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| | PSRC1 | Proline and serine rich coiled-coil 1. (407 aa) |
| | LOC102900145 | CLLAC domain-containing protein. (151 aa) |
| | CDC25B | Cell division cycle 25B. (578 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | SPATC1 | Spermatogenesis and centriole associated 1. (464 aa) |
| | WNK4 | WNK lysine deficient protein kinase 4. (1322 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (383 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (638 aa) |
| | NCF1 | Neutrophil cytosolic factor 1. (390 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (904 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (696 aa) |
| | ENSFCAP00000059417 | CLLAC domain-containing protein. (134 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (357 aa) |
| | RNASE4 | Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (189 aa) |
| | ADCYAP1 | Adenylate cyclase activating polypeptide 1. (318 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4299 aa) |
| | CEMIP | Cell migration inducing hyaluronidase 1. (1397 aa) |
| | RELN | Reelin. (3460 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1522 aa) |
| | MTCP1 | Mature T cell proliferation 1. (117 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (200 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) |
| | CAMKK2 | Calcium/calmodulin dependent protein kinase kinase 2. (683 aa) |
| | RASSF2 | Ras association domain family member 2. (375 aa) |
| | ENSFCAP00000056238 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (185 aa) |
| | RGCC | Regulator of cell cycle. (180 aa) |
| | CCNT2 | Cyclin T2; Belongs to the cyclin family. (742 aa) |
| | CAMKK1 | Calcium/calmodulin dependent protein kinase kinase 1. (509 aa) |
| | LOC102901812 | Uncharacterized protein. (283 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (877 aa) |
| | BOLA3 | MOB kinase activator 1A. (218 aa) |
| | DRD4 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (595 aa) |
| | TAL1 | TAL bHLH transcription factor 1, erythroid differentiation factor. (414 aa) |
| | ENSFCAP00000054025 | Uncharacterized protein. (329 aa) |
| | DOK7 | Docking protein 7. (595 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (747 aa) |
| | PDGFD | Platelet derived growth factor D. (380 aa) |
| | SLC27A1 | Solute carrier family 27 member 1. (796 aa) |
| | INCENP | Inner centromere protein. (937 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1021 aa) |
| | VLDLR | Very low density lipoprotein receptor. (1239 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (170 aa) |
| | TTBK1 | Tau tubulin kinase 1. (1314 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (312 aa) |
| | MRNIP | MRN complex interacting protein. (348 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) |
| | MOB1B | MOB kinase activator 1B. (221 aa) |
| | UCN | Urocortin. (126 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (450 aa) |
| | DAXX-2 | Daxx domain-containing protein. (769 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | CCDC88A | Coiled-coil domain containing 88A. (1874 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1012 aa) |
| | ENSFCAP00000048496 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (62 aa) |
| | DBF4B | DBF4-type domain-containing protein. (307 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa) |
| | CCNT1 | CYCLIN domain-containing protein; Belongs to the cyclin family. (184 aa) |
| | MMD | Monocyte to macrophage differentiation associated. (339 aa) |
| | ALKAL2 | Uncharacterized protein. (60 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | CACUL1 | CDK2 associated cullin domain 1; Belongs to the cullin family. (369 aa) |
| | DVL2 | Dishevelled segment polarity protein 2. (735 aa) |
| | GRM5 | Glutamate metabotropic receptor 5. (1208 aa) |
| | CENPE | Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2700 aa) |
| | RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1700 aa) |
| | TOM1L1 | Target of myb1 like 1 membrane trafficking protein. (521 aa) |
| | ENSFCAP00000044594 | Uncharacterized protein. (62 aa) |
| | ENSFCAP00000044386 | Uncharacterized protein. (156 aa) |
| | STOX1 | Storkhead box 1. (878 aa) |
| | ALKAL1 | Uncharacterized protein. (283 aa) |
| | ALK | Tyrosine-protein kinase receptor. (1279 aa) |
| | CDK5R2 | Cyclin-dependent kinase 5 activator. (370 aa) |
| | ZFP91 | Uncharacterized protein. (574 aa) |
| | RPLP1 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (109 aa) |
| | LCP2 | Lymphocyte cytosolic protein 2. (534 aa) |
| | SASH1 | SAM and SH3 domain containing 1. (1225 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1179 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | MOB3C | MOB kinase activator 3C. (216 aa) |
| | PHB | Prohibitin. (272 aa) |
| | HMGA2 | Uncharacterized protein. (109 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | CCNK | Cyclin K; Belongs to the cyclin family. (582 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | LRP8 | LDL receptor related protein 8. (1015 aa) |
| | TGFA | Transforming growth factor alpha. (192 aa) |
| | MARCKS | Myristoylated alanine rich protein kinase C substrate. (353 aa) |
| | EPGN | Epithelial mitogen. (153 aa) |
| | MOB3B | MOB kinase activator 3B. (318 aa) |
| | PARP16 | Poly [ADP-ribose] polymerase. (323 aa) |
| | DAZAP2 | DAZ associated protein 2. (207 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (872 aa) |
| | ECT2 | Epithelial cell transforming 2. (914 aa) |
| | TLR9 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa) |
| | MOB3A | MOB kinase activator 3A. (217 aa) |
| | GPRC5A | G protein-coupled receptor class C group 5 member A. (363 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | OSBPL8 | Oxysterol-binding protein; Belongs to the OSBP family. (1518 aa) |
| | ENSFCAP00000037196 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (56 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (748 aa) |
| | ENSFCAP00000036500 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (148 aa) |
| | ALS2 | Alsin Rho guanine nucleotide exchange factor ALS2. (1650 aa) |
| | ENSFCAP00000035024 | Uncharacterized protein. (52 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (866 aa) |
| | IGF2 | Insulin like growth factor 2. (280 aa) |
| | BTC | Betacellulin. (194 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | MAPRE3 | Microtubule associated protein RP/EB family member 3. (281 aa) |
| | ENSFCAP00000031558 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (163 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (213 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | ENSFCAP00000031202 | Uncharacterized protein. (94 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | PRNP | Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (260 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1381 aa) |
| | CHI3L1 | Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (383 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1275 aa) |
| | ENSFCAP00000030418 | KH type-2 domain-containing protein. (147 aa) |
| | ENSFCAP00000030239 | Uncharacterized protein. (145 aa) |
| | GPRC5B | G protein-coupled receptor class C group 5 member B. (387 aa) |
| | DAB2IP | DAB2 interacting protein. (1166 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (282 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (927 aa) |
| | CASS4 | Cas scaffold protein family member 4. (818 aa) |
| | SIRT1 | Sirtuin 1. (745 aa) |
| | FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) |
| | CLSPN | Claspin. (1327 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain containing 2. (656 aa) |
| | SRCIN1 | SRC kinase signaling inhibitor 1. (1219 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (359 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) |
| | STRADB | STE20 related adaptor beta. (415 aa) |
| | CAB39 | Calcium binding protein 39. (373 aa) |
| | NOX4 | NADPH oxidase 4. (578 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1484 aa) |
| | IL34 | Interleukin 34. (331 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | TSACC | TSSK6 activating cochaperone. (165 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) |
| | M3XB87_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (160 aa) |
| | CIB1 | Calcium and integrin binding 1. (191 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (870 aa) |
| | AXIN2 | Axin 2. (841 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa) |
| | FERMT2 | Fermitin family member 2. (706 aa) |
| | PDCD10 | Programmed cell death 10. (212 aa) |
| | IL6R | Interleukin 6 receptor. (468 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | M3X892_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (144 aa) |
| | ANGPT4 | Angiopoietin 4. (499 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (547 aa) |
| | ADRA2C | Adrenoceptor alpha 2C. (476 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | TAOK3 | TAO kinase 3. (914 aa) |
| | LOC101087936 | Uncharacterized protein. (373 aa) |
| | DIPK2A | Divergent protein kinase domain 2A. (430 aa) |
| | DBF4 | DBF4 zinc finger. (676 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (929 aa) |
| | ADRA2B | Adrenoceptor alpha 2B. (444 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | SPDYA | Speedy/RINGO cell cycle regulator family member A. (309 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | KIF14 | Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1575 aa) |
| | M3X052_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa) |
| | M3X004_FELCA | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (120 aa) |
| | ABI1 | Abl interactor 1. (508 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | M3WY96_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa) |
| | DDX3X | DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (662 aa) |
| | PRRC1 | Proline rich coiled-coil 1. (460 aa) |
| | NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (574 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa) |
| | CCN1 | Cellular communication network factor 1. (382 aa) |
| | SYAP1 | Synapse associated protein 1. (358 aa) |
| | EREG | Epiregulin. (169 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (865 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | CCNYL1 | Cyclin Y like 1; Belongs to the cyclin family. (363 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | M3WSW9_FELCA | Uncharacterized protein. (162 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | HTR2B | 5-hydroxytryptamine receptor 2B. (503 aa) |
| | SPDYC | Speedy/RINGO cell cycle regulator family member C. (243 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | TCL1B | T cell leukemia/lymphoma 1B. (130 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (608 aa) |
| | LAT | Linker for activation of T cells. (231 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers wit [...] (245 aa) |
| | FBN1 | Fibrillin 1. (2871 aa) |
| | NTRK3 | Tyrosine-protein kinase receptor. (863 aa) |
| | ERBB3 | ERBB3. (1339 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | SPATC1L | Spermatogenesis and centriole associated 1 like. (343 aa) |
| | LTF | Lactotransferrin; Belongs to the transferrin family. (747 aa) |
| | CAB39L | Calcium binding protein 39 like. (193 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | CAMK1 | Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | GPRC5D | G protein-coupled receptor class C group 5 member D. (376 aa) |
| | MALT1 | MALT1 paracaspase. (848 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa) |
| | TCIM | Transcriptional and immune response regulator. (107 aa) |
| | MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa) |
| | DGKQ | Diacylglycerol kinase. (942 aa) |
| | JTB | Jumping translocation breakpoint. (146 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa) |
| | MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa) |
| | MAP3K10 | Mitogen-activated protein kinase kinase kinase. (937 aa) |
| | IL23A | Interleukin 23 subunit alpha. (196 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (502 aa) |
| | RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | GHRL | Appetite-regulating hormone; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (By similarity); Belongs to the motilin family. (117 aa) |
| | MOB2 | MOB kinase activator 2. (277 aa) |
| | FAM20A | FAM20A golgi associated secretory pathway pseudokinase. (537 aa) |
| | SNX9 | Sorting nexin 9. (678 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (724 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa) |
| | TELO2 | Telomere maintenance 2. (824 aa) |
| | M3WDH2_FELCA | Uncharacterized protein. (157 aa) |
| | BORA | BORA aurora kinase A activator. (591 aa) |
| | C1QTNF9 | Adiponectin F1. (332 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1366 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | ADRB2 | Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa) |
| | DVL3 | Dishevelled segment polarity protein 3. (718 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | GAS6 | Growth arrest specific 6. (674 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa) |
| | EPO | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (192 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (835 aa) |
| | CARD10 | Caspase recruitment domain family member 10. (987 aa) |
| | AJUBA | Ajuba LIM protein. (548 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (509 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | ACSL1 | Acyl-CoA synthetase long chain family member 1. (698 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (492 aa) |
| | CD4 | CD4 molecule. (487 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (544 aa) |
| | TRAF4 | TNF receptor-associated factor. (470 aa) |
| | DAXX | Death domain associated protein. (748 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (427 aa) |
| | CSF1R | Macrophage colony-stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulat [...] (1213 aa) |
| | LOC102899310 | Ig-like domain-containing protein. (320 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (972 aa) |
| | STRADA | STE20 related adaptor alpha. (431 aa) |
| | CCL21 | C-C motif chemokine ligand 21. (134 aa) |
| | NEK10 | NIMA related kinase 10. (1173 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (979 aa) |
| | CARTPT | CART prepropeptide. (116 aa) |
| | MAS1 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (558 aa) |
| | LOC101099765 | Uncharacterized protein. (226 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2527 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (305 aa) |
| | AFAP1L2 | Actin filament associated protein 1 like 2. (810 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (749 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (523 aa) |
| | AREG | Amphiregulin. (323 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1599 aa) |
| | TNFSF15 | TNF superfamily member 15. (255 aa) |
