18 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRKL	CRK like proto-oncogene, adaptor protein. (342 aa)
	ESRRG	Estrogen related receptor gamma. (506 aa)
	RARG	Retinoic acid receptor gamma. (459 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	RXRA	Retinoid X receptor alpha. (654 aa)
	PTF1A	Pancreas associated transcription factor 1a. (327 aa)
	ENSFCAP00000045932	Uncharacterized protein. (123 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	LOC101085801	Uncharacterized protein. (467 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (549 aa)
	RARA	Retinoic acid receptor alpha. (462 aa)
	ACTN4	Actinin alpha 4. (933 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2. (576 aa)
	RXRG	Retinoid X receptor gamma. (463 aa)
	RARB	Retinoic acid receptor beta. (448 aa)
	LOC111556172	Uncharacterized protein. (536 aa)
	PML	Promyelocytic leukemia. (876 aa)
	SNW1	SNW domain containing 1. (570 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH1A2	CYP26B1	ENSFCAP00000041980	ENSFCAP00000045334	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.942
CYP26B1	ALDH1A2	ENSFCAP00000045334	ENSFCAP00000041980	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.	0.942
CYP26B1	RARB	ENSFCAP00000045334	ENSFCAP00000009659	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Retinoic acid receptor beta.	0.479
CYP26B1	RARG	ENSFCAP00000045334	ENSFCAP00000051056	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	Retinoic acid receptor gamma.	0.410
ENSFCAP00000045932	LOC101085801	ENSFCAP00000045932	ENSFCAP00000043848	Uncharacterized protein.	Uncharacterized protein.	0.777
ENSFCAP00000045932	PPARG	ENSFCAP00000045932	ENSFCAP00000050722	Uncharacterized protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.744
ENSFCAP00000045932	RARA	ENSFCAP00000045932	ENSFCAP00000035501	Uncharacterized protein.	Retinoic acid receptor alpha.	0.579
ENSFCAP00000045932	RARB	ENSFCAP00000045932	ENSFCAP00000009659	Uncharacterized protein.	Retinoic acid receptor beta.	0.855
ENSFCAP00000045932	RARG	ENSFCAP00000045932	ENSFCAP00000051056	Uncharacterized protein.	Retinoic acid receptor gamma.	0.579
ENSFCAP00000045932	RXRG	ENSFCAP00000045932	ENSFCAP00000009995	Uncharacterized protein.	Retinoid X receptor gamma.	0.682
LOC101085801	ENSFCAP00000045932	ENSFCAP00000043848	ENSFCAP00000045932	Uncharacterized protein.	Uncharacterized protein.	0.777
LOC101085801	PPARG	ENSFCAP00000043848	ENSFCAP00000050722	Uncharacterized protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.973
LOC101085801	RARA	ENSFCAP00000043848	ENSFCAP00000035501	Uncharacterized protein.	Retinoic acid receptor alpha.	0.910
LOC101085801	RARB	ENSFCAP00000043848	ENSFCAP00000009659	Uncharacterized protein.	Retinoic acid receptor beta.	0.973
LOC101085801	RARG	ENSFCAP00000043848	ENSFCAP00000051056	Uncharacterized protein.	Retinoic acid receptor gamma.	0.572
LOC101085801	RXRA	ENSFCAP00000043848	ENSFCAP00000049471	Uncharacterized protein.	Retinoid X receptor alpha.	0.934
LOC101085801	RXRG	ENSFCAP00000043848	ENSFCAP00000009995	Uncharacterized protein.	Retinoid X receptor gamma.	0.929
LOC111556172	PPARG	ENSFCAP00000006476	ENSFCAP00000050722	Uncharacterized protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.744
LOC111556172	RARA	ENSFCAP00000006476	ENSFCAP00000035501	Uncharacterized protein.	Retinoic acid receptor alpha.	0.572
LOC111556172	RARB	ENSFCAP00000006476	ENSFCAP00000009659	Uncharacterized protein.	Retinoic acid receptor beta.	0.851