63 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DERL1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
	SELENOS	Selenoprotein S. (188 aa)
	SERP2	Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (151 aa)
	CREB3L2	cAMP responsive element binding protein 3 like 2. (536 aa)
	TMBIM6	Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (245 aa)
	HSPA14	Heat shock protein family A (Hsp70) member 14; Belongs to the heat shock protein 70 family. (538 aa)
	DERL2	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	HSPA13	Heat shock protein family A (Hsp70) member 13; Belongs to the heat shock protein 70 family. (509 aa)
	RHBDD2	Rhomboid domain containing 2. (367 aa)
	EIF2S1	Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
	HERPUD1	Homocysteine inducible ER protein with ubiquitin like domain 1. (393 aa)
	HSPD1	Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
	BAG3	BCL2 associated athanogene 3. (565 aa)
	CREB3L1	cAMP responsive element binding protein 3 like 1. (520 aa)
	ATF6B	Activating transcription factor 6 beta. (628 aa)
	OS9	OS9 endoplasmic reticulum lectin. (668 aa)
	CREB3L3	cAMP responsive element binding protein 3 like 3. (448 aa)
	ERLEC1	Endoplasmic reticulum lectin 1. (483 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
	CREB3L4	cAMP responsive element binding protein 3 like 4. (423 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (606 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	QRICH1	Glutamine rich 1. (779 aa)
	CDK5RAP3	CDK5 regulatory subunit associated protein 3. (504 aa)
	VAPB	VAMP associated protein B and C. (243 aa)
	ATF4	Activating transcription factor 4. (352 aa)
	AMFR	Autocrine motility factor receptor. (781 aa)
	ABCB10	ATP binding cassette subfamily B member 10. (736 aa)
	TMTC4	Transmembrane O-mannosyltransferase targeting cadherins 4. (742 aa)
	EIF2AK2	Eukaryotic translation initiation factor 2 alpha kinase 2. (541 aa)
	EP300	E1A binding protein p300. (2425 aa)
	HSPA1L	Heat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
	DAXX	Death domain associated protein. (748 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (427 aa)
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (972 aa)
	DDIT3	DNA damage inducible transcript 3. (167 aa)
	HSPA9	Heat shock protein family A (Hsp70) member 9; Belongs to the heat shock protein 70 family. (679 aa)
	ENSFCAP00000057195	Uncharacterized protein. (34 aa)
	CREB3	cAMP responsive element binding protein 3. (399 aa)
	RHBDD1	Rhomboid domain containing 1. (320 aa)
	DNAJC10	DnaJ heat shock protein family (Hsp40) member C10. (785 aa)
	SERP1	Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (76 aa)
	HERPUD2	HERPUD family member 2. (406 aa)
	DAXX-2	Daxx domain-containing protein. (769 aa)
	ATF6	Activating transcription factor 6. (669 aa)
	WFS1	Wolframin ER transmembrane glycoprotein. (888 aa)
	PACRGL	Parkin coregulated like. (294 aa)
	TBL2	Transducin beta like 2. (442 aa)
	PPP1R15A	Protein phosphatase 1 regulatory subunit 15A. (685 aa)
	DERL3	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (245 aa)
	ENSFCAP00000041941	Uncharacterized protein; Belongs to the heat shock protein 70 family. (620 aa)
	XBP1	X-box binding protein 1. (383 aa)
	ENSFCAP00000040280	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
	PARP16	Poly [ADP-ribose] polymerase. (323 aa)
	ENSFCAP00000039745	Uncharacterized protein. (55 aa)
	HSPA8	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (667 aa)
	ENSFCAP00000033387	Uncharacterized protein. (491 aa)
	HSF1	Heat shock transcription factor 1. (527 aa)
	ERN2	Endoplasmic reticulum to nucleus signaling 2. (927 aa)
	ENSFCAP00000025816	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
	TM7SF3	Transmembrane 7 superfamily member 3. (570 aa)
	ATF3	Activating transcription factor 3. (259 aa)
	HSPB8	Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMFR	DERL1	ENSFCAP00000008034	ENSFCAP00000023495	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.996
AMFR	DERL2	ENSFCAP00000008034	ENSFCAP00000023002	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.943
AMFR	DERL3	ENSFCAP00000008034	ENSFCAP00000042029	Autocrine motility factor receptor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.847
AMFR	ERLEC1	ENSFCAP00000008034	ENSFCAP00000012391	Autocrine motility factor receptor.	Endoplasmic reticulum lectin 1.	0.846
AMFR	ERN1	ENSFCAP00000008034	ENSFCAP00000003236	Autocrine motility factor receptor.	Endoplasmic reticulum to nucleus signaling 1.	0.569
AMFR	ERN2	ENSFCAP00000008034	ENSFCAP00000027867	Autocrine motility factor receptor.	Endoplasmic reticulum to nucleus signaling 2.	0.592
AMFR	HERPUD1	ENSFCAP00000008034	ENSFCAP00000019524	Autocrine motility factor receptor.	Homocysteine inducible ER protein with ubiquitin like domain 1.	0.631
AMFR	HERPUD2	ENSFCAP00000008034	ENSFCAP00000050952	Autocrine motility factor receptor.	HERPUD family member 2.	0.406
AMFR	HSPA5	ENSFCAP00000008034	ENSFCAP00000010964	Autocrine motility factor receptor.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.630
AMFR	OS9	ENSFCAP00000008034	ENSFCAP00000013629	Autocrine motility factor receptor.	OS9 endoplasmic reticulum lectin.	0.927
AMFR	SELENOS	ENSFCAP00000008034	ENSFCAP00000023286	Autocrine motility factor receptor.	Selenoprotein S.	0.601
AMFR	XBP1	ENSFCAP00000008034	ENSFCAP00000041558	Autocrine motility factor receptor.	X-box binding protein 1.	0.419
ATF3	ATF4	ENSFCAP00000025287	ENSFCAP00000008612	Activating transcription factor 3.	Activating transcription factor 4.	0.841
ATF3	ATF6	ENSFCAP00000025287	ENSFCAP00000049040	Activating transcription factor 3.	Activating transcription factor 6.	0.674
ATF3	DDIT3	ENSFCAP00000025287	ENSFCAP00000001926	Activating transcription factor 3.	DNA damage inducible transcript 3.	0.902
ATF3	EIF2S1	ENSFCAP00000025287	ENSFCAP00000019535	Activating transcription factor 3.	Eukaryotic translation initiation factor 2 subunit alpha.	0.506
ATF3	HERPUD1	ENSFCAP00000025287	ENSFCAP00000019524	Activating transcription factor 3.	Homocysteine inducible ER protein with ubiquitin like domain 1.	0.452
ATF3	HSPA5	ENSFCAP00000025287	ENSFCAP00000010964	Activating transcription factor 3.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.528
ATF3	XBP1	ENSFCAP00000025287	ENSFCAP00000041558	Activating transcription factor 3.	X-box binding protein 1.	0.700
ATF4	ATF3	ENSFCAP00000008612	ENSFCAP00000025287	Activating transcription factor 4.	Activating transcription factor 3.	0.841