19 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GTF2H1	General transcription factor IIH subunit 1. (548 aa)
	GTF2B	General transcription factor IIB. (285 aa)
	MED16	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (828 aa)
	PRMT2	Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (434 aa)
	MED13	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
	MED4	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (270 aa)
	TACC1	Transforming acidic coiled-coil containing protein 1. (801 aa)
	TAF7L	TATA-box binding protein associated factor 7 like. (489 aa)
	MED30	Mediator complex subunit 30. (178 aa)
	BRD8	Bromodomain containing 8. (1236 aa)
	THRAP3	Thyroid hormone receptor associated protein 3. (958 aa)
	MED24	Mediator complex subunit 24. (1023 aa)
	NCOR1	Nuclear receptor corepressor 1. (2515 aa)
	TAF7	TATA-box binding protein associated factor 7. (349 aa)
	MED12	Mediator complex subunit 12. (2278 aa)
	MED17	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (692 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
	NCOA6	Nuclear receptor coactivator 6. (2080 aa)
	ARID5A	AT-rich interaction domain 5A. (608 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRD8	MED1	ENSFCAP00000021826	ENSFCAP00000044432	Bromodomain containing 8.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.435
GTF2B	GTF2H1	ENSFCAP00000005538	ENSFCAP00000006603	General transcription factor IIB.	General transcription factor IIH subunit 1.	0.961
GTF2B	MED1	ENSFCAP00000005538	ENSFCAP00000044432	General transcription factor IIB.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.684
GTF2B	MED16	ENSFCAP00000005538	ENSFCAP00000006777	General transcription factor IIB.	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.612
GTF2B	MED17	ENSFCAP00000005538	ENSFCAP00000041514	General transcription factor IIB.	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.909
GTF2B	MED24	ENSFCAP00000005538	ENSFCAP00000031958	General transcription factor IIB.	Mediator complex subunit 24.	0.660
GTF2B	MED30	ENSFCAP00000005538	ENSFCAP00000020854	General transcription factor IIB.	Mediator complex subunit 30.	0.670
GTF2B	MED4	ENSFCAP00000005538	ENSFCAP00000014207	General transcription factor IIB.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.817
GTF2B	TAF7	ENSFCAP00000005538	ENSFCAP00000040214	General transcription factor IIB.	TATA-box binding protein associated factor 7.	0.883
GTF2B	TAF7L	ENSFCAP00000005538	ENSFCAP00000017771	General transcription factor IIB.	TATA-box binding protein associated factor 7 like.	0.883
GTF2H1	GTF2B	ENSFCAP00000006603	ENSFCAP00000005538	General transcription factor IIH subunit 1.	General transcription factor IIB.	0.961
GTF2H1	MED1	ENSFCAP00000006603	ENSFCAP00000044432	General transcription factor IIH subunit 1.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.525
GTF2H1	MED16	ENSFCAP00000006603	ENSFCAP00000006777	General transcription factor IIH subunit 1.	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.585
GTF2H1	MED17	ENSFCAP00000006603	ENSFCAP00000041514	General transcription factor IIH subunit 1.	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.627
GTF2H1	MED24	ENSFCAP00000006603	ENSFCAP00000031958	General transcription factor IIH subunit 1.	Mediator complex subunit 24.	0.585
GTF2H1	MED30	ENSFCAP00000006603	ENSFCAP00000020854	General transcription factor IIH subunit 1.	Mediator complex subunit 30.	0.585
GTF2H1	MED4	ENSFCAP00000006603	ENSFCAP00000014207	General transcription factor IIH subunit 1.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.734
GTF2H1	TAF7	ENSFCAP00000006603	ENSFCAP00000040214	General transcription factor IIH subunit 1.	TATA-box binding protein associated factor 7.	0.697
GTF2H1	TAF7L	ENSFCAP00000006603	ENSFCAP00000017771	General transcription factor IIH subunit 1.	TATA-box binding protein associated factor 7 like.	0.697
MED1	BRD8	ENSFCAP00000044432	ENSFCAP00000021826	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Bromodomain containing 8.	0.435