STRINGSTRING
MTOR MTOR WNT1 WNT1 LMBR1L LMBR1L DOCK2 DOCK2 GBA GBA SCRIB SCRIB CRTAM CRTAM CLEC4G CLEC4G IL20RB IL20RB STAT5B STAT5B STAT3 STAT3 IL4 IL4 SOX13 SOX13 KIT KIT CCL21 CCL21 EOMES EOMES IDO1 IDO1 CHD7 CHD7 CD4 CD4 PTPN6 PTPN6 PAX1 PAX1 PREX1 PREX1 IFNB1 IFNB1 VAV1 VAV1 ABL1 ABL1 CDH26 CDH26 TNFAIP8L2 TNFAIP8L2 RIPK3 RIPK3 SASH3 SASH3 IL2RA IL2RA TOX TOX IL21 IL21 SH2D2A SH2D2A BCL6 BCL6 LAG3 LAG3 TSPAN32 TSPAN32 CLEC4D CLEC4D WDFY4 WDFY4 AIRE AIRE FOXN1 FOXN1 LFNG LFNG ITCH ITCH HSH2D HSH2D ITK ITK THEMIS THEMIS ZAP70 ZAP70 TBX21 TBX21 JAML JAML CD3D CD3D GLI3 GLI3 IL23A IL23A B2M B2M NLRC3 NLRC3 RHOH RHOH P2RX7 P2RX7 ZNF683 ZNF683 BRAF BRAF PSMB10 PSMB10 SLA2 SLA2 NCAPH2 NCAPH2 IRF1 IRF1 IL2 IL2 STK11 STK11 MSN MSN MALT1 MALT1 EBI3 EBI3 SYK SYK CD28 CD28 STAT6 STAT6 DLL4 DLL4 EPHB6 EPHB6 CRACR2A CRACR2A WAS WAS PTEN PTEN RIPK2 RIPK2 IL15 IL15 ZBTB7B ZBTB7B LRRC1 LRRC1 PSMB11 PSMB11 RAB44 RAB44 SP3 SP3 ITPKB ITPKB PDP PDP HSPD1 HSPD1 RAB29 RAB29 ZBTB1 ZBTB1 SRF SRF LOC101088440 LOC101088440 IKZF3 IKZF3 ELF4 ELF4 GPR89A GPR89A BCL3 BCL3 TNFSF13B TNFSF13B IL6 IL6 ATF2 ATF2 GPR18 GPR18 IL6R IL6R LIG4 LIG4 ZFP36L1 ZFP36L1 IRF4 IRF4 PPP3CB PPP3CB ENSFCAP00000025816 ENSFCAP00000025816 PRR7 PRR7 RELB RELB TREML2 TREML2 IL12B IL12B CBLB CBLB PELI1 PELI1 JAG2 JAG2 DOCK8 DOCK8 LCP1 LCP1 EGR1 EGR1 FZD7 FZD7 CLEC4A CLEC4A RSAD2 RSAD2 CD83 CD83 ARMC5 ARMC5 HLX HLX NRARP NRARP IL7 IL7 IFNA1 IFNA1 LEP LEP SLAMF6 SLAMF6 SMAD3 SMAD3 AZI2 AZI2 CARD11 CARD11 PTGER4 PTGER4 CTSV CTSV BATF BATF CLEC4E CLEC4E TNFSF8 TNFSF8 IL18R1 IL18R1 FCER1G FCER1G CORO1A CORO1A PATZ1 PATZ1 RABL3 RABL3 CCR7 CCR7 RAG2 RAG2 CCND3 CCND3 NCK1 NCK1 IFNA13 IFNA13 FGL2 FGL2 ENSFCAP00000039745 ENSFCAP00000039745 TCIRG1 TCIRG1 LEPR LEPR FUT7 FUT7 FKBP1B FKBP1B ENSFCAP00000040280 ENSFCAP00000040280 RORA RORA BCL11B BCL11B PRKCQ PRKCQ WNT10B WNT10B TMEM98 TMEM98 TNFSF18 TNFSF18 TSC1 TSC1 PTPN2 PTPN2 FOXP3 FOXP3 GATA3 GATA3 CXADR CXADR ENSFCAP00000044386 ENSFCAP00000044386 NKX2-3 NKX2-3 FADD FADD CYP26B1 CYP26B1 TP53 TP53 ENSFCAP00000045821 ENSFCAP00000045821 ZFP36L2 ZFP36L2 RC3H2 RC3H2 ATG5 ATG5 NCSTN NCSTN RC3H1 RC3H1 CRIP3 CRIP3 CD44 CD44 LEF1 LEF1 DLG2 DLG2 PKNOX1 PKNOX1 RUNX2 RUNX2 IL2RG IL2RG CDK6 CDK6 ENSFCAP00000049833 ENSFCAP00000049833 GPAM GPAM CD48 CD48 LY9 LY9 DLG1 DLG1 TRAF3IP2 TRAF3IP2 HES1 HES1 SOX4 SOX4 RAB27A RAB27A LOC105259618 LOC105259618 NDFIP1 NDFIP1 CTPS1 CTPS1 SEMA4A SEMA4A GPR183 GPR183 NKG7 NKG7 CCR9 CCR9 CD84 CD84 RASGRP1 RASGRP1 PTPRC PTPRC TCF7 TCF7 LOC101094088 LOC101094088 ENTPD7 ENTPD7 ADA ADA HMGB1 HMGB1 STOML2 STOML2 ENSFCAP00000059057 ENSFCAP00000059057 CD8A CD8A CD3E CD3E CD2 CD2 ANXA1 ANXA1 JMJD6 JMJD6 ITGAL ITGAL SLAMF7 SLAMF7 CCL19 CCL19 EFNB1 EFNB1 PTPN22 PTPN22 CCR6 CCR6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1830 aa)
GBAGlucosylceramidase. (536 aa)
SCRIBScribble planar cell polarity protein. (1637 aa)
CRTAMCytotoxic and regulatory T cell molecule. (400 aa)
CLEC4GC-type lectin domain family 4 member G. (317 aa)
IL20RBInterleukin 20 receptor subunit beta. (294 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa)
SOX13SRY-box 13. (619 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (979 aa)
CCL21C-C motif chemokine ligand 21. (134 aa)
EOMESEomesodermin. (713 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (407 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
CD4CD4 molecule. (487 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa)
PAX1Paired box 1. (446 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1647 aa)
IFNB1Interferon beta; Has antiviral, antibacterial and anticancer activities. (186 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
CDH26Cadherin 26. (827 aa)
TNFAIP8L2TNF alpha induced protein 8 like 2. (184 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (509 aa)
SASH3SAM and SH3 domain containing 3. (379 aa)
IL2RAInterleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (275 aa)
TOXThymocyte selection associated high mobility group box. (523 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (161 aa)
SH2D2ASH2 domain containing 2A. (383 aa)
BCL6BCL6 transcription repressor. (745 aa)
LAG3Lymphocyte activating 3. (513 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (289 aa)
CLEC4DC-type lectin domain family 4 member D. (284 aa)
WDFY4WDFY family member 4. (3184 aa)
AIREAutoimmune regulator. (549 aa)
FOXN1Forkhead box N1. (646 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (556 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
HSH2DHematopoietic SH2 domain containing. (383 aa)
ITKTyrosine-protein kinase. (620 aa)
THEMISThymocyte selection associated. (645 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
TBX21T-box transcription factor 21. (535 aa)
JAMLUncharacterized protein. (403 aa)
CD3DCD3d molecule. (170 aa)
GLI3GLI family zinc finger 3. (1578 aa)
IL23AInterleukin 23 subunit alpha. (196 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (118 aa)
NLRC3NLR family CARD domain containing 3. (1060 aa)
RHOHRas homolog family member H. (191 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa)
ZNF683Zinc finger protein 683. (600 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
PSMB10Proteasome subunit beta. (273 aa)
SLA2Src like adaptor 2. (262 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (653 aa)
IRF1Interferon regulatory factor. (322 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa)
MSNMoesin. (577 aa)
MALT1MALT1 paracaspase. (848 aa)
EBI3Epstein-Barr virus induced 3. (226 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
CD28T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. (255 aa)
STAT6Signal transducer and activator of transcription. (844 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
EPHB6EPH receptor B6. (1012 aa)
CRACR2ACalcium release activated channel regulator 2A. (723 aa)
WASWASP actin nucleation promoting factor. (501 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
IL15Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. (162 aa)
ZBTB7BUncharacterized protein. (540 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
PSMB11Proteasome subunit beta. (276 aa)
RAB44RAB44, member RAS oncogene family. (984 aa)
SP3Sp3 transcription factor. (713 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (933 aa)
PDPCathepsin L1; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (332 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa)
RAB29RAB29, member RAS oncogene family. (203 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
SRFSerum response factor. (512 aa)
LOC101088440Uncharacterized protein. (183 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
ELF4E74 like ETS transcription factor 4. (658 aa)
GPR89AUncharacterized protein. (490 aa)
BCL3BCL3 transcription coactivator. (454 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (357 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
GPR18G protein-coupled receptor 18. (331 aa)
IL6RInterleukin 6 receptor. (468 aa)
LIG4DNA ligase. (911 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
IRF4Interferon regulatory factor 4. (451 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
ENSFCAP00000025816Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa)
PRR7Proline rich 7, synaptic. (269 aa)
RELBRELB proto-oncogene, NF-kB subunit. (582 aa)
TREML2Triggering receptor expressed on myeloid cells like 2. (333 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (359 aa)
CBLBCbl proto-oncogene B. (1182 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1609 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2101 aa)
LCP1Lymphocyte cytosolic protein 1. (657 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
CLEC4AC-type lectin domain family 4 member A. (238 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (363 aa)
CD83CD83 molecule. (391 aa)
ARMC5Armadillo repeat containing 5. (943 aa)
HLXH2.0 like homeobox. (569 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
IL7Interleukin 7. (158 aa)
IFNA1Interferon alpha; Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase; Belongs to the alpha/beta interferon family. (194 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
SLAMF6Ig-like domain-containing protein. (390 aa)
SMAD3Mothers against decapentaplegic homolog. (457 aa)
AZI25-azacytidine induced 2. (393 aa)
CARD11Caspase recruitment domain family member 11. (1163 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (489 aa)
CTSVCathepsin V; Belongs to the peptidase C1 family. (333 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
CLEC4EC-type lectin domain family 4 member E. (228 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (234 aa)
IL18R1Interleukin 18 receptor 1. (539 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (655 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (687 aa)
RABL3RAB, member of RAS oncogene family like 3. (264 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
RAG2Recombination activating 2. (527 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
NCK1Cytoplasmic protein. (455 aa)
IFNA13Uncharacterized protein. (193 aa)
FGL2Fibrinogen like 2. (440 aa)
ENSFCAP00000039745Uncharacterized protein. (55 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (954 aa)
LEPRLeptin receptor. (1166 aa)
FUT7Fucosyltransferase 7. (340 aa)
FKBP1BPeptidylprolyl isomerase. (238 aa)
ENSFCAP00000040280Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa)
RORARAR related orphan receptor A. (523 aa)
BCL11BUncharacterized protein. (895 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (715 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
TMEM98Transmembrane protein 98. (226 aa)
TNFSF18TNF superfamily member 18. (178 aa)
TSC1TSC complex subunit 1. (1110 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
FOXP3Forkhead box P3. (501 aa)
GATA3GATA binding protein 3. (444 aa)
CXADRUncharacterized protein. (352 aa)
ENSFCAP00000044386Uncharacterized protein. (156 aa)
NKX2-3NK2 homeobox 3. (368 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
ENSFCAP00000045821Uncharacterized protein. (491 aa)
ZFP36L2ZFP36 ring finger protein like 2. (705 aa)
RC3H2Ring finger and CCCH-type domains 2. (1132 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
NCSTNNicastrin. (709 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
CRIP3Cysteine rich protein 3. (212 aa)
CD44CD44 molecule (Indian blood group). (741 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
DLG2Discs large MAGUK scaffold protein 2. (1012 aa)
PKNOX1Homeobox domain-containing protein. (436 aa)
RUNX2RUNX family transcription factor 2. (584 aa)
IL2RGFibronectin type-III domain-containing protein. (390 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (338 aa)
ENSFCAP00000049833AIG1-type G domain-containing protein. (296 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (796 aa)
CD48Ig-like domain-containing protein. (271 aa)
LY9Lymphocyte antigen 9. (618 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
TRAF3IP2TRAF3 interacting protein 2. (567 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
SOX4Transcription factor SOX. (459 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
LOC105259618Ig-like domain-containing protein. (404 aa)
NDFIP1Nedd4 family interacting protein 1. (224 aa)
CTPS1CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (643 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (806 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (362 aa)
NKG7Natural killer cell granule protein 7. (189 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (367 aa)
CD84CD84 molecule. (369 aa)
RASGRP1RAS guanyl releasing protein 1. (877 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
TCF7Transcription factor 7. (556 aa)
LOC101094088AIG1-type G domain-containing protein. (379 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (641 aa)
ADAAdenosine deaminase. (431 aa)
HMGB1Uncharacterized protein. (233 aa)
STOML2Stomatin like 2. (425 aa)
ENSFCAP00000059057AIG1-type G domain-containing protein. (278 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] (248 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] (255 aa)
CD2CD2 molecule. (376 aa)
ANXA1Annexin. (407 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (546 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1290 aa)
SLAMF7SLAM family member 7. (337 aa)
CCL19C-C motif chemokine. (115 aa)
EFNB1Ephrin B1. (427 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (801 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (592 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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