STRINGSTRING
APC APC NCK1 NCK1 TTC36 TTC36 GGNBP2 GGNBP2 SPRED2 SPRED2 ROCK1 ROCK1 COX11 COX11 ENSFCAP00000036821 ENSFCAP00000036821 PRKDC PRKDC PDPK1 PDPK1 NUP62CL NUP62CL CRKL CRKL MICAL1 MICAL1 KIRREL2 KIRREL2 AJUBA AJUBA NTF3 NTF3 PAX6 PAX6 EPHA1 EPHA1 RASIP1 RASIP1 DVL1 DVL1 SPRY2 SPRY2 ZC3H12A ZC3H12A TRIB3 TRIB3 WWTR1 WWTR1 ENSFCAP00000036500 ENSFCAP00000036500 HDAC4 HDAC4 RUBCN RUBCN HMGCR HMGCR SFRP1 SFRP1 GSKIP GSKIP PTPRB PTPRB HGF HGF PPP4R2 PPP4R2 DUSP16 DUSP16 NCOR1 NCOR1 PRKAR2B PRKAR2B CASP3 CASP3 PIP4K2A PIP4K2A SMYD3 SMYD3 ENSFCAP00000031558 ENSFCAP00000031558 ADIPOQ ADIPOQ MACROH2A1 MACROH2A1 PPP4C PPP4C PBK PBK NTRK3 NTRK3 NLRP12 NLRP12 HEG1 HEG1 DUSP10 DUSP10 CDK5RAP1 CDK5RAP1 PTEN PTEN MSTN MSTN DNAJC3 DNAJC3 ATG14 ATG14 FABP4 FABP4 CBL CBL HHEX HHEX PPP1R15B PPP1R15B DDIT4 DDIT4 HSPB1 HSPB1 M3WY96_FELCA M3WY96_FELCA MYADM MYADM PARK7 PARK7 SOCS3 SOCS3 TESK1 TESK1 EMILIN1 EMILIN1 M3X052_FELCA M3X052_FELCA CDKN2D CDKN2D BDKRB2 BDKRB2 ITGB1BP1 ITGB1BP1 PRKAG2 PRKAG2 VPS25 VPS25 RABGEF1 RABGEF1 BMP2 BMP2 CAV3 CAV3 PRNP PRNP GIT1 GIT1 AKT1S1 AKT1S1 ENSFCAP00000030321 ENSFCAP00000030321 SOCS4 SOCS4 QARS1 QARS1 FAM72A FAM72A PKN1 PKN1 CAV1 CAV1 PKIA PKIA DEFB114 DEFB114 CDKN2C CDKN2C TARDBP TARDBP DAB2IP DAB2IP ENSFCAP00000028212 ENSFCAP00000028212 STAP1 STAP1 SIRT1 SIRT1 SRCIN1 SRCIN1 TERF2IP TERF2IP CDKN1A CDKN1A PWP1 PWP1 JUN JUN SMPD1 SMPD1 CACTIN CACTIN TRIM27 TRIM27 LYN LYN LOC101082108 LOC101082108 LATS1 LATS1 CBLB CBLB CBLC CBLC AGT AGT FAM102B FAM102B IBTK IBTK IFNG IFNG NCAPG2 NCAPG2 DUSP7 DUSP7 PARD6A PARD6A FBP1 FBP1 CDK5RAP3 CDK5RAP3 FBXO7 FBXO7 WARS1 WARS1 CORO1C CORO1C DEPTOR DEPTOR DTNBP1 DTNBP1 GRB10 GRB10 NPRL2 NPRL2 NCK2 NCK2 STAT3 STAT3 CTDSPL CTDSPL CTDSP1 CTDSP1 RTRAF RTRAF MAS1 MAS1 NUPR1 NUPR1 SMAD6 SMAD6 SPRED1 SPRED1 DGKQ DGKQ PLK1 PLK1 GADD45B GADD45B SORL1 SORL1 SPRY1 SPRY1 ENSFCAP00000061110 ENSFCAP00000061110 WNK4 WNK4 IRAK3 IRAK3 ENPP1 ENPP1 PIP4K2C PIP4K2C LATS2 LATS2 ENSFCAP00000060155 ENSFCAP00000060155 PLPP3 PLPP3 INPP5K INPP5K SH3BP5 SH3BP5 PIBF1 PIBF1 BAK1 BAK1 PRDX3 PRDX3 ANKLE2 ANKLE2 TNFAIP3 TNFAIP3 ADAR ADAR CEP85 CEP85 PPIA PPIA PTPRC PTPRC SIRT2 SIRT2 RASSF2 RASSF2 ENSFCAP00000056238 ENSFCAP00000056238 ZFYVE28 ZFYVE28 NF1 NF1 ENSFCAP00000055090 ENSFCAP00000055090 PRKCZ PRKCZ ZBED3 ZBED3 BMP4 BMP4 LAX1 LAX1 PYCARD PYCARD SIRT6 SIRT6 FBLN1 FBLN1 TIGAR TIGAR FAM43B FAM43B MYOCD MYOCD PRKAR1A PRKAR1A SOCS1 SOCS1 MIDN MIDN DMTN DMTN IGFBP3 IGFBP3 SHB SHB NOG NOG PIP4K2B PIP4K2B SH3BP5L SH3BP5L PRKAR2A PRKAR2A TMEM130 TMEM130 PPP1R15A PPP1R15A DBNDD1 DBNDD1 CDKN1B CDKN1B PPM1E PPM1E PTPRQ PTPRQ CDKN1C CDKN1C PID1 PID1 ACTN3 ACTN3 PTPN2 PTPN2 INPP5F INPP5F THY1 THY1 PRKN PRKN SAMSN1 SAMSN1 PKIG PKIG SMAD7 SMAD7 FLCN FLCN PTPRO PTPRO PMEPA1 PMEPA1 HNRNPU HNRNPU LOC102902092 LOC102902092 ENSFCAP00000054337 ENSFCAP00000054337 CAMK2N1 CAMK2N1 ENSFCAP00000054025 ENSFCAP00000054025 LOC101101103 LOC101101103 CBFA2T3 CBFA2T3 RGS14 RGS14 CHMP6 CHMP6 TRAF3IP1 TRAF3IP1 FGFR1OP FGFR1OP INCA1 INCA1 LOC111559734 LOC111559734 KLHL31 KLHL31 TSG101 TSG101 RACK1 RACK1 SLC4A1 SLC4A1 SH2B3 SH2B3 SPRY4 SPRY4 PTPN1 PTPN1 SEMA4D SEMA4D NF2 NF2 PTPN6 PTPN6 ERRFI1 ERRFI1 KAT2B KAT2B IMPACT IMPACT LRP5 LRP5 SH3GL2 SH3GL2 PTPRJ PTPRJ TRIB1 TRIB1 MLXIPL MLXIPL ABL1 ABL1 TGFB1 TGFB1 HEXIM1 HEXIM1 LRP6 LRP6 UBASH3B UBASH3B SMCR8 SMCR8 RB1 RB1 SPRY3 SPRY3 CD109 CD109 SOCS5 SOCS5 GBA GBA ZGPAT ZGPAT INPP5J INPP5J PIK3IP1 PIK3IP1 ENG ENG PIP5KL1 PIP5KL1 DUSP6 DUSP6 M3XB87_FELCA M3XB87_FELCA CIB1 CIB1 MVP MVP CTDSP2 CTDSP2 HEXIM2 HEXIM2 PRKAR1B PRKAR1B PRR5L PRR5L LDLRAD4 LDLRAD4 PAQR3 PAQR3 FAM102A FAM102A LRRK2 LRRK2 CD4H9orf72 CD4H9orf72 M3X892_FELCA M3X892_FELCA DBNDD2 DBNDD2 LOC101088701 LOC101088701 TFAP4 TFAP4 SLIT2 SLIT2 ENSFCAP00000040164 ENSFCAP00000040164 GADD45A GADD45A SFRP2 SFRP2 LRRK1 LRRK1 NIBAN1 NIBAN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APCAPC regulator of WNT signaling pathway. (2874 aa)
NCK1Cytoplasmic protein. (455 aa)
TTC36Tetratricopeptide repeat domain 36. (189 aa)
GGNBP2Gametogenetin binding protein 2. (740 aa)
SPRED2Sprouty related EVH1 domain containing 2. (427 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1355 aa)
COX11Cytochrome c oxidase copper chaperone COX11. (275 aa)
ENSFCAP00000036821TDP43_N domain-containing protein. (82 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4108 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
NUP62CLNsp1_C domain-containing protein. (215 aa)
CRKLCRK like proto-oncogene, adaptor protein. (342 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (995 aa)
KIRREL2Kirre like nephrin family adhesion molecule 2. (861 aa)
AJUBAAjuba LIM protein. (548 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
PAX6Paired box 6. (437 aa)
EPHA1EPH receptor A1. (976 aa)
RASIP1Ras interacting protein 1. (943 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (582 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
ENSFCAP00000036500Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (148 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa)
RUBCNRubicon autophagy regulator. (1014 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
GSKIPGSK3B interacting protein. (139 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2215 aa)
HGFHepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). (728 aa)
PPP4R2Protein phosphatase 4 regulatory subunit 2. (415 aa)
DUSP16Dual specificity phosphatase 16. (663 aa)
NCOR1Nuclear receptor corepressor 1. (2515 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (618 aa)
CASP3Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (421 aa)
SMYD3SET and MYND domain containing 3. (428 aa)
ENSFCAP00000031558Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (163 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (283 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
PPP4CSerine/threonine-protein phosphatase. (307 aa)
PBKPDZ binding kinase. (337 aa)
NTRK3Tyrosine-protein kinase receptor. (863 aa)
NLRP12NLR family pyrin domain containing 12. (1034 aa)
HEG1Heart development protein with EGF like domains 1. (1374 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (477 aa)
CDK5RAP1CDK5 regulatory subunit associated protein 1. (583 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
MSTNMyostatin. (375 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
ATG14Autophagy related 14. (510 aa)
FABP4Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
CBLCbl proto-oncogene. (902 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (713 aa)
DDIT4DNA damage inducible transcript 4. (231 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
M3WY96_FELCAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
TESK1Testis associated actin remodelling kinase 1. (628 aa)
EMILIN1Elastin microfibril interfacer 1. (1025 aa)
M3X052_FELCAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa)
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (392 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (213 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
RABGEF1Uncharacterized protein. (491 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (260 aa)
GIT1GIT ArfGAP 1. (770 aa)
AKT1S1AKT1 substrate 1. (276 aa)
ENSFCAP00000030321Uncharacterized protein. (79 aa)
SOCS4Suppressor of cytokine signaling 4. (441 aa)
QARS1Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa)
FAM72AUncharacterized protein. (149 aa)
PKN1Protein kinase N1. (1064 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
PKIAcAMP-dependent protein kinase inhibitor alpha. (120 aa)
DEFB114Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (68 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
TARDBPTAR DNA binding protein. (414 aa)
DAB2IPDAB2 interacting protein. (1166 aa)
ENSFCAP00000028212Uncharacterized protein. (83 aa)
STAP1Signal transducing adaptor family member 1. (282 aa)
SIRT1Sirtuin 1. (745 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1219 aa)
TERF2IPTERF2 interacting protein. (406 aa)
CDKN1ACyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa)
PWP1PWP1 homolog, endonuclein. (500 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (619 aa)
CACTINCactin, spliceosome C complex subunit. (754 aa)
TRIM27Tripartite motif containing 27. (513 aa)
LYNTyrosine-protein kinase. (526 aa)
LOC101082108Ig-like domain-containing protein. (386 aa)
LATS1Large tumor suppressor kinase 1. (1127 aa)
CBLBCbl proto-oncogene B. (1182 aa)
CBLCCbl proto-oncogene C. (494 aa)
AGTAngiotensinogen; Belongs to the serpin family. (547 aa)
FAM102BFamily with sequence similarity 102 member B. (360 aa)
IBTKInhibitor of Bruton tyrosine kinase. (1311 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1139 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (504 aa)
FBXO7F-box protein 7. (444 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
DEPTORDEP domain containing MTOR interacting protein. (411 aa)
DTNBP1Dystrobrevin binding protein 1. (336 aa)
GRB10Growth factor receptor bound protein 10. (594 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (380 aa)
NCK2Cytoplasmic protein. (380 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CTDSPLCTD small phosphatase like. (283 aa)
CTDSP1CTD small phosphatase 1. (261 aa)
RTRAFUncharacterized protein. (244 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
SMAD6Mothers against decapentaplegic homolog. (497 aa)
SPRED1Sprouty related EVH1 domain containing 1. (443 aa)
DGKQDiacylglycerol kinase. (942 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (234 aa)
SORL1Sortilin related receptor 1. (2211 aa)
SPRY1Sprouty RTK signaling antagonist 1. (362 aa)
ENSFCAP00000061110TGF_BETA_2 domain-containing protein. (362 aa)
WNK4WNK lysine deficient protein kinase 4. (1322 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (551 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (1027 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (435 aa)
LATS2Non-specific serine/threonine protein kinase. (1095 aa)
ENSFCAP00000060155TDP43_N domain-containing protein. (130 aa)
PLPP3acidPPc domain-containing protein. (324 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (525 aa)
SH3BP5SH3 domain binding protein 5. (451 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (696 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
PRDX3Peroxiredoxin 3. (270 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (1012 aa)
TNFAIP3TNF alpha induced protein 3. (804 aa)
ADARAdenosine deaminase RNA specific. (995 aa)
CEP85Centrosomal protein 85. (882 aa)
PPIAPeptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (200 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1299 aa)
SIRT2Sirtuin 2. (497 aa)
RASSF2Ras association domain family member 2. (375 aa)
ENSFCAP00000056238Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (185 aa)
ZFYVE28Zinc finger FYVE-type containing 28. (961 aa)
NF1Neurofibromin 1. (2856 aa)
ENSFCAP00000055090Uncharacterized protein. (94 aa)
PRKCZProtein kinase C zeta. (649 aa)
ZBED3Zinc finger BED-type containing 3. (236 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
LAX1Lymphocyte transmembrane adaptor 1. (402 aa)
PYCARDPYD and CARD domain containing. (195 aa)
SIRT6Sirtuin 6. (412 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (428 aa)
FAM43BFamily with sequence similarity 43 member B. (475 aa)
MYOCDMyocardin. (962 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (569 aa)
SOCS1Suppressor of cytokine signaling 1. (203 aa)
MIDNMidnolin. (510 aa)
DMTNDematin actin binding protein. (405 aa)
IGFBP3Insulin like growth factor binding protein 3. (299 aa)
SHBSH2 domain-containing protein. (508 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
SH3BP5LSH3 binding domain protein 5 like. (393 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (401 aa)
TMEM130Transmembrane protein 130. (475 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (685 aa)
DBNDD1Dysbindin domain containing 1. (158 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (754 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2332 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (264 aa)
PID1Phosphotyrosine interaction domain containing 1. (252 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (933 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
THY1Thy-1 cell surface antigen. (161 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (441 aa)
PKIGcAMP-dependent protein kinase inhibitor gamma. (123 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
FLCNUncharacterized protein. (579 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1216 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (331 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (899 aa)
LOC102902092NACHT domain-containing protein. (1031 aa)
ENSFCAP00000054337TDP43_N domain-containing protein. (90 aa)
CAMK2N1Calcium/calmodulin dependent protein kinase II inhibitor 1. (608 aa)
ENSFCAP00000054025Uncharacterized protein. (329 aa)
LOC101101103Uncharacterized protein. (1668 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (758 aa)
RGS14Regulator of G protein signaling 14. (607 aa)
CHMP6Charged multivesicular body protein 6. (263 aa)
TRAF3IP1TRAF3 interacting protein 1. (721 aa)
FGFR1OPFGFR1 oncogene partner. (732 aa)
INCA1Inhibitor of CDK, cyclin A1 interacting protein 1. (256 aa)
LOC111559734Bone morphogenetic protein 7. (426 aa)
KLHL31Kelch like family member 31. (664 aa)
TSG101Tumor susceptibility 101. (400 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (424 aa)
SLC4A1Anion exchange protein. (911 aa)
SH2B3SH2B adaptor protein 3. (578 aa)
SPRY4Sprouty RTK signaling antagonist 4. (321 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (427 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (863 aa)
NF2Neurofibromin 2. (596 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (460 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa)
IMPACTImpact RWD domain protein. (331 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1213 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
MLXIPLMLX interacting protein like. (857 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (359 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
SMCR8SMCR8-C9orf72 complex subunit. (938 aa)
RB1RB transcriptional corepressor 1. (930 aa)
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)
CD109CD109 molecule. (1446 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
GBAGlucosylceramidase. (536 aa)
ZGPATUncharacterized protein. (802 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1003 aa)
PIK3IP1Phosphoinositide-3-kinase interacting protein 1. (311 aa)
ENGEndoglin. (654 aa)
PIP5KL1Phosphatidylinositol-4-phosphate 5-kinase like 1. (396 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
M3XB87_FELCAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (160 aa)
CIB1Calcium and integrin binding 1. (191 aa)
MVPMajor vault protein. (892 aa)
CTDSP2CTD small phosphatase 2. (271 aa)
HEXIM2HEXIM P-TEFb complex subunit 2. (292 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (378 aa)
PRR5LProline rich 5 like. (384 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (306 aa)
PAQR3Progestin and adipoQ receptor family member 3. (311 aa)
FAM102AFamily with sequence similarity 102 member A. (384 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CD4H9orf72Chromosome D4 C9orf72 homolog. (481 aa)
M3X892_FELCAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (144 aa)
DBNDD2Dysbindin domain containing 2. (111 aa)
LOC101088701Ig-like domain-containing protein. (370 aa)
TFAP4Transcription factor AP-4. (337 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
ENSFCAP00000040164TDP43_N domain-containing protein. (85 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha; Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). (165 aa)
SFRP2Secreted frizzled related protein 2. (385 aa)
LRRK1Leucine rich repeat kinase 1. (2188 aa)
NIBAN1Niban apoptosis regulator 1. (929 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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