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EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) | ||||
SCARB2 | Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa) | ||||
APP | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa) | ||||
STAT3 | Signal transducer and activator of transcription. (770 aa) | ||||
SLC4A1 | Anion exchange protein. (911 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (825 aa) | ||||
PRXL2C | Peroxiredoxin like 2C. (232 aa) | ||||
MLXIPL | MLX interacting protein like. (857 aa) | ||||
EP300 | E1A binding protein p300. (2425 aa) | ||||
FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa) | ||||
GPD1 | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa) | ||||
NUPR1 | Nuclear protein 1, transcriptional regulator. (82 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa) | ||||
ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) | ||||
DDIT4 | DNA damage inducible transcript 4. (231 aa) | ||||
TREX1 | Three prime repair exonuclease 1. (314 aa) | ||||
HTR2A | 5-hydroxytryptamine receptor 2A. (470 aa) | ||||
OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1381 aa) | ||||
GIT1 | GIT ArfGAP 1. (770 aa) | ||||
PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) | ||||
NCOR1 | Nuclear receptor corepressor 1. (2515 aa) | ||||
ARL2 | ARL2-SNX15 readthrough (NMD candidate); Belongs to the small GTPase superfamily. Arf family. (184 aa) | ||||
HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1083 aa) | ||||
ZBTB7A | Zinc finger and BTB domain containing 7A. (584 aa) | ||||
FLCN | Uncharacterized protein. (579 aa) | ||||
ACTN3 | Actinin alpha 3 (gene/pseudogene). (933 aa) | ||||
SLC2A6 | Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) | ||||
ENSFCAP00000044386 | Uncharacterized protein. (156 aa) | ||||
PPP1R3B | Protein phosphatase 1 regulatory subunit. (304 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa) | ||||
TIGAR | TP53 induced glycolysis regulatory phosphatase. (428 aa) | ||||
SIRT6 | Sirtuin 6. (412 aa) | ||||
CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (758 aa) |