STRINGSTRING
IL7 IL7 P3H4 P3H4 RAB3D RAB3D LGR4 LGR4 CTHRC1 CTHRC1 TGFB1 TGFB1 TNFSF11 TNFSF11 HTR1B HTR1B ADRB2 ADRB2 HNF1A HNF1A NOTCH2 NOTCH2 EPHA2 EPHA2 NCDN NCDN TGFB3 TGFB3 TPP1 TPP1 PTK2B PTK2B IAPP IAPP TPH1 TPH1 PTN PTN WNT16 WNT16 GPR55 GPR55 LRP5 LRP5 NOX4 NOX4 CCDC154 CCDC154 PTH1R PTH1R MITF MITF TCIRG1 TCIRG1 LOC111559084 LOC111559084 LRRK1 LRRK1 ACP5 ACP5 SRC SRC EXT1 EXT1 EFNA2 EFNA2 TRAF6 TRAF6 LTBP3 LTBP3 SNX10 SNX10 RASSF2 RASSF2 SPP2 SPP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL7Interleukin 7. (158 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (576 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
CTHRC1Collagen triple helix repeat containing 1. (244 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
HTR1B5-hydroxytryptamine receptor 1B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopami [...] (389 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
HNF1AHNF1 homeobox A. (639 aa)
NOTCH2Notch receptor 2. (2493 aa)
EPHA2EPH receptor A2. (936 aa)
NCDNNeurochondrin. (732 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TPP1Tripeptidyl peptidase 1. (562 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
IAPPIslet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family. (89 aa)
TPH1Tryptophan hydroxylase 1. (527 aa)
PTNPleiotrophin. (179 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (475 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa)
NOX4NADPH oxidase 4. (578 aa)
CCDC154Coiled-coil domain containing 154. (524 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (590 aa)
MITFMelanocyte inducing transcription factor. (502 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (954 aa)
LOC111559084Peptidase S53 domain-containing protein. (572 aa)
LRRK1Leucine rich repeat kinase 1. (2188 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
SRCTyrosine-protein kinase. (678 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (263 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1302 aa)
SNX10Sorting nexin 10. (201 aa)
RASSF2Ras association domain family member 2. (375 aa)
SPP2Secreted phosphoprotein 2. (243 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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