11 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NKX2-1	NK2 homeobox 1. (399 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2. (541 aa)
	DHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (396 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	AMH	Anti-Mullerian hormone. (800 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (671 aa)
	NKX2-2	NK2 homeobox 2. (273 aa)
	PDGFRA	Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1. (471 aa)
	TMF1	TATA element modulatory factor 1. (1093 aa)
	SF1	Splicing factor 1. (670 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMH	NR5A1	ENSFCAP00000056694	ENSFCAP00000049244	Anti-Mullerian hormone.	Nuclear receptor subfamily 5 group A member 1.	0.478
NKX2-2	NR0B1	ENSFCAP00000008102	ENSFCAP00000016780	NK2 homeobox 2.	Nuclear receptor subfamily 0 group B member 1.	0.403
NR0B1	NKX2-2	ENSFCAP00000016780	ENSFCAP00000008102	Nuclear receptor subfamily 0 group B member 1.	NK2 homeobox 2.	0.403
NR0B1	NR5A1	ENSFCAP00000016780	ENSFCAP00000049244	Nuclear receptor subfamily 0 group B member 1.	Nuclear receptor subfamily 5 group A member 1.	0.979
NR0B1	NR5A2	ENSFCAP00000016780	ENSFCAP00000040336	Nuclear receptor subfamily 0 group B member 1.	Nuclear receptor subfamily 5 group A member 2.	0.731
NR5A1	AMH	ENSFCAP00000049244	ENSFCAP00000056694	Nuclear receptor subfamily 5 group A member 1.	Anti-Mullerian hormone.	0.478
NR5A1	NR0B1	ENSFCAP00000049244	ENSFCAP00000016780	Nuclear receptor subfamily 5 group A member 1.	Nuclear receptor subfamily 0 group B member 1.	0.979
NR5A2	NR0B1	ENSFCAP00000040336	ENSFCAP00000016780	Nuclear receptor subfamily 5 group A member 2.	Nuclear receptor subfamily 0 group B member 1.	0.731