(17 nodes) Deoxyribose phosphate catabolic process network (Felis catus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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	UPB1	Beta-ureidopropionase 1. (384 aa)
	NT5C1A	5'-nucleotidase, cytosolic IA. (348 aa)
	SAMHD1	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (627 aa)
	M3WS38_FELCA	dUTPase domain-containing protein. (141 aa)
	NUDT15	Nudix hydrolase 15. (164 aa)
	DCTPP1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (170 aa)
	DUT	dUTPase domain-containing protein. (225 aa)
	DERA	Deoxyribose-phosphate aldolase. (369 aa)
	NT5M	5',3'-nucleotidase, mitochondrial. (235 aa)
	NUDT16	Nudix hydrolase 16. (195 aa)
	NUDT18	Nudix hydrolase 18; Belongs to the Nudix hydrolase family. (134 aa)
	URAD	OHCU_decarbox domain-containing protein. (174 aa)
	GDA	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (466 aa)
	ADA	Adenosine deaminase. (431 aa)
	ENSFCAP00000036935	dUTPase domain-containing protein. (148 aa)
	DPYD	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1026 aa)
	NT5C	5', 3'-nucleotidase, cytosolic. (205 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	GDA	ENSFCAP00000057865	ENSFCAP00000059391	Adenosine deaminase.	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	0.464
ADA	NT5C	ENSFCAP00000057865	ENSFCAP00000032366	Adenosine deaminase.	5', 3'-nucleotidase, cytosolic.	0.504
DCTPP1	DUT	ENSFCAP00000026671	ENSFCAP00000027664	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	dUTPase domain-containing protein.	0.410
DCTPP1	ENSFCAP00000036935	ENSFCAP00000026671	ENSFCAP00000036935	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	dUTPase domain-containing protein.	0.410
DCTPP1	M3WS38_FELCA	ENSFCAP00000026671	ENSFCAP00000017174	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	dUTPase domain-containing protein.	0.410
DCTPP1	NT5C	ENSFCAP00000026671	ENSFCAP00000032366	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	5', 3'-nucleotidase, cytosolic.	0.922
DCTPP1	NT5C1A	ENSFCAP00000026671	ENSFCAP00000005600	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	5'-nucleotidase, cytosolic IA.	0.914
DCTPP1	NT5M	ENSFCAP00000026671	ENSFCAP00000049088	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	5',3'-nucleotidase, mitochondrial.	0.911
DPYD	NT5C1A	ENSFCAP00000034474	ENSFCAP00000005600	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	5'-nucleotidase, cytosolic IA.	0.408
DPYD	NUDT15	ENSFCAP00000034474	ENSFCAP00000025838	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Nudix hydrolase 15.	0.795
DPYD	UPB1	ENSFCAP00000034474	ENSFCAP00000001401	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Beta-ureidopropionase 1.	0.927
DUT	DCTPP1	ENSFCAP00000027664	ENSFCAP00000026671	dUTPase domain-containing protein.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.410
DUT	NT5C	ENSFCAP00000027664	ENSFCAP00000032366	dUTPase domain-containing protein.	5', 3'-nucleotidase, cytosolic.	0.940
DUT	NT5C1A	ENSFCAP00000027664	ENSFCAP00000005600	dUTPase domain-containing protein.	5'-nucleotidase, cytosolic IA.	0.901
DUT	NT5M	ENSFCAP00000027664	ENSFCAP00000049088	dUTPase domain-containing protein.	5',3'-nucleotidase, mitochondrial.	0.917
ENSFCAP00000036935	DCTPP1	ENSFCAP00000036935	ENSFCAP00000026671	dUTPase domain-containing protein.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.410
ENSFCAP00000036935	NT5C	ENSFCAP00000036935	ENSFCAP00000032366	dUTPase domain-containing protein.	5', 3'-nucleotidase, cytosolic.	0.431
GDA	ADA	ENSFCAP00000059391	ENSFCAP00000057865	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	Adenosine deaminase.	0.464
M3WS38_FELCA	DCTPP1	ENSFCAP00000017174	ENSFCAP00000026671	dUTPase domain-containing protein.	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	0.410
M3WS38_FELCA	NT5C	ENSFCAP00000017174	ENSFCAP00000032366	dUTPase domain-containing protein.	5', 3'-nucleotidase, cytosolic.	0.431