(22 nodes) Protein kinase A regulatory subunit binding network (Felis catus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKAP5	A-kinase anchoring protein 5. (428 aa)
	AKAP11	A-kinase anchoring protein 11. (1908 aa)
	RYR2	Ryanodine receptor 2. (4967 aa)
	EZR	Ezrin. (639 aa)
	AKAP14	Uncharacterized protein. (132 aa)
	PRRC1	Proline rich coiled-coil 1. (460 aa)
	PRKACA	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
	WASF1	WASP family member 1. (570 aa)
	ACBD3	Acyl-CoA binding domain containing 3. (528 aa)
	AKAP7	A-kinase anchoring protein 7. (418 aa)
	ARFGEF2	ADP ribosylation factor guanine nucleotide exchange factor 2. (1785 aa)
	KCNQ1	Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...] (692 aa)
	ARFGEF1	ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
	SPATC1L	Spermatogenesis and centriole associated 1 like. (343 aa)
	PJA2	Praja ring finger ubiquitin ligase 2. (699 aa)
	WASF3	WASP family member 3. (502 aa)
	WASF2	WASP family member 2. (498 aa)
	AKAP1	A-kinase anchoring protein 1. (974 aa)
	GSKIP	GSK3B interacting protein. (139 aa)
	AKAP8L	A-kinase anchoring protein 8 like; Belongs to the AKAP95 family. (650 aa)
	CC1H2orf88	Chromosome C1 C2orf88 homolog. (95 aa)
	SPATC1	Spermatogenesis and centriole associated 1. (464 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP1	AKAP11	ENSFCAP00000006348	ENSFCAP00000037295	A-kinase anchoring protein 1.	A-kinase anchoring protein 11.	0.451
AKAP1	PRKACA	ENSFCAP00000006348	ENSFCAP00000018754	A-kinase anchoring protein 1.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.803
AKAP11	AKAP1	ENSFCAP00000037295	ENSFCAP00000006348	A-kinase anchoring protein 11.	A-kinase anchoring protein 1.	0.451
AKAP11	AKAP7	ENSFCAP00000037295	ENSFCAP00000060102	A-kinase anchoring protein 11.	A-kinase anchoring protein 7.	0.531
AKAP11	PRKACA	ENSFCAP00000037295	ENSFCAP00000018754	A-kinase anchoring protein 11.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.445
AKAP14	AKAP7	ENSFCAP00000059362	ENSFCAP00000060102	Uncharacterized protein.	A-kinase anchoring protein 7.	0.455
AKAP5	PRKACA	ENSFCAP00000021094	ENSFCAP00000018754	A-kinase anchoring protein 5.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.499
AKAP7	AKAP11	ENSFCAP00000060102	ENSFCAP00000037295	A-kinase anchoring protein 7.	A-kinase anchoring protein 11.	0.531
AKAP7	AKAP14	ENSFCAP00000060102	ENSFCAP00000059362	A-kinase anchoring protein 7.	Uncharacterized protein.	0.455
AKAP7	AKAP8L	ENSFCAP00000060102	ENSFCAP00000030337	A-kinase anchoring protein 7.	A-kinase anchoring protein 8 like; Belongs to the AKAP95 family.	0.414
AKAP7	PRKACA	ENSFCAP00000060102	ENSFCAP00000018754	A-kinase anchoring protein 7.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.564
AKAP8L	AKAP7	ENSFCAP00000030337	ENSFCAP00000060102	A-kinase anchoring protein 8 like; Belongs to the AKAP95 family.	A-kinase anchoring protein 7.	0.414
ARFGEF1	ARFGEF2	ENSFCAP00000014407	ENSFCAP00000001341	ADP ribosylation factor guanine nucleotide exchange factor 1.	ADP ribosylation factor guanine nucleotide exchange factor 2.	0.568
ARFGEF2	ARFGEF1	ENSFCAP00000001341	ENSFCAP00000014407	ADP ribosylation factor guanine nucleotide exchange factor 2.	ADP ribosylation factor guanine nucleotide exchange factor 1.	0.568
EZR	PRKACA	ENSFCAP00000055300	ENSFCAP00000018754	Ezrin.	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.971
KCNQ1	PRKACA	ENSFCAP00000044776	ENSFCAP00000018754	Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...]	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.922
KCNQ1	RYR2	ENSFCAP00000044776	ENSFCAP00000054892	Potassium voltage-gated channel subfamily KQT member 1; Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (By similarity). Associates with KCNE beta subunits that modulates current kinetics (By similarity). Induces a voltage-dependent by rapidly activating and slowly deactivating potassium-selective outward current (By similarity). Promotes also a delayed voltage activated potassium current showing outward rectification characteristic (By similarity). During beta-adrenergic receptor stimulation participates in cardiac r [...]	Ryanodine receptor 2.	0.602
PRKACA	AKAP1	ENSFCAP00000018754	ENSFCAP00000006348	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	A-kinase anchoring protein 1.	0.803
PRKACA	AKAP11	ENSFCAP00000018754	ENSFCAP00000037295	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	A-kinase anchoring protein 11.	0.445
PRKACA	AKAP5	ENSFCAP00000018754	ENSFCAP00000021094	Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.	A-kinase anchoring protein 5.	0.499