58 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
	TBXT	T-box transcription factor T. (435 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	NANOG	Nanog homeobox. (311 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
	EOMES	Eomesodermin. (713 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	NF2	Neurofibromin 2. (596 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1066 aa)
	CRB2	Crumbs cell polarity complex component 2. (1283 aa)
	ACCS	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (863 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (261 aa)
	KDM6A	Lysine demethylase 6A. (1453 aa)
	HNF1A	HNF1 homeobox A. (639 aa)
	EPHA2	EPH receptor A2. (936 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1177 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (218 aa)
	TBX19	T-box transcription factor 19. (445 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
	FOXF1	Forkhead box F1. (459 aa)
	KDM6B	Lysine demethylase 6B. (1769 aa)
	LOC101084379	Homeobox domain-containing protein. (290 aa)
	SRF	Serum response factor. (512 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
	TWSG1	Twisted gastrulation BMP signaling modulator 1. (223 aa)
	EXOC4	Exocyst complex component 4. (975 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (378 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	LOC101092829	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (165 aa)
	AXIN1	Axin 1. (867 aa)
	APELA	Uncharacterized protein. (54 aa)
	ARMC5	Armadillo repeat containing 5. (943 aa)
	ITGB1	Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa)
	ITGB4	Integrin beta. (1828 aa)
	SMAD3	Mothers against decapentaplegic homolog. (457 aa)
	SETD2	SET domain containing 2, histone lysine methyltransferase. (2563 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	HOXA11	Homeobox A11. (327 aa)
	TLX2	T cell leukemia homeobox 2. (284 aa)
	SFRP2	Secreted frizzled related protein 2. (385 aa)
	HMGA2	Uncharacterized protein. (109 aa)
	TBX6	T-box transcription factor 6. (436 aa)
	INHBA	Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins (By similarity). (424 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (659 aa)
	LEF1	Lymphoid enhancer binding factor 1. (415 aa)
	TBX3	T-box transcription factor 3. (745 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (569 aa)
	LOC101093046	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (208 aa)
	MSGN1	Mesogenin 1. (193 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	TAL1	TAL bHLH transcription factor 1, erythroid differentiation factor. (414 aa)
	POFUT2	Uncharacterized protein. (725 aa)
	ETV2	ETS variant 2. (249 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	LEF1	ENSFCAP00000027879	ENSFCAP00000048724	Axin 1.	Lymphoid enhancer binding factor 1.	0.960
AXIN1	WNT3	ENSFCAP00000027879	ENSFCAP00000010965	Axin 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.607
AXIN1	WNT3A	ENSFCAP00000027879	ENSFCAP00000035820	Axin 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.607
BMP4	BMPR1A	ENSFCAP00000051185	ENSFCAP00000024415	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.996
BMP4	BMPR2	ENSFCAP00000051185	ENSFCAP00000013072	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.992
BMP4	EOMES	ENSFCAP00000051185	ENSFCAP00000003319	Bone morphogenetic protein 4.	Eomesodermin.	0.514
BMP4	EYA1	ENSFCAP00000051185	ENSFCAP00000000226	Bone morphogenetic protein 4.	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.	0.427
BMP4	FOXF1	ENSFCAP00000051185	ENSFCAP00000017422	Bone morphogenetic protein 4.	Forkhead box F1.	0.481
BMP4	ITGB1	ENSFCAP00000051185	ENSFCAP00000031914	Bone morphogenetic protein 4.	Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...]	0.410
BMP4	LEF1	ENSFCAP00000051185	ENSFCAP00000048724	Bone morphogenetic protein 4.	Lymphoid enhancer binding factor 1.	0.643
BMP4	LOC101084379	ENSFCAP00000051185	ENSFCAP00000018204	Bone morphogenetic protein 4.	Homeobox domain-containing protein.	0.661
BMP4	NANOG	ENSFCAP00000051185	ENSFCAP00000001505	Bone morphogenetic protein 4.	Nanog homeobox.	0.726
BMP4	NOG	ENSFCAP00000051185	ENSFCAP00000046242	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.998
BMP4	SMAD1	ENSFCAP00000051185	ENSFCAP00000003810	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.676
BMP4	SMAD3	ENSFCAP00000051185	ENSFCAP00000034334	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.702
BMP4	TBX19	ENSFCAP00000051185	ENSFCAP00000013957	Bone morphogenetic protein 4.	T-box transcription factor 19.	0.404
BMP4	TBX3	ENSFCAP00000051185	ENSFCAP00000048975	Bone morphogenetic protein 4.	T-box transcription factor 3.	0.478
BMP4	TBX6	ENSFCAP00000051185	ENSFCAP00000044519	Bone morphogenetic protein 4.	T-box transcription factor 6.	0.555
BMP4	TBXT	ENSFCAP00000051185	ENSFCAP00000000720	Bone morphogenetic protein 4.	T-box transcription factor T.	0.404
BMP4	TWSG1	ENSFCAP00000051185	ENSFCAP00000021683	Bone morphogenetic protein 4.	Twisted gastrulation BMP signaling modulator 1.	0.495