STRINGSTRING
RNFT2 RNFT2 GBA GBA WDR20 WDR20 PSMC2 PSMC2 FBXW7 FBXW7 BAX BAX SOCS5 SOCS5 TNFSF15 TNFSF15 RCN3 RCN3 SOCS4 SOCS4 OGT OGT ENSFCAP00000030321 ENSFCAP00000030321 ENSFCAP00000030418 ENSFCAP00000030418 HPN HPN SOX7 SOX7 ENSFCAP00000031202 ENSFCAP00000031202 CARD9 CARD9 CASP2 CASP2 FBXW9 FBXW9 CDC20 CDC20 FASLG FASLG DIABLO DIABLO TANK TANK RCHY1 RCHY1 SPON1 SPON1 DET1 DET1 SMAD3 SMAD3 PDCD2 PDCD2 RNF14 RNF14 TNP1 TNP1 PSMC1 PSMC1 LOC101098213 LOC101098213 TRIB3 TRIB3 CASP8AP2 CASP8AP2 LOC101101321 LOC101101321 NOD1 NOD1 ADAM8 ADAM8 TRIB2 TRIB2 FGL2 FGL2 SFRP2 SFRP2 FIS1 FIS1 MAP3K5 MAP3K5 MKRN2 MKRN2 P2RX1 P2RX1 LGMN LGMN EPHA4 EPHA4 DVL1 DVL1 ENSFCAP00000030239 ENSFCAP00000030239 HTRA2 HTRA2 KCNE2 KCNE2 CNTN2 CNTN2 HIP1R HIP1R NLRC4 NLRC4 IL1B IL1B ZER1 ZER1 RNFT1 RNFT1 PSME1 PSME1 DAPK1 DAPK1 CLDN4 CLDN4 CASP10 CASP10 TRIB1 TRIB1 AGER AGER BAG6 BAG6 HSPA1L HSPA1L CCDC22 CCDC22 NUB1 NUB1 TMEM259 TMEM259 HSPBP1 HSPBP1 PCOLCE2 PCOLCE2 RNF139 RNF139 FAM162A FAM162A ENSFCAP00000059958 ENSFCAP00000059958 MUL1 MUL1 MAGEF1 MAGEF1 BAK1 BAK1 EFNA1 EFNA1 PSMC6 PSMC6 CLEC7A CLEC7A F12 F12 UACA UACA CTSH CTSH HMGB1 HMGB1 SNX33 SNX33 ARIH2 ARIH2 GRN GRN FOXL2 FOXL2 BOK BOK ASTL ASTL DAP DAP GRAMD4 GRAMD4 ZYG11B ZYG11B NOP53 NOP53 TNIP3 TNIP3 GPLD1 GPLD1 RNF144A RNF144A SIRT2 SIRT2 MTCH1 MTCH1 BID BID RHBDD1 RHBDD1 OSBPL7 OSBPL7 ENSFCAP00000055271 ENSFCAP00000055271 CASP8 CASP8 PIDD1 PIDD1 PIAS1 PIAS1 FBXW8 FBXW8 AGBL4 AGBL4 PCOLCE PCOLCE NKD2 NKD2 SH3D19 SH3D19 RNF217 RNF217 GSN GSN CBFA2T3 CBFA2T3 ENSFCAP00000053469 ENSFCAP00000053469 NKX3-1 NKX3-1 CYFIP2 CYFIP2 APH1B APH1B LPCAT3 LPCAT3 USP5 USP5 BCAP31 BCAP31 MELTF MELTF TNFRSF1B TNFRSF1B NEK5 NEK5 TNP2 TNP2 RNF19B RNF19B PSMC5 PSMC5 F2R F2R S100A9 S100A9 PML PML RACK1 RACK1 TREM2 TREM2 ACER2 ACER2 TFAP4 TFAP4 PDCD6 PDCD6 BTRC BTRC SRC SRC ENSFCAP00000041674 ENSFCAP00000041674 REST REST ENSFCAP00000041941 ENSFCAP00000041941 CDC20B CDC20B SMAD7 SMAD7 PRKN PRKN PLGRKT PLGRKT PSMC3 PSMC3 BAG2 BAG2 CFLAR CFLAR GSK3B GSK3B GPER1 GPER1 PSMD14 PSMD14 PDCD5 PDCD5 STAT3 STAT3 ZYG11A ZYG11A DNAJB2 DNAJB2 PSME3 PSME3 TTBK1 TTBK1 TNFSF10 TNFSF10 COP1 COP1 PSME2 PSME2 EFNA3 EFNA3 TNF TNF PYCARD PYCARD BCL10 BCL10 HIP1 HIP1 CCBE1 CCBE1 SIRT6 SIRT6 FBLN1 FBLN1 BCL2L11 BCL2L11 PMAIP1 PMAIP1 FZR1 FZR1 ATP2A3 ATP2A3 DAB2 DAB2 LOC101082405 LOC101082405 PSME4 PSME4 MAPK9 MAPK9 BAD BAD NCSTN NCSTN CLDN3 CLDN3 BBC3 BBC3 AGTPBP1 AGTPBP1 MYC MYC EGLN3 EGLN3 TMEM130 TMEM130 FADD FADD APH1A APH1A TRIM67 TRIM67 SENP1 SENP1 RNF185 RNF185 CSNK1D CSNK1D NGFR NGFR CAPN3 CAPN3 SART3 SART3 FN1 FN1 CLUL1 CLUL1 S100A10 S100A10 SNX9 SNX9 RNF19A RNF19A LRRK2 LRRK2 PRELID1 PRELID1 S100A8 S100A8 NODAL NODAL RNF144B RNF144B ANGPTL8 ANGPTL8 ACVR1C ACVR1C IST1 IST1 SH3RF3 SH3RF3 CAV1 CAV1 DDA1 DDA1 DAB2IP DAB2IP ENSFCAP00000028212 ENSFCAP00000028212 AXIN1 AXIN1 SIRT1 SIRT1 ENSFCAP00000027525 ENSFCAP00000027525 ENSFCAP00000027328 ENSFCAP00000027328 TBC1D10A TBC1D10A RPS3 RPS3 NUPR1 NUPR1 PACSIN3 PACSIN3 F3 F3 TNIP1 TNIP1 PLK1 PLK1 VSIR VSIR FBXO22 FBXO22 MALT1 MALT1 SYK SYK NDUFA13 NDUFA13 CLU CLU PRICKLE1 PRICKLE1 SMURF1 SMURF1 SGTA SGTA FGFR4 FGFR4 ANP32B ANP32B ARIH1 ARIH1 PTEN PTEN RIPK2 RIPK2 TMTC3 TMTC3 ASPH ASPH CAPN9 CAPN9 FAS FAS NRDC NRDC PRR7 PRR7 MDM2 MDM2 AURKAIP1 AURKAIP1 USP13 USP13 LAPTM5 LAPTM5 AXIN2 AXIN2 ANKIB1 ANKIB1 RNF180 RNF180 LOC101100947 LOC101100947 BBS7 BBS7 GSK3A GSK3A LYN LYN WDR48 WDR48 PSMD10 PSMD10 DDRGK1 DDRGK1 NLRP3 NLRP3 M3X1N0_FELCA M3X1N0_FELCA RAD23A RAD23A CLPX CLPX HERPUD1 HERPUD1 DDX3X DDX3X CIDEB CIDEB PTK2B PTK2B CCN1 CCN1 NLRP6 NLRP6 CASP9 CASP9 TRIM32 TRIM32 SH3RF1 SH3RF1 IFT57 IFT57 PSENEN PSENEN CLN6 CLN6 STUB1 STUB1 AIFM1 AIFM1 USP50 USP50 SH3RF2 SH3RF2 ZC3H12A ZC3H12A IFNG IFNG MYH9 MYH9 PSMC4 PSMC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RNFT2Ring finger protein, transmembrane 2. (445 aa)
GBAGlucosylceramidase. (536 aa)
WDR20WD repeat domain 20. (588 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
FBXW7F-box and WD repeat domain containing 7. (749 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
TNFSF15TNF superfamily member 15. (255 aa)
RCN3Reticulocalbin 3. (328 aa)
SOCS4Suppressor of cytokine signaling 4. (441 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
ENSFCAP00000030321Uncharacterized protein. (79 aa)
ENSFCAP00000030418KH type-2 domain-containing protein. (147 aa)
HPNHepsin; Belongs to the peptidase S1 family. (571 aa)
SOX7Uncharacterized protein. (571 aa)
ENSFCAP00000031202Uncharacterized protein. (94 aa)
CARD9Caspase recruitment domain family member 9. (732 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (451 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
CDC20Cell division cycle 20. (499 aa)
FASLGTumor necrosis factor ligand superfamily member 6, membrane form; Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T- cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. [FasL intr [...] (280 aa)
DIABLOUncharacterized protein. (237 aa)
TANKTRAF family member associated NFKB activator. (445 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (264 aa)
SPON1Spondin 1. (807 aa)
DET1DET1 partner of COP1 E3 ubiquitin ligase. (560 aa)
SMAD3Mothers against decapentaplegic homolog. (457 aa)
PDCD2Programmed cell death 2. (344 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
TNP1Transition protein 1. (55 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
LOC101098213Cytochrome c. (105 aa)
TRIB3Tribbles pseudokinase 3. (357 aa)
CASP8AP2Caspase 8 associated protein 2. (1779 aa)
LOC101101321Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (457 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
ADAM8ADAM metallopeptidase domain 8. (872 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
FGL2Fibrinogen like 2. (440 aa)
SFRP2Secreted frizzled related protein 2. (385 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
LGMNLegumain. (433 aa)
EPHA4EPH receptor A4. (986 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
ENSFCAP00000030239Uncharacterized protein. (145 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (182 aa)
CNTN2Contactin 2. (1103 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
NLRC4NLR family CARD domain containing 4. (1022 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
ZER1Zyg-11 related cell cycle regulator. (766 aa)
RNFT1Ring finger protein, transmembrane 1. (435 aa)
PSME1Proteasome activator subunit 1. (249 aa)
DAPK1Death associated protein kinase 1. (1429 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (482 aa)
TRIB1Tribbles pseudokinase 1. (372 aa)
AGERAdvanced glycosylation end-product specific receptor. (492 aa)
BAG6BCL2 associated athanogene 6. (1184 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
CCDC22Coiled-coil domain containing 22. (631 aa)
NUB1Negative regulator of ubiquitin like proteins 1. (639 aa)
TMEM259Transmembrane protein 259. (681 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (374 aa)
PCOLCE2Procollagen C-endopeptidase enhancer 2. (433 aa)
RNF139Ring finger protein 139. (983 aa)
FAM162AFamily with sequence similarity 162 member A. (167 aa)
ENSFCAP00000059958Uncharacterized protein. (162 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (568 aa)
MAGEF1MAGE family member F1. (316 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (357 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (477 aa)
CLEC7AC-type lectin domain containing 7A. (250 aa)
F12Coagulation factor XII. (639 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1454 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (572 aa)
HMGB1Uncharacterized protein. (233 aa)
SNX33Sorting nexin. (577 aa)
ARIH2RBR-type E3 ubiquitin transferase. (501 aa)
GRNGranulin precursor. (596 aa)
FOXL2Forkhead box L2. (357 aa)
BOKBCL2 family apoptosis regulator BOK. (320 aa)
ASTLMetalloendopeptidase. (425 aa)
DAPUncharacterized protein. (165 aa)
GRAMD4GRAM domain containing 4. (743 aa)
ZYG11BZyg-11 family member B, cell cycle regulator. (750 aa)
NOP53NOP53 ribosome biogenesis factor. (485 aa)
TNIP3TNFAIP3 interacting protein 3. (397 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (873 aa)
RNF144ARBR-type E3 ubiquitin transferase. (534 aa)
SIRT2Sirtuin 2. (497 aa)
MTCH1Mitochondrial carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (542 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (205 aa)
RHBDD1Rhomboid domain containing 1. (320 aa)
OSBPL7Oxysterol-binding protein; Belongs to the OSBP family. (956 aa)
ENSFCAP00000055271PID domain-containing protein. (114 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (479 aa)
PIDD1P53-induced death domain protein 1. (940 aa)
PIAS1Protein inhibitor of activated STAT 1. (664 aa)
FBXW8F-box and WD repeat domain containing 8. (701 aa)
AGBL4ATP/GTP binding protein like 4. (503 aa)
PCOLCEProcollagen C-endopeptidase enhancer. (559 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (488 aa)
SH3D19SH3 domain containing 19. (1048 aa)
RNF217Ring finger protein 217. (621 aa)
GSNGelsolin. (815 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (758 aa)
ENSFCAP00000053469PA28_beta domain-containing protein. (192 aa)
NKX3-1NK3 homeobox 1. (231 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1335 aa)
APH1BUncharacterized protein. (516 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (625 aa)
USP5Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (891 aa)
BCAP31B cell receptor associated protein 31. (370 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (744 aa)
TNFRSF1BTNF receptor superfamily member 1B. (463 aa)
NEK5NIMA related kinase 5. (825 aa)
TNP2Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. (119 aa)
RNF19BRBR-type E3 ubiquitin transferase. (734 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
S100A9Protein S100; Belongs to the S-100 family. (135 aa)
PMLPromyelocytic leukemia. (876 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (424 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (258 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
TFAP4Transcription factor AP-4. (337 aa)
PDCD6Programmed cell death 6. (189 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
SRCTyrosine-protein kinase. (678 aa)
ENSFCAP00000041674AAA domain-containing protein; Belongs to the AAA ATPase family. (189 aa)
RESTRE1 silencing transcription factor. (1045 aa)
ENSFCAP00000041941Uncharacterized protein; Belongs to the heat shock protein 70 family. (620 aa)
CDC20BCell division cycle 20B. (520 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
PLGRKTPlasminogen receptor with a C-terminal lysine. (147 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (439 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (508 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PDCD5Programmed cell death 5. (197 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ZYG11AZyg-11 family member A, cell cycle regulator. (756 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (325 aa)
PSME3Uncharacterized protein. (265 aa)
TTBK1Tau tubulin kinase 1. (1314 aa)
TNFSF10TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (347 aa)
COP1COP1 E3 ubiquitin ligase. (728 aa)
PSME2Proteasome activator subunit 2. (253 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (237 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa)
PYCARDPYD and CARD domain containing. (195 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
HIP1Huntingtin interacting protein 1. (1036 aa)
CCBE1Collagen and calcium binding EGF domains 1. (440 aa)
SIRT6Sirtuin 6. (412 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (705 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (999 aa)
DAB2DAB adaptor protein 2. (769 aa)
LOC101082405AAA domain-containing protein. (330 aa)
PSME4Proteasome activator subunit 4. (1865 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
BADBCL2 associated agonist of cell death. (273 aa)
NCSTNNicastrin. (709 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
BBC3Uncharacterized protein. (193 aa)
AGTPBP1ATP/GTP binding protein 1. (1227 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (439 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (239 aa)
TMEM130Transmembrane protein 130. (475 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (330 aa)
TRIM67Tripartite motif containing 67. (783 aa)
SENP1SUMO specific peptidase 1. (745 aa)
RNF185Ring finger protein 185. (192 aa)
CSNK1DCasein kinase 1 delta. (488 aa)
NGFRNerve growth factor receptor. (421 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (982 aa)
FN1Fibronectin 1. (2475 aa)
CLUL1Clusterin; Belongs to the clusterin family. (468 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
SNX9Sorting nexin 9. (678 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
PRELID1PRELI domain containing 1. (219 aa)
S100A8Protein S100; Belongs to the S-100 family. (124 aa)
NODALNodal growth differentiation factor. (348 aa)
RNF144BRBR-type E3 ubiquitin transferase. (341 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
IST1IST1 factor associated with ESCRT-III. (366 aa)
SH3RF3SH3 domain containing ring finger 3. (878 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
DDA1DET1 and DDB1 associated 1. (102 aa)
DAB2IPDAB2 interacting protein. (1166 aa)
ENSFCAP00000028212Uncharacterized protein. (83 aa)
AXIN1Axin 1. (867 aa)
SIRT1Sirtuin 1. (745 aa)
ENSFCAP00000027525Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ENSFCAP00000027328Cytochrome c domain-containing protein; Belongs to the cytochrome c family. (103 aa)
TBC1D10ATBC1 domain family member 10A. (517 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons 3. (424 aa)
F3Coagulation factor III, tissue factor. (379 aa)
TNIP1TNFAIP3 interacting protein 1. (635 aa)
PLK1Serine/threonine-protein kinase PLK. (604 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
FBXO22F-box protein 22. (409 aa)
MALT1MALT1 paracaspase. (848 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (144 aa)
CLUClusterin; Belongs to the clusterin family. (469 aa)
PRICKLE1Prickle planar cell polarity protein 1. (830 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
SGTASmall glutamine rich tetratricopeptide repeat containing alpha. (334 aa)
FGFR4Fibroblast growth factor receptor. (830 aa)
ANP32BAcidic nuclear phosphoprotein 32 family member B. (253 aa)
ARIH1RBR-type E3 ubiquitin transferase. (555 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
TMTC3Transmembrane O-mannosyltransferase targeting cadherins 3. (915 aa)
ASPHAspartate beta-hydroxylase. (692 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (690 aa)
FASUncharacterized protein. (314 aa)
NRDCNardilysin convertase. (1226 aa)
PRR7Proline rich 7, synaptic. (269 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation. Component of the TRIM28/KAP1-MDM2-p53/TP53 [...] (712 aa)
AURKAIP1Aurora kinase A interacting protein 1. (199 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
LAPTM5Lysosomal protein transmembrane 5. (263 aa)
AXIN2Axin 2. (841 aa)
ANKIB1RBR-type E3 ubiquitin transferase. (1091 aa)
RNF180Ring finger protein 180. (580 aa)
LOC101100947Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
GSK3AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa)
LYNTyrosine-protein kinase. (526 aa)
WDR48WD repeat domain 48. (677 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
DDRGK1DDRGK domain containing 1. (340 aa)
NLRP3NLR family pyrin domain containing 3. (1038 aa)
M3X1N0_FELCAUncharacterized protein. (276 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (362 aa)
CLPXCaseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (393 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (662 aa)
CIDEBCell death inducing DFFA like effector b. (221 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
CCN1Cellular communication network factor 1. (382 aa)
NLRP6NLR family pyrin domain containing 6. (878 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (451 aa)
TRIM32Uncharacterized protein. (669 aa)
SH3RF1SH3 domain containing ring finger 1. (889 aa)
IFT57Intraflagellar transport 57. (429 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
CLN6CLN6 transmembrane ER protein. (312 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
AIFM1Apoptosis inducing factor mitochondria associated 1. (613 aa)
USP50Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (372 aa)
SH3RF2SH3 domain containing ring finger 2. (734 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (582 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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