STRINGSTRING
ATP7B ATP7B HSF1 HSF1 DAXX-2 DAXX-2 MT4 MT4 NFE2L2 NFE2L2 LOXL2 LOXL2 PARK7 PARK7 AOC1 AOC1 AQP1 AQP1 PRNP PRNP IL1A IL1A LOXL3 LOXL3 DAXX DAXX ENSFCAP00000030926 ENSFCAP00000030926
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP7BATPase copper transporting beta. (1470 aa)
HSF1Heat shock transcription factor 1. (527 aa)
DAXX-2Daxx domain-containing protein. (769 aa)
MT4Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (62 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
LOXL2Lysyl oxidase like 2. (773 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
AOC1Amine oxidase. (757 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...] (260 aa)
IL1AInterleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (270 aa)
LOXL3Lysyl oxidase like 3. (974 aa)
DAXXDeath domain associated protein. (748 aa)
ENSFCAP00000030926Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (57 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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