIT4 DDIT4 SYAP1 SYAP1 IRS1 IRS1 CASP9 CASP9 RAB12 RAB12 M3WTU8_FELCA M3WTU8_FELCA PDK4 PDK4 NR3C2 NR3C2 INSRR INSRR RAMP1 RAMP1 LOC101081229 LOC101081229 SP1 SP1 LPIN2 LPIN2 MSTN MSTN IGF1R IGF1R APPL2 APPL2 GLP2R GLP2R DENND4C DENND4C JAK1 JAK1 PDPK1 PDPK1 STAT5B STAT5B STAT3 STAT3 GHRHR GHRHR EPRS1 EPRS1 MAS1 MAS1 POU4F2 POU4F2 SLC2A4 SLC2A4 KIT KIT DNAI1 DNAI1 GH1 GH1 DDX5 DDX5 AKT3 AKT3 PRKCD PRKCD PTPN1 PTPN1 CST11 CST11 DAXX DAXX TRIM24 TRIM24 SSTR5 SSTR5 CACNA1H CACNA1H TTC6 TTC6 KAT2B KAT2B SSTR2 SSTR2 AKT1 AKT1 MYOD1 MYOD1 ACSL1 ACSL1 AHCYL1 AHCYL1 SCNN1G SCNN1G PPARA PPARA PARP1 PARP1 GLP1R GLP1R LOC111556172 LOC111556172 AR AR JAK3 JAK3 SLC5A5 SLC5A5 CSNK2B CSNK2B P2RY4 P2RY4 NEDD4 NEDD4 ACACB ACACB MKKS MKKS BBS2 BBS2 UCP1 UCP1 RAMP2 RAMP2 LHCGR LHCGR NPAS4 NPAS4 TYK2 TYK2 SSTR1 SSTR1 PHIP PHIP PDK2 PDK2 PADI2 PADI2 RARB RARB FBXO32 FBXO32 KDM3A KDM3A CSRP3 CSRP3 RXRG RXRG GATA1 GATA1 SLIT3 SLIT3 UGCG UGCG PIK3R1 PIK3R1 GPLD1 GPLD1 UBR5 UBR5 GHSR GHSR ZMIZ1 ZMIZ1 NR4A2 NR4A2 GRB10 GRB10 AUNIP AUNIP SOGA1 SOGA1 TFPI TFPI ADIPOQ ADIPOQ AGTR2 AGTR2 EBI3 EBI3 STAT6 STAT6 EDN1 EDN1 NCOA3 NCOA3 SLC30A10 SLC30A10 SMARCC1 SMARCC1 OTOP1 OTOP1 GCGR GCGR TBC1D4 TBC1D4 ADCY6 ADCY6 NR4A1 NR4A1 PCK1 PCK1 AGTR1 AGTR1 IRS4 IRS4 FSHR FSHR SHC1 SHC1 SLC39A14 SLC39A14 PHB2 PHB2 LOC101100432 LOC101100432 OSTN OSTN BRD8 BRD8 M3X5D6_FELCA M3X5D6_FELCA ZDHHC7 ZDHHC7 HNF4G HNF4G RPS6KB1 RPS6KB1 URI1 URI1 LATS1 LATS1 GSK3A GSK3A GOT1 GOT1 CPEB2 CPEB2 ENSFCAP00000060514 ENSFCAP00000060514 LATS2 LATS2 INPP5K INPP5K ABHD2 ABHD2 AKT2 AKT2 GRB14 GRB14 GNG2 GNG2 SLC27A4 SLC27A4 TNFSF4 TNFSF4 CTSH CTSH ESRRG ESRRG INSIG2 INSIG2 ARID5A ARID5A CALCOCO1 CALCOCO1 ADTRP ADTRP STAT5A STAT5A ENSFCAP00000055099 ENSFCAP00000055099 CA2 CA2 EIF4EBP2 EIF4EBP2 PPARGC1B PPARGC1B HNRNPU HNRNPU NDEL1 NDEL1 ANKRD26 ANKRD26 RAB31 RAB31 RAB10 RAB10 NKX3-1 NKX3-1 TRIP4 TRIP4 SLC27A1 SLC27A1 NR1H3 NR1H3 SLC2A1 SLC2A1 RARRES2 RARRES2 BMP4 BMP4 RARG RARG RAB15 RAB15 PPARG PPARG RBFOX2 RBFOX2 RAB13 RAB13 DAXX-2 DAXX-2 LOC101097790 LOC101097790 BCAS3 BCAS3 ACTN2 ACTN2 YAP1 YAP1 JAK2 JAK2 PGR PGR RXRA RXRA NR5A1 NR5A1 MGARP MGARP PELP1 PELP1 RELA RELA NR4A3 NR4A3 YWHAH YWHAH ZNF106 ZNF106 ZFP36 ZFP36 C2CD5 C2CD5 STXBP4 STXBP4 PCK2 PCK2 IRS2 IRS2 PIK3R3 PIK3R3 CRHR2 CRHR2 ENSFCAP00000045932 ENSFCAP00000045932 PGF PGF ZFP36L2 ZFP36L2 SOST SOST ARID1A ARID1A UBE2L3 UBE2L3 PKLR PKLR MED1 MED1 ENSFCAP00000044386 ENSFCAP00000044386 LOC101085801 LOC101085801 PID1 PID1 GPER1 GPER1 GSK3B GSK3B PIK3R2 PIK3R2 PTPN2 PTPN2 WT1 WT1 EIF4E EIF4E WBP2 WBP2 ESR2 ESR2 PHB PHB RXFP2 RXFP2 NCOA1 NCOA1 EFNA5 EFNA5 WNT10B WNT10B REST REST PKM PKM XBP1 XBP1 RAMP3 RAMP3 CRHR1 CRHR1 INSIG1 INSIG1 SRC SRC EDNRA EDNRA TFAP4 TFAP4 INHBB INHBB SLIT2 SLIT2 NR5A2 NR5A2 UMODL1 UMODL1 LEPR LEPR FOXO1 FOXO1 APC APC CRADD CRADD PTPRA PTPRA PAX8 PAX8 TRIB3 TRIB3 LPIN1 LPIN1 CEP170 CEP170 RHOQ RHOQ PRKCE PRKCE RARA RARA TRARG1 TRARG1 ACACA ACACA PTGER4 PTGER4 SAFB SAFB SFRP1 SFRP1 PRKAA2 PRKAA2 CAPN10 CAPN10 APPL1 APPL1 BCAR3 BCAR3 BBS4 BBS4 LEP LEP OCSTAMP OCSTAMP ASIP ASIP SMYD3 SMYD3 FOXO4 FOXO4 AGRP AGRP NCOA5 NCOA5 IGFBP2 IGFBP2 MEF2C MEF2C INSR INSR THRB THRB PTPN11 PTPN11 AQP1 AQP1 CAV1 CAV1 LPIN3 LPIN3 TSHR TSHR SRA1 SRA1 DDX17 DDX17 SIRT1 SIRT1 PTGFR PTGFR PPARD PPARD P2RY6 P2RY6 PRLR PRLR ENSFCAP00000026456 ENSFCAP00000026456 TRH TRH SH2B2 SH2B2 PRKCI PRKCI PAQR8 PAQR8 PRKAA1 PRKAA1 RB1 RB1 NR1D2 NR1D2 CRHBP CRHBP SFR1 SFR1 ADIPOR2 ADIPOR2 ZFP36L1 ZFP36L1 GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USF1Upstream transcription factor 1. (444 aa)
ANXA1Annexin. (407 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa)
WDTC1WD and tetratricopeptide repeats 1. (700 aa)
ESRRBEstrogen related receptor beta. (454 aa)
UCN3Urocortin 3. (167 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (216 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (834 aa)
GATA6GATA binding protein 6. (646 aa)
TMF1TATA element modulatory factor 1. (1093 aa)
ESRRAEstrogen related receptor alpha. (506 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
SLC2A8Solute carrier family 2 member 8. (315 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
EPHA8EPH receptor A8. (1003 aa)
SSTR4Somatostatin receptor 4; Belongs to the G-protein coupled receptor 1 family. (387 aa)
NOTCH1Notch receptor 1. (2543 aa)
RXFP1Relaxin family peptide receptor 1. (785 aa)
NR3C1Uncharacterized protein. (843 aa)
PARP6Poly [ADP-ribose] polymerase. (630 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (262 aa)
NCOA2Nuclear receptor coactivator. (1470 aa)
DDIT4DNA damage inducible transcript 4. (231 aa)
SYAP1Synapse associated protein 1. (358 aa)
IRS1Insulin receptor substrate 1. (1234 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (451 aa)
RAB12RAB12, member RAS oncogene family. (339 aa)
M3WTU8_FELCAUncharacterized protein. (84 aa)
PDK4Protein-serine/threonine kinase. (412 aa)
NR3C2Nuclear receptor subfamily 3 group C member 2. (987 aa)
INSRRTyrosine-protein kinase receptor. (1300 aa)
RAMP1Receptor activity modifying protein 1. (145 aa)
LOC101081229Pyruvate kinase; Belongs to the pyruvate kinase family. (353 aa)
SP1Sp1 transcription factor. (786 aa)
LPIN2Lipin 2. (936 aa)
MSTNMyostatin. (375 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa)
GLP2RGlucagon like peptide 2 receptor. (373 aa)
DENND4CDENN domain containing 4C. (1957 aa)
JAK1Tyrosine-protein kinase. (1157 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
EPRS1Glutamyl-prolyl-tRNA synthetase. (1576 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
POU4F2POU domain protein. (408 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (585 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (979 aa)
DNAI1Dynein axonemal intermediate chain 1. (719 aa)
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (246 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (427 aa)
CST11Cystatin 11. (138 aa)
DAXXDeath domain associated protein. (748 aa)
TRIM24Tripartite motif containing 24. (1268 aa)
SSTR5Somatostatin receptor 5; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2240 aa)
TTC6TPR_REGION domain-containing protein. (1880 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
SSTR2Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (979 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (454 aa)
LOC111556172Uncharacterized protein. (536 aa)
ARAndrogen receptor. (903 aa)
JAK3Tyrosine-protein kinase. (1232 aa)
SLC5A5Solute carrier family 5 member 5; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (402 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1323 aa)
ACACBAcetyl-CoA carboxylase beta. (2447 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (720 aa)
UCP1Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
RAMP2Receptor activity modifying protein 2. (206 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa)
NPAS4Neuronal PAS domain protein 4. (800 aa)
TYK2Tyrosine-protein kinase. (1181 aa)
SSTR1Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
PHIPPleckstrin homology domain interacting protein. (1821 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
PADI2Peptidyl arginine deiminase 2. (665 aa)
RARBRetinoic acid receptor beta. (448 aa)
FBXO32F-box protein 32. (355 aa)
KDM3ALysine demethylase 3A. (1324 aa)
CSRP3Cysteine and glycine rich protein 3. (271 aa)
RXRGRetinoid X receptor gamma. (463 aa)
GATA1GATA binding protein 1. (413 aa)
SLIT3Slit guidance ligand 3. (1530 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (873 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2798 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1066 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
GRB10Growth factor receptor bound protein 10. (594 aa)
AUNIPProgestin and adipoQ receptor family member 7. (739 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1657 aa)
TFPITissue factor pathway inhibitor. (331 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (283 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa)
EBI3Epstein-Barr virus induced 3. (226 aa)
STAT6Signal transducer and activator of transcription. (844 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa)
NCOA3Nuclear receptor coactivator. (1412 aa)
SLC30A10Solute carrier family 30 member 10. (483 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1104 aa)
OTOP1Otopetrin 1. (607 aa)
GCGRGlucagon receptor; Belongs to the G-protein coupled receptor 2 family. (484 aa)
TBC1D4TBC1 domain family member 4. (1297 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1208 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (598 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (393 aa)
IRS4Insulin receptor substrate 4. (1251 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa)
SHC1SHC adaptor protein 1. (566 aa)
SLC39A14Solute carrier family 39 member 14. (491 aa)
PHB2Prohibitin. (299 aa)
LOC101100432Uncharacterized protein. (514 aa)
OSTNOsteocrin. (132 aa)
BRD8Bromodomain containing 8. (1236 aa)
M3X5D6_FELCAUncharacterized protein. (92 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
HNF4GHepatocyte nuclear factor 4 gamma. (462 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
URI1URI1 prefoldin like chaperone. (533 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
GOT1Aspartate aminotransferase. (413 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (1045 aa)
ENSFCAP00000060514Uncharacterized protein. (135 aa)
LATS2Non-specific serine/threonine protein kinase. (1095 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (525 aa)
ABHD2Abhydrolase domain containing 2. (477 aa)
AKT2Non-specific serine/threonine protein kinase. (571 aa)
GRB14Growth factor receptor bound protein 14. (717 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (152 aa)
SLC27A4Solute carrier family 27 member 4. (691 aa)
TNFSF4Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (295 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (572 aa)
ESRRGEstrogen related receptor gamma. (506 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
ARID5AAT-rich interaction domain 5A. (608 aa)
CALCOCO1Calcium binding and coiled-coil domain 1. (683 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
ENSFCAP00000055099Uncharacterized protein. (115 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (263 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (142 aa)
PPARGC1BPPARG coactivator 1 beta. (1006 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (899 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (480 aa)
ANKRD26ANK_REP_REGION domain-containing protein. (266 aa)
RAB31RAB31, member RAS oncogene family. (210 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
NKX3-1NK3 homeobox 1. (231 aa)
TRIP4Thyroid hormone receptor interactor 4. (605 aa)
SLC27A1Solute carrier family 27 member 1. (796 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (498 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
RARRES2Retinoic acid receptor responder 2. (451 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
RARGRetinoic acid receptor gamma. (459 aa)
RAB15Uncharacterized protein. (425 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
RBFOX2RNA binding fox-1 homolog 2. (484 aa)
RAB13Uncharacterized protein. (203 aa)
DAXX-2Daxx domain-containing protein. (769 aa)
LOC101097790Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (959 aa)
ACTN2Actinin alpha 2. (910 aa)
YAP1Yes associated protein 1. (498 aa)
JAK2Tyrosine-protein kinase. (1131 aa)
PGRProgesterone receptor. (932 aa)
RXRARetinoid X receptor alpha. (654 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
MGARPMitochondria localized glutamic acid rich protein. (241 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1281 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (651 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta. (69 aa)
ZNF106Zinc finger protein 106. (1902 aa)
ZFP36ZFP36 ring finger protein. (513 aa)
C2CD5C2 calcium dependent domain containing 5. (1126 aa)
STXBP4Uncharacterized protein. (562 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa)
IRS2Insulin receptor substrate 2. (1335 aa)
PIK3R3Uncharacterized protein. (461 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa)
ENSFCAP00000045932Uncharacterized protein. (123 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
ZFP36L2ZFP36 ring finger protein like 2. (705 aa)
SOSTSclerostin. (212 aa)
ARID1AAT-rich interaction domain 1A. (2284 aa)
UBE2L3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (247 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (634 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
ENSFCAP00000044386Uncharacterized protein. (156 aa)
LOC101085801Uncharacterized protein. (467 aa)
PID1Phosphotyrosine interaction domain containing 1. (252 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
PIK3R2Phosphoinositide-3-kinase regulatory subunit 2. (726 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
WT1WT1 transcription factor. (523 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
WBP2GRAM domain-containing protein. (261 aa)
ESR2Estrogen receptor 2. (574 aa)
PHBProhibitin. (272 aa)
RXFP2Relaxin family peptide receptor 2. (713 aa)
NCOA1Nuclear receptor coactivator. (1492 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
RESTRE1 silencing transcription factor. (1045 aa)
PKMPyruvate kinase PKM; Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP (By similarity). Stimulates POU5F1-mediated transcriptional activation (By similarity). Promotes in a STAT1-dependent manner, the expression of the immune checkpoint protein CD274 in ARNTL/BMAL1-deficient macrophages (By similarity). (531 aa)
XBP1X-box binding protein 1. (383 aa)
RAMP3Receptor activity modifying protein 3. (150 aa)
CRHR1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (426 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (400 aa)
SRCTyrosine-protein kinase. (678 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
TFAP4Transcription factor AP-4. (337 aa)
INHBBInhibin subunit beta B. (407 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (541 aa)
UMODL1Uromodulin like 1. (1281 aa)
LEPRLeptin receptor. (1166 aa)
FOXO1Forkhead box O1. (662 aa)
APCAPC regulator of WNT signaling pathway. (2874 aa)
CRADDUncharacterized protein. (398 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (826 aa)
PAX8Paired box 8. (620 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
LPIN1Lipin 1. (976 aa)
CEP170Centrosomal protein 170. (1588 aa)
RHOQRas homolog family member Q. (214 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
RARARetinoic acid receptor alpha. (462 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa)
ACACAAcetyl-CoA carboxylase alpha. (2385 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (489 aa)
SAFBScaffold attachment factor B. (918 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (725 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (935 aa)
BBS4Bardet-Biedl syndrome 4. (525 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
OCSTAMPOsteoclast stimulatory transmembrane protein. (542 aa)
ASIPAgouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). (182 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
FOXO4Forkhead box O4. (515 aa)
AGRPAgouti related neuropeptide. (132 aa)
NCOA5Nuclear receptor coactivator 5. (544 aa)
IGFBP2Insulin like growth factor binding protein 2. (330 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
INSRTyrosine-protein kinase receptor. (1381 aa)
THRBThyroid hormone receptor beta. (476 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
LPIN3Lipin 3. (1036 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. (770 aa)
SRA1Steroid receptor RNA activator 1. (236 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (729 aa)
SIRT1Sirtuin 1. (745 aa)
PTGFRProstaglandin FP receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PPARDPeroxisome proliferator activated receptor delta. (464 aa)
P2RY6Pyrimidinergic receptor P2Y6. (386 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (624 aa)
ENSFCAP00000026456Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (128 aa)
TRHThyrotropin releasing hormone. (276 aa)
SH2B2SH2B adaptor protein 2. (679 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
PAQR8Progestin and adipoQ receptor family member 8. (402 aa)
PRKAA1Non-specific serine/threonine protein kinase. (573 aa)
RB1RB transcriptional corepressor 1. (930 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (576 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
SFR1SWI5 dependent homologous recombination repair protein 1. (232 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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