STRINGSTRING
CDC73 CDC73 MORC3 MORC3 EMD EMD NUPR1 NUPR1 DACH1 DACH1 TP53INP1 TP53INP1 FBXO4 FBXO4 IFI30 IFI30 B4GALT7 B4GALT7 TRIM32 TRIM32 PAWR PAWR LZTS2 LZTS2 DAB2IP DAB2IP CAV1 CAV1 SFRP1 SFRP1 LOC101088701 LOC101088701 C1QL4 C1QL4 PEX2 PEX2 MYC MYC TP53 TP53 MED31 MED31 INCA1 INCA1 NF1 NF1 MED25 MED25
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC73Cell division cycle 73. (531 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
EMDEmerin. (260 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
DACH1Dachshund family transcription factor 1. (711 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
FBXO4F-box protein 4. (387 aa)
IFI30IFI30 lysosomal thiol reductase. (218 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (381 aa)
TRIM32Uncharacterized protein. (669 aa)
PAWRPro-apoptotic WT1 regulator. (347 aa)
LZTS2Leucine zipper tumor suppressor 2. (645 aa)
DAB2IPDAB2 interacting protein. (1166 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
LOC101088701Ig-like domain-containing protein. (370 aa)
C1QL4Complement C1q like 4. (238 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (439 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
INCA1Inhibitor of CDK, cyclin A1 interacting protein 1. (256 aa)
NF1Neurofibromin 1. (2856 aa)
MED25Mediator complex subunit 25. (795 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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