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NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1323 aa) | ||||
ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa) | ||||
ENSFCAP00000060347 | Uncharacterized protein; Belongs to the calmodulin family. (146 aa) | ||||
INPP5K | Inositol polyphosphate-5-phosphatase K. (525 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase. (571 aa) | ||||
GNB5 | G protein subunit beta 5. (403 aa) | ||||
DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa) | ||||
CALM3 | Calmodulin 3; Belongs to the calmodulin family. (276 aa) | ||||
CLIC2 | Chloride intracellular channel 2. (284 aa) | ||||
NEDD4L | NEDD4 like E3 ubiquitin protein ligase. (1246 aa) | ||||
DRD4 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (595 aa) | ||||
FABP5 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (184 aa) | ||||
REM1 | RRAD and GEM like GTPase 1. (238 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) | ||||
CALM1 | Uncharacterized protein; Belongs to the calmodulin family. (192 aa) | ||||
ACTN2 | Actinin alpha 2. (910 aa) | ||||
ARL6IP5 | PRA1 family protein. (188 aa) | ||||
KCNH2 | Potassium voltage-gated channel subfamily H member 2. (1167 aa) | ||||
SLC30A1 | Solute carrier family 30 member 1. (503 aa) | ||||
MRLN | Uncharacterized protein. (46 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (662 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
PEA15 | DED domain-containing protein. (130 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa) | ||||
REM2 | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa) | ||||
KCNE2 | Potassium voltage-gated channel subfamily E regulatory subunit 2. (182 aa) | ||||
KCNE1 | Potassium voltage-gated channel subfamily E member 1; Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 50 seconds. Assembled with K [...] (132 aa) | ||||
EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (192 aa) | ||||
KCNE3 | Potassium voltage-gated channel subfamily E regulatory subunit 3. (99 aa) | ||||
HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1633 aa) | ||||
OAZ3 | Uncharacterized protein. (234 aa) | ||||
PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) | ||||
SLC43A1 | Solute carrier family 43 member 1. (687 aa) | ||||
HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1577 aa) | ||||
CRBN | Cereblon. (518 aa) | ||||
PID1 | Phosphotyrosine interaction domain containing 1. (252 aa) | ||||
SMIM6 | Small integral membrane protein 6. (60 aa) | ||||
LOC101085272 | Uncharacterized protein. (905 aa) | ||||
SESTD1 | SEC14 and spectrin domain containing 1. (758 aa) | ||||
CB1H4orf3 | Uncharacterized protein. (68 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (238 aa) | ||||
GRP | Uncharacterized protein. (265 aa) | ||||
TLR9 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa) | ||||
SLC43A2 | Solute carrier family 43 member 2. (572 aa) | ||||
KCNE5 | Potassium voltage-gated channel subfamily E regulatory subunit 5. (137 aa) | ||||
SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa) | ||||
KCNE4 | Potassium voltage-gated channel subfamily E regulatory subunit 4. (175 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) | ||||
GOPC | PDZ domain-containing protein. (463 aa) | ||||
HAMP | Hepcidin antimicrobial peptide. (83 aa) | ||||
CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) | ||||
ENSFCAP00000029012 | Uncharacterized protein; Belongs to the calmodulin family. (124 aa) | ||||
LOC101097703 | EF-hand domain-containing protein; Belongs to the calmodulin family. (86 aa) | ||||
CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) | ||||
ANO9 | Anoctamin. (769 aa) | ||||
PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) | ||||
PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (204 aa) | ||||
CASQ2 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa) | ||||
KCNRG | Potassium channel regulator. (273 aa) | ||||
GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa) | ||||
OSTN | Osteocrin. (132 aa) | ||||
OSR1 | Odd-skipped related transcription factor 1. (267 aa) | ||||
SRI | Sorcin. (247 aa) | ||||
RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) | ||||
M3WQU5_FELCA | EF-hand domain-containing protein; Belongs to the calmodulin family. (77 aa) | ||||
STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa) | ||||
CALM2 | Calmodulin 2; Belongs to the calmodulin family. (149 aa) | ||||
GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (311 aa) | ||||
KEL | Kell metallo-endopeptidase. (787 aa) | ||||
CTTNBP2NL | CTTNBP2 N-terminal like. (639 aa) | ||||
OXSR1 | Oxidative stress responsive kinase 1. (527 aa) | ||||
GRB10 | Growth factor receptor bound protein 10. (594 aa) | ||||
THBS1 | Thrombospondin 1. (1170 aa) | ||||
OAZ2 | Uncharacterized protein. (189 aa) | ||||
STK39 | Serine/threonine kinase 39. (543 aa) |