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| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (797 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (336 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) |
| | PTGDS | Prostaglandin-H2 D-isomerase; Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possib [...] (364 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (274 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (664 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (421 aa) |
| | UPB1 | Beta-ureidopropionase 1. (384 aa) |
| | GGT1 | Uncharacterized protein. (568 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (518 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (374 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa) |
| | CARNS1 | Carnosine synthase 1. (967 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (407 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (979 aa) |
| | SLC27A5 | Solute carrier family 27 member 5. (687 aa) |
| | SEPHS1 | Selenophosphate synthetase 1. (422 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (190 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (588 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1214 aa) |
| | PLA2G5 | Phospholipase A(2). (158 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (405 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (740 aa) |
| | ACSBG1 | Acyl-CoA synthetase bubblegum family member 1. (815 aa) |
| | PTGES3 | Prostaglandin E synthase 3. (164 aa) |
| | SRR | Serine racemase. (339 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (445 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | ASL | Uncharacterized protein. (477 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (285 aa) |
| | BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (404 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (935 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa) |
| | ACSM1 | Acyl-CoA synthetase medium chain family member 1. (654 aa) |
| | DECR2 | 2,4-dienoyl-CoA reductase 2. (241 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2447 aa) |
| | PAH | Phenylalanine hydroxylase. (465 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa) |
| | UROS | Uroporphyrinogen III synthase. (283 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | HNF1A | HNF1 homeobox A. (639 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (445 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (620 aa) |
| | DAGLB | Diacylglycerol lipase beta. (692 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (343 aa) |
| | FASN | Fatty acid synthase. (2655 aa) |
| | TMED8 | Transmembrane p24 trafficking protein family member 8. (315 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (383 aa) |
| | CTH | Cystathionine gamma-lyase. (405 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (671 aa) |
| | PYCR1 | F420_oxidored domain-containing protein. (450 aa) |
| | PTGES2 | Prostaglandin E synthase 2. (373 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (745 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1872 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (154 aa) |
| | FADS1 | Fatty acid desaturase 1. (360 aa) |
| | OAT | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | EDN2 | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (178 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | ILVBL | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (648 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (697 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2250 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (699 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (711 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (406 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (579 aa) |
| | LTC4S | Leukotriene C4 synthase. (150 aa) |
| | ABHD3 | Abhydrolase domain containing 3. (411 aa) |
| | M3WQY6_FELCA | Carrier domain-containing protein. (157 aa) |
| | AASDHPPT | Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa) |
| | PSPH | Phosphoserine phosphatase. (276 aa) |
| | LOC101081589 | Beta_elim_lyase domain-containing protein. (395 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | FADS3 | Fatty acid desaturase 3. (544 aa) |
| | LOC101085921 | Cytochrome b5 heme-binding domain-containing protein. (484 aa) |
| | LOC109492144 | Cytochrome b5 heme-binding domain-containing protein. (447 aa) |
| | NAGS | N-acetylglutamate synthase. (531 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (178 aa) |
| | ASNSD1 | Asparagine synthetase domain containing 1. (643 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (977 aa) |
| | ASS1 | Argininosuccinate synthase 1. (412 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | LIPI | Lipase I. (477 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (146 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (759 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | GATM | Glycine amidinotransferase. (423 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | LOC101089901 | Uncharacterized protein. (485 aa) |
| | ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | FADS6 | Fatty acid desaturase 6. (342 aa) |
| | PNPLA8 | Patatin like phospholipase domain containing 8. (781 aa) |
| | THNSL1 | Threonine synthase like 1. (743 aa) |
| | GGT5 | Gamma-glutamyltransferase 5. (570 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | ASAH2 | Neutral ceramidase. (771 aa) |
| | RGN | Regucalcin. (321 aa) |
| | BHMT | Betaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa) |
| | LOC101092602 | FAD-binding PCMH-type domain-containing protein. (440 aa) |
| | MGLL | Monoglyceride lipase. (368 aa) |
| | HOGA1 | 4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (327 aa) |
| | ARMC7 | Armadillo repeat containing 7. (198 aa) |
| | SCD | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (405 aa) |
| | KMO | Kynurenine 3-monooxygenase. (453 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | LOC101086852 | Uncharacterized protein. (303 aa) |
| | MTHFR | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (695 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (607 aa) |
| | TMEM196 | Transmembrane protein 196. (185 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (674 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (381 aa) |
| | ALOX5AP | Arachidonate 5-lipoxygenase activating protein. (161 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | LGSN | Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (574 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (495 aa) |
| | PLP1 | Proteolipid protein 1. (307 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (283 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1026 aa) |
| | GLS | Glutaminase. (672 aa) |
| | NANP | N-acetylneuraminic acid phosphatase. (267 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2385 aa) |
| | SDS | Serine dehydratase. (328 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | AGXT | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). (414 aa) |
| | GAMT | Guanidinoacetate N-methyltransferase. (436 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | ENSFCAP00000037599 | Ldh_1_C domain-containing protein. (60 aa) |
| | QKI | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). (341 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (434 aa) |
| | PTGES | Prostaglandin E synthase. (153 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (373 aa) |
| | LIPH | Lipase H. (451 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (496 aa) |
| | LDHC | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (358 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa) |
| | LDHA | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa) |
| | LOC109492298 | FA_desaturase domain-containing protein. (333 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (344 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (287 aa) |
| | GATD1 | Glutamine amidotransferase like class 1 domain containing 1. (220 aa) |
| | THNSL2 | Threonine synthase like 2. (524 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (167 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | GLUL | Glutamine synthetase. (506 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | PLA2G10 | Phospholipase A(2). (162 aa) |
| | LTA4H | Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (619 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (678 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (269 aa) |
| | LOC101095082 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (347 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (388 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (496 aa) |
| | AKR1A1 | Aldo-keto reductase family 1 member A1. (356 aa) |
| | LIPC | Lipase C, hepatic type. (499 aa) |
| | LOC102900010 | AMP-binding domain-containing protein. (758 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity). (482 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (548 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (469 aa) |
| | SEPHS2 | Selenophosphate synthetase 2. (340 aa) |
| | MRRF | Prostaglandin-endoperoxide synthase 1. (633 aa) |
| | ENSFCAP00000056800 | Uncharacterized protein. (102 aa) |
| | ENSFCAP00000056811 | Uncharacterized protein. (101 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (640 aa) |
| | GAD1 | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. (611 aa) |
| | GSTP1 | Uncharacterized protein; Belongs to the GST superfamily. (438 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (558 aa) |
| | WDR37 | WD repeat domain 37. (616 aa) |
| | TECR | Trans-2,3-enoyl-CoA reductase. (532 aa) |
| | PHGDH | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (586 aa) |
| | CBS | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (633 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (212 aa) |
| | ABHD2 | Abhydrolase domain containing 2. (477 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (542 aa) |
| | ALKBH3 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa) |
| | ENSFCAP00000060223 | Uncharacterized protein; Belongs to the LDH/MDH superfamily. (334 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (305 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (586 aa) |
