STRINGSTRING
GPR20 GPR20 NOTCH1 NOTCH1 LPAR1 LPAR1 ITPKB ITPKB GPR35 GPR35 KRAS KRAS COL3A1 COL3A1 GPR17 GPR17 CSF1 CSF1 NOTCH2 NOTCH2 EPO EPO PIK3CG PIK3CG F2R F2R P2RY8 P2RY8 RASGRP4 RASGRP4 PRAG1 PRAG1 MCF2L MCF2L RASGRP1 RASGRP1 LPAR6 LPAR6 LOC111561928 LOC111561928 F2RL3 F2RL3 ADGRG1 ADGRG1 LRRC7 LRRC7 SHOC2 SHOC2 AUTS2 AUTS2 RASGEF1A RASGEF1A NTRK1 NTRK1 DGKI DGKI F2RL2 F2RL2 F11R F11R LRRD1 LRRD1 NET1 NET1 SYNPO2L SYNPO2L P2RY10 P2RY10 ABRA ABRA AKAP13 AKAP13 MAPRE2 MAPRE2 FGF10 FGF10 ARHGEF3 ARHGEF3 RTN4R RTN4R PIK3CB PIK3CB LRRC59 LRRC59 GPR55 GPR55 GPR18 GPR18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR20G protein-coupled receptor 20; Belongs to the G-protein coupled receptor 1 family. (366 aa)
NOTCH1Notch receptor 1. (2543 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (933 aa)
GPR35G protein-coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (395 aa)
KRASUncharacterized protein. (380 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (339 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa)
NOTCH2Notch receptor 2. (2493 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. (192 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
P2RY8P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (357 aa)
RASGRP4RAS guanyl releasing protein 4. (671 aa)
PRAG1PEAK1 related, kinase-activating pseudokinase 1. (1401 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1196 aa)
RASGRP1RAS guanyl releasing protein 1. (877 aa)
LPAR6G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (344 aa)
LOC111561928G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (479 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (689 aa)
LRRC7Leucine rich repeat containing 7. (1575 aa)
SHOC2SHOC2 leucine rich repeat scaffold protein. (582 aa)
AUTS2Activator of transcription and developmental regulator AUTS2. (1258 aa)
RASGEF1ARasGEF domain family member 1A. (488 aa)
NTRK1Tyrosine-protein kinase receptor. (770 aa)
DGKIDiacylglycerol kinase. (1082 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (378 aa)
F11RJunctional adhesion molecule A; Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation. (Microbial infection) In case of orthoreovirus infection, serves as rec [...] (378 aa)
LRRD1Uncharacterized protein. (229 aa)
NET1Neuroepithelial cell transforming 1. (591 aa)
SYNPO2LSynaptopodin 2 like. (973 aa)
P2RY10P2Y receptor family member 10. (389 aa)
ABRAActin binding Rho activating protein. (372 aa)
AKAP13Uncharacterized protein. (1431 aa)
MAPRE2Microtubule associated protein RP/EB family member 2. (326 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (618 aa)
RTN4RReticulon 4 receptor. (474 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LRRC59Leucine rich repeat containing 59. (306 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
GPR18G protein-coupled receptor 18. (331 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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