12 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102900614	Uncharacterized protein. (594 aa)
	AKT2	Non-specific serine/threonine protein kinase. (571 aa)
	ENSFCAP00000053190	DUF4371 domain-containing protein. (595 aa)
	ENSFCAP00000044386	Uncharacterized protein. (156 aa)
	PTH	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa)
	IGF1	Insulin like growth factor 1. (195 aa)
	INSR	Tyrosine-protein kinase receptor. (1381 aa)
	EPM2AIP1	EPM2A interacting protein 1. (608 aa)
	GCK	Phosphotransferase. (466 aa)
	DYRK2	Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSFCAP00000004586	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	AKT3	ENSFCAP00000004586	ENSFCAP00000003410	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT1	ENSFCAP00000044386	ENSFCAP00000004586	ENSFCAP00000044386	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.475
AKT2	AKT1	ENSFCAP00000059662	ENSFCAP00000004586	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	AKT3	ENSFCAP00000059662	ENSFCAP00000003410	Non-specific serine/threonine protein kinase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.918
AKT2	ENSFCAP00000044386	ENSFCAP00000059662	ENSFCAP00000044386	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.475
AKT3	AKT1	ENSFCAP00000003410	ENSFCAP00000004586	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.917
AKT3	AKT2	ENSFCAP00000003410	ENSFCAP00000059662	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.918
AKT3	ENSFCAP00000044386	ENSFCAP00000003410	ENSFCAP00000044386	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.475
ENSFCAP00000044386	AKT1	ENSFCAP00000044386	ENSFCAP00000004586	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.475
ENSFCAP00000044386	AKT2	ENSFCAP00000044386	ENSFCAP00000059662	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.475
ENSFCAP00000044386	AKT3	ENSFCAP00000044386	ENSFCAP00000003410	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.475
ENSFCAP00000044386	GCK	ENSFCAP00000044386	ENSFCAP00000013323	Uncharacterized protein.	Phosphotransferase.	0.681
ENSFCAP00000044386	IGF1	ENSFCAP00000044386	ENSFCAP00000042016	Uncharacterized protein.	Insulin like growth factor 1.	0.804
ENSFCAP00000044386	INSR	ENSFCAP00000044386	ENSFCAP00000030603	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.998
ENSFCAP00000044386	PTH	ENSFCAP00000044386	ENSFCAP00000042163	Uncharacterized protein.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).	0.504
GCK	ENSFCAP00000044386	ENSFCAP00000013323	ENSFCAP00000044386	Phosphotransferase.	Uncharacterized protein.	0.681
IGF1	ENSFCAP00000044386	ENSFCAP00000042016	ENSFCAP00000044386	Insulin like growth factor 1.	Uncharacterized protein.	0.804
IGF1	INSR	ENSFCAP00000042016	ENSFCAP00000030603	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.996
IGF1	PTH	ENSFCAP00000042016	ENSFCAP00000042163	Insulin like growth factor 1.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity).	0.553