STRINGSTRING
LRP5 LRP5 ETV2 ETV2 SHH SHH JMJD6 JMJD6 ENSFCAP00000060656 ENSFCAP00000060656 ANGPTL6 ANGPTL6 SMO SMO BAK1 BAK1 DLL1 DLL1 EFNA1 EFNA1 RNASE4 RNASE4 FKBP10 FKBP10 JAG1 JAG1 MMRN2 MMRN2 AMOTL1 AMOTL1 ADTRP ADTRP CCN3 CCN3 NF1 NF1 VSTM4 VSTM4 COMP COMP TAL1 TAL1 LOC101101103 LOC101101103 CCN2 CCN2 CCDC134 CCDC134 SEMA4A SEMA4A ADGRG1 ADGRG1 MYO18B MYO18B COL18A1 COL18A1 ADGRF5 ADGRF5 FGF1 FGF1 HOXA13 HOXA13 ITGAV ITGAV HES1 HES1 BMP4 BMP4 CXCL17 CXCL17 LDLR LDLR APOLD1 APOLD1 VEGFA VEGFA HS6ST1 HS6ST1 NFATC4 NFATC4 COL22A1 COL22A1 YAP1 YAP1 HPSE HPSE MYOCD MYOCD ANPEP ANPEP ADGRA2 ADGRA2 PKNOX1 PKNOX1 LEF1 LEF1 NRP2 NRP2 GLUL GLUL FGF18 FGF18 MYO1E MYO1E TGFBR1 TGFBR1 CALCRL CALCRL AMOTL2 AMOTL2 PDCL3 PDCL3 SHB SHB ANGPT1 ANGPT1 PIK3R3 PIK3R3 NOG NOG HOXA3 HOXA3 HDAC7 HDAC7 PGF PGF ZFPM2 ZFPM2 C1GALT1 C1GALT1 MED1 MED1 CLIC4 CLIC4 HAND2 HAND2 APLN APLN THY1 THY1 VASH1 VASH1 SMAD7 SMAD7 CYP1B1 CYP1B1 ARID2 ARID2 EPHB1 EPHB1 GLMN GLMN XBP1 XBP1 SOX18 SOX18 RASA1 RASA1 TGFA TGFA EDNRA EDNRA SOX17 SOX17 SLIT2 SLIT2 RORA RORA EPGN EPGN SFRP2 SFRP2 LEPR LEPR NDNF NDNF FLNA FLNA PRDM1 PRDM1 ADAM8 ADAM8 NRCAM NRCAM EPHB4 EPHB4 HEY2 HEY2 MYDGF MYDGF PXDN PXDN QKI QKI GAB1 GAB1 ACVRL1 ACVRL1 PIK3CA PIK3CA CALD1 CALD1 CNRIP1 CNRIP1 STRA6 STRA6 SGCD SGCD SETD2 SETD2 GBX2 GBX2 PTPRB PTPRB PTK2 PTK2 PANK2 PANK2 HAS2 HAS2 LEP LEP FGF10 FGF10 NRARP NRARP FBXW9 FBXW9 EPHB2 EPHB2 ITGB1 ITGB1 FZD4 FZD4 PROK2 PROK2 ITGB1BP1 ITGB1BP1 RNF213 RNF213 APELA APELA CAV1 CAV1 SAT1 SAT1 SIRT1 SIRT1 FLT1 FLT1 IL18 IL18 GJC1 GJC1 PKD2 PKD2 JAM3 JAM3 TBX4 TBX4 BMPR1A BMPR1A ADIPOR2 ADIPOR2 CIB1 CIB1 ZFP36L1 ZFP36L1 PDCD10 PDCD10 APOB APOB GNA13 GNA13 KLF5 KLF5 CITED2 CITED2 SOS1 SOS1 ANGPT4 ANGPT4 FGF9 FGF9 TCF21 TCF21 JUN JUN NPRL3 NPRL3 M3X1N0_FELCA M3X1N0_FELCA ADRA2B ADRA2B FOXH1 FOXH1 ESM1 ESM1 WNT11 WNT11 NOTCH1 NOTCH1 SRF SRF HOXA7 HOXA7 STK4 STK4 PTK2B PTK2B CCN1 CCN1 HEY1 HEY1 PRCP PRCP KRIT1 KRIT1 GPR15 GPR15 B4GALT1 B4GALT1 CXCR3 CXCR3 IHH IHH SEMA3E SEMA3E FOXF1 FOXF1 TSPAN12 TSPAN12 JUNB JUNB SCG2 SCG2 POFUT1 POFUT1 PRKX PRKX PROX1 PROX1 PTEN PTEN TFAP2B TFAP2B EFNB2 EFNB2 ANGPTL4 ANGPTL4 TIE1 TIE1 HEG1 HEG1 HAND1 HAND1 EDN1 EDN1 COL3A1 COL3A1 DLL4 DLL4 ANGPT2 ANGPT2 TGFBI TGFBI YJEFN3 YJEFN3 SYK SYK BMPR2 BMPR2 PLEKHH1 PLEKHH1 EDN2 EDN2 TFAP2E TFAP2E EPAS1 EPAS1 TIPARP TIPARP TBX20 TBX20 RECK RECK EIF2AK3 EIF2AK3 ACKR3 ACKR3 AMOT AMOT LOXL2 LOXL2 SPRED1 SPRED1 COL15A1 COL15A1 ATP5F1B ATP5F1B PRKCA PRKCA CCM2 CCM2 ZMIZ1 ZMIZ1 THBS1 THBS1 ANGPTL3 ANGPTL3 PARVA PARVA GPLD1 GPLD1 PLXDC2 PLXDC2 E2F7 E2F7 ELK3 ELK3 E2F8 E2F8 EPHA2 EPHA2 ITGA5 ITGA5 PLXDC1 PLXDC1 CUL7 CUL7 KDR KDR NOTCH2 NOTCH2 RAMP2 RAMP2 RSPO3 RSPO3 PDGFRA PDGFRA NTRK2 NTRK2 TBX2 TBX2 EPHB3 EPHB3 ZC3H12A ZC3H12A LAMA1 LAMA1 PAXIP1 PAXIP1 FOXN1 FOXN1 VEGFC VEGFC WASF2 WASF2 WARS2 WARS2 RASIP1 RASIP1 LOXL3 LOXL3 NOX1 NOX1 ITGB8 ITGB8 ROBO4 ROBO4 MFGE8 MFGE8 NAXE NAXE HOXB3 HOXB3 SERPINF2 SERPINF2 NRP1 NRP1 UBP1 UBP1 LRP2 LRP2 OTULIN OTULIN VEGFB VEGFB EGR3 EGR3 PLCD3 PLCD3 PXDNL PXDNL HPGD HPGD CDH13 CDH13 CHD7 CHD7 CLEC14A CLEC14A PDGFRB PDGFRB EMCN EMCN HIF1A HIF1A SRPX2 SRPX2 ITGA2B ITGA2B TEK TEK AAMP AAMP NR2E1 NR2E1 HOXB13 HOXB13 FLT4 FLT4 TEAD2 TEAD2 ENG ENG SHC1 SHC1 SGPL1 SGPL1 MYH9 MYH9 MCAM MCAM BMPER BMPER TMEM100 TMEM100 FBXW7 FBXW7 GJA5 GJA5 EMC10 EMC10 EYA1 EYA1 PLXND1 PLXND1 SEC24B SEC24B
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa)
ETV2ETS variant 2. (249 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (546 aa)
ENSFCAP00000060656N-acetyltransferase domain-containing protein. (103 aa)
ANGPTL6Angiopoietin like 6. (546 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa)
BAK1BCL2 antagonist/killer 1. (251 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (357 aa)
RNASE4Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (189 aa)
FKBP10Peptidylprolyl isomerase. (628 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1287 aa)
MMRN2Multimerin 2. (1005 aa)
AMOTL1Angiomotin like 1. (1038 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
CCN3Cellular communication network factor 3. (394 aa)
NF1Neurofibromin 1. (2856 aa)
VSTM4V-set and transmembrane domain containing 4. (389 aa)
COMPCartilage oligomeric matrix protein. (804 aa)
TAL1TAL bHLH transcription factor 1, erythroid differentiation factor. (414 aa)
LOC101101103Uncharacterized protein. (1668 aa)
CCN2Cellular communication network factor 2. (477 aa)
CCDC134Coiled-coil domain containing 134. (230 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (806 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (689 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2584 aa)
COL18A1Collagen type XVIII alpha 1 chain. (1518 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1387 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (170 aa)
HOXA13Homeobox A13. (389 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
LDLRLow density lipoprotein receptor. (866 aa)
APOLD1Apolipoprotein L domain containing 1. (279 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (450 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (411 aa)
NFATC4Nuclear factor of activated T cells 4. (930 aa)
COL22A1VWFA domain-containing protein. (1310 aa)
YAP1Yes associated protein 1. (498 aa)
HPSEHeparanase. (543 aa)
MYOCDMyocardin. (962 aa)
ANPEPAminopeptidase N; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding [...] (1014 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1336 aa)
PKNOX1Homeobox domain-containing protein. (436 aa)
LEF1Lymphoid enhancer binding factor 1. (415 aa)
NRP2Neuropilin 2. (992 aa)
GLULGlutamine synthetase. (506 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1145 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (463 aa)
AMOTL2Angiomotin like 2. (835 aa)
PDCL3Phosducin like 3. (240 aa)
SHBSH2 domain-containing protein. (508 aa)
ANGPT1Angiopoietin 1. (498 aa)
PIK3R3Uncharacterized protein. (461 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HOXA3Homeobox A3. (441 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1070 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (367 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
HAND2Heart and neural crest derivatives expressed 2. (275 aa)
APLNApelin. (77 aa)
THY1Thy-1 cell surface antigen. (161 aa)
VASH1Vasohibin 1. (446 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (553 aa)
ARID2AT-rich interaction domain 2. (1874 aa)
EPHB1EPH receptor B1. (984 aa)
GLMNGlomulin, FKBP associated protein. (600 aa)
XBP1X-box binding protein 1. (383 aa)
SOX18SRY-box transcription factor 18. (465 aa)
RASA1RAS p21 protein activator 1. (1039 aa)
TGFATransforming growth factor alpha. (192 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SOX17SRY-box transcription factor 17. (406 aa)
SLIT2Slit guidance ligand 2. (1543 aa)
RORARAR related orphan receptor A. (523 aa)
EPGNEpithelial mitogen. (153 aa)
SFRP2Secreted frizzled related protein 2. (385 aa)
LEPRLeptin receptor. (1166 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
FLNAFilamin A. (2808 aa)
PRDM1PR/SET domain 1. (821 aa)
ADAM8ADAM metallopeptidase domain 8. (872 aa)
NRCAMNeuronal cell adhesion molecule. (1211 aa)
EPHB4EPH receptor B4. (987 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MYDGFMyeloid derived growth factor. (173 aa)
PXDNPeroxidasin. (1502 aa)
QKIProtein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). (341 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
CALD1Caldesmon 1. (831 aa)
CNRIP1Uncharacterized protein. (324 aa)
STRA6Stimulated by retinoic acid 6. (700 aa)
SGCDSarcoglycan delta. (289 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2563 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2215 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1112 aa)
PANK2Pantothenate kinase 2. (570 aa)
HAS2Hyaluronan synthase 2. (552 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
EPHB2EPH receptor B2. (899 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
PROK2Prokineticin 2. (125 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (213 aa)
RNF213Ring finger protein 213. (5273 aa)
APELAUncharacterized protein. (54 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
SAT1N-acetyltransferase domain-containing protein. (171 aa)
SIRT1Sirtuin 1. (745 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (970 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
TBX4T-box transcription factor 4. (553 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
CIB1Calcium and integrin binding 1. (191 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
PDCD10Programmed cell death 10. (212 aa)
APOBApolipoprotein B. (4441 aa)
GNA13G protein subunit alpha 13. (377 aa)
KLF5Kruppel like factor 5. (457 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
ANGPT4Angiopoietin 4. (499 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TCF21Transcription factor 21. (179 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
M3X1N0_FELCAUncharacterized protein. (276 aa)
ADRA2BAdrenoceptor alpha 2B. (444 aa)
FOXH1Forkhead box H1. (361 aa)
ESM1Endothelial cell specific molecule 1. (182 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
NOTCH1Notch receptor 1. (2543 aa)
SRFSerum response factor. (512 aa)
HOXA7Homeobox A7. (234 aa)
STK4Serine/threonine kinase 4. (487 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
CCN1Cellular communication network factor 1. (382 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
PRCPProlylcarboxypeptidase. (548 aa)
KRIT1KRIT1 ankyrin repeat containing. (736 aa)
GPR15G protein-coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (333 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (400 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (775 aa)
FOXF1Forkhead box F1. (459 aa)
TSPAN12Tetraspanin. (314 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
SCG2Secretogranin II. (680 aa)
POFUT1Protein O-fucosyltransferase 1. (391 aa)
PRKXUncharacterized protein. (416 aa)
PROX1Prospero homeobox 1. (737 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
ANGPTL4Angiopoietin like 4. (414 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1137 aa)
HEG1Heart development protein with EGF like domains 1. (1374 aa)
HAND1Heart and neural crest derivatives expressed 1. (218 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (699 aa)
ANGPT2Angiopoietin 2. (494 aa)
TGFBITransforming growth factor beta induced. (683 aa)
YJEFN3YjeF N-terminal domain-containing protein. (250 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PLEKHH1Pleckstrin homology, MyTH4 and FERM domain containing H1. (1365 aa)
EDN2Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (178 aa)
TFAP2ETranscription factor AP-2 epsilon. (441 aa)
EPAS1Endothelial PAS domain protein 1. (872 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (692 aa)
TBX20T-box transcription factor 20. (480 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (971 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (406 aa)
AMOTAngiomotin. (1075 aa)
LOXL2Lysyl oxidase like 2. (773 aa)
SPRED1Sprouty related EVH1 domain containing 1. (443 aa)
COL15A1Collagen type XV alpha 1 chain. (1372 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (784 aa)
CCM2CCM2 scaffold protein. (453 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1066 aa)
THBS1Thrombospondin 1. (1170 aa)
ANGPTL3Angiopoietin like 3. (460 aa)
PARVAParvin alpha. (372 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (873 aa)
PLXDC2Plexin domain containing 2. (529 aa)
E2F7E2F transcription factor 7. (910 aa)
ELK3ETS transcription factor ELK3. (402 aa)
E2F8E2F transcription factor 8. (864 aa)
EPHA2EPH receptor A2. (936 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1104 aa)
PLXDC1Plexin domain containing 1. (500 aa)
CUL7Cullin 7; Belongs to the cullin family. (1695 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa)
NOTCH2Notch receptor 2. (2493 aa)
RAMP2Receptor activity modifying protein 2. (206 aa)
RSPO3R-spondin 3. (279 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
TBX2T-box transcription factor 2. (713 aa)
EPHB3EPH receptor B3. (1000 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (582 aa)
LAMA1Laminin subunit alpha 1. (3080 aa)
PAXIP1PAX interacting protein 1. (1016 aa)
FOXN1Forkhead box N1. (646 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
WASF2WASP family member 2. (498 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
RASIP1Ras interacting protein 1. (943 aa)
LOXL3Lysyl oxidase like 3. (974 aa)
NOX1NADPH oxidase 1. (564 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
ROBO4Roundabout guidance receptor 4. (1007 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (430 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (301 aa)
HOXB3Homeobox B3. (359 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (565 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
UBP1Upstream binding protein 1. (539 aa)
LRP2LDL receptor related protein 2. (4646 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (360 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
EGR3Early growth response 3. (392 aa)
PLCD3Phosphoinositide phospholipase C. (777 aa)
PXDNLPeroxidasin like. (1457 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (265 aa)
CDH13Cadherin 13. (713 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2995 aa)
CLEC14AC-type lectin domain containing 14A. (489 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1131 aa)
EMCNEndomucin. (259 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (825 aa)
SRPX2Sushi repeat containing protein X-linked 2. (464 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1086 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
AAMPAngio associated migratory cell protein. (449 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
HOXB13Homeobox B13. (285 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1405 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
ENGEndoglin. (654 aa)
SHC1SHC adaptor protein 1. (566 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (671 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1981 aa)
MCAMMelanoma cell adhesion molecule. (681 aa)
BMPERBMP binding endothelial regulator. (685 aa)
TMEM100Transmembrane protein 100. (134 aa)
FBXW7F-box and WD repeat domain containing 7. (749 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
EMC10ER membrane protein complex subunit 10. (262 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
PLXND1Plexin D1. (1927 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1259 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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