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| | PLAG1 | PLAG1 zinc finger. (499 aa) |
| | TRIM28 | Tripartite motif containing 28. (821 aa) |
| | PLXNA3 | Plexin A3. (1872 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1407 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (700 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa) |
| | STK3 | Serine/threonine kinase 3. (573 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (674 aa) |
| | ANXA1 | Annexin. (407 aa) |
| | CPNE1 | Copine 1. (542 aa) |
| | ETNK2 | Ethanolamine kinase 2. (425 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa) |
| | TBCE | Uncharacterized protein. (547 aa) |
| | GAS1 | Growth arrest specific 1. (369 aa) |
| | SCAPER | S-phase cyclin A associated protein in the ER. (1401 aa) |
| | ARIH2 | RBR-type E3 ubiquitin transferase. (501 aa) |
| | ENSFCAP00000057272 | Uncharacterized protein. (2518 aa) |
| | ANXA6 | Annexin. (723 aa) |
| | FLRT3 | Fibronectin leucine rich transmembrane protein 3. (649 aa) |
| | IFRD2 | Interferon related developmental regulator 2. (495 aa) |
| | PRKCZ | Protein kinase C zeta. (649 aa) |
| | NDEL1 | NudE neurodevelopment protein 1 like 1. (480 aa) |
| | CPLX1 | Complexin 1. (178 aa) |
| | COMP | Cartilage oligomeric matrix protein. (804 aa) |
| | ANKRD26 | ANK_REP_REGION domain-containing protein. (266 aa) |
| | RASAL2 | RAS protein activator like 2. (1459 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1251 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (867 aa) |
| | SLC1A2 | Amino acid transporter. (579 aa) |
| | SHBG | Sex hormone binding globulin. (400 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1335 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (783 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (170 aa) |
| | MYMK | Myomaker, myoblast fusion factor. (221 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (564 aa) |
| | RARG | Retinoic acid receptor gamma. (459 aa) |
| | PTX3 | Pentraxin 3. (381 aa) |
| | CER1 | Cerberus 1, DAN family BMP antagonist. (270 aa) |
| | SP2 | Sp2 transcription factor. (640 aa) |
| | AKIRIN1 | Akirin 1. (192 aa) |
| | SLC12A5 | Solute carrier family 12 member 5. (1196 aa) |
| | MYMX | Myomixer, myoblast fusion factor. (84 aa) |
| | LOC101093046 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (208 aa) |
| | YAP1 | Yes associated protein 1. (498 aa) |
| | BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (255 aa) |
| | HOXA5 | Homeobox A5. (381 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (569 aa) |
| | UNC79 | Unc-79 homolog, NALCN channel complex subunit. (2656 aa) |
| | EMX1 | Empty spiracles homeobox 1. (296 aa) |
| | SEMA5B | Semaphorin 5B. (1100 aa) |
| | LGR6 | LRRNT domain-containing protein. (967 aa) |
| | NRP2 | Neuropilin 2. (992 aa) |
| | TAF8 | TATA-box binding protein associated factor 8. (410 aa) |
| | ATF5 | Activating transcription factor 5. (280 aa) |
| | AUTS2 | Activator of transcription and developmental regulator AUTS2. (1258 aa) |
| | BIN3 | Bridging integrator 3. (352 aa) |
| | GJE1 | Gap junction protein epsilon 1. (205 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1344 aa) |
| | RBBP6 | RB binding protein 6, ubiquitin ligase. (1792 aa) |
| | GALK1 | Galactokinase 1. (619 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1132 aa) |
| | SOX9 | SRY-box transcription factor 9. (511 aa) |
| | LOC101092676 | TGF_BETA_2 domain-containing protein. (410 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa) |
| | TENM4 | Teneurin transmembrane protein 4. (2823 aa) |
| | HDAC6 | Histone deacetylase 6. (1178 aa) |
| | RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1. (650 aa) |
| | SLC25A25 | Solute carrier family 25 member 25; Belongs to the mitochondrial carrier (TC 2.A.29) family. (513 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ANKRD12 | Ankyrin repeat domain 12. (2060 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | CLIC4 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa) |
| | APBA1 | Amyloid beta precursor protein binding family A member 1. (831 aa) |
| | ARID2 | AT-rich interaction domain 2. (1874 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | TM4SF4 | Transmembrane 4 L six family member 4. (202 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | EN1 | Homeobox protein engrailed-like. (396 aa) |
| | ARX | Aristaless related homeobox. (562 aa) |
| | MED12 | Mediator complex subunit 12. (2278 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (329 aa) |
| | RAD51B | RAD51 paralog B. (350 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | SEMA5A | Semaphorin 5A. (1116 aa) |
| | SLIT2 | Slit guidance ligand 2. (1543 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (385 aa) |
| | LEPR | Leptin receptor. (1166 aa) |
| | HELT | Helt bHLH transcription factor. (242 aa) |
| | LHX1 | LIM homeobox 1. (406 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (588 aa) |
| | CD9 | CD9 antigen; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, [...] (250 aa) |
| | LRP4 | LDL receptor related protein 4. (1905 aa) |
| | RAG2 | Recombination activating 2. (527 aa) |
| | COBL | Cordon-bleu WH2 repeat protein. (395 aa) |
| | DCLK1 | Doublecortin like kinase 1. (741 aa) |
| | TEC | Tyrosine-protein kinase. (650 aa) |
| | HOXA11 | Homeobox A11. (327 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (406 aa) |
| | PELO | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa) |
| | TBX5 | T-box transcription factor 5. (518 aa) |
| | TNN | Tenascin N. (1120 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | STRA6 | Stimulated by retinoic acid 6. (700 aa) |
| | SALL4 | Spalt like transcription factor 4. (1058 aa) |
| | BNC2 | Basonuclin 2. (1115 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | DDR2 | Discoidin domain receptor tyrosine kinase 2. (866 aa) |
| | LIMK1 | LIM domain kinase 1. (763 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (457 aa) |
| | STK40 | Serine/threonine kinase 40. (491 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) |
| | IL7 | Interleukin 7. (158 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | SAV1 | Salvador family WW domain containing protein 1. (395 aa) |
| | HLX | H2.0 like homeobox. (569 aa) |
| | ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa) |
| | MEX3C | Mex-3 RNA binding family member C. (657 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | GAS2 | Growth arrest specific 2. (314 aa) |
| | ALKBH1 | AlkB homolog 1, histone H2A dioxygenase. (352 aa) |
| | KIF26B | Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1970 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | IST1 | IST1 factor associated with ESCRT-III. (366 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (395 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa) |
| | SPART | Spartin. (672 aa) |
| | LOC101092829 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (165 aa) |
| | ENSFCAP00000026835 | Uncharacterized protein. (73 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa) |
| | GAP43 | Neuromodulin; This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction (By similarity). (242 aa) |
| | LZTS2 | Leucine zipper tumor suppressor 2. (645 aa) |
| | NDN | Necdin, MAGE family member. (324 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | BMP10 | TGF_BETA_2 domain-containing protein. (424 aa) |
| | G6PC | Glucose-6-phosphatase; Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels (By similarity). Belongs to the glucose-6-phosphatase family. (357 aa) |
| | NIN | Ninein. (2128 aa) |
| | CDKL3 | Cyclin dependent kinase like 3. (581 aa) |
| | IMPACT | Impact RWD domain protein. (331 aa) |
| | HOXD13 | Homeobox D13. (341 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1484 aa) |
| | JADE2 | Jade family PHD finger 2. (827 aa) |
| | ADD1 | Adducin 1. (761 aa) |
| | VCL | Vinculin. (1066 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | GATA6 | GATA binding protein 6. (646 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (834 aa) |
| | TNFAIP6 | TNF alpha induced protein 6. (277 aa) |
| | ATN1 | Atrophin 1. (1193 aa) |
| | KLF5 | Kruppel like factor 5. (457 aa) |
| | ASPM | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3478 aa) |
| | MUSTN1 | Uncharacterized protein. (86 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (378 aa) |
| | APOD | Apolipoprotein D. (189 aa) |
| | GPR149 | G protein-coupled receptor 149. (747 aa) |
| | NRN1 | Neuritin 1. (142 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa) |
| | FOXO3 | Forkhead box O3. (672 aa) |
| | FXN | Frataxin. (211 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa) |
| | PTN | Pleiotrophin. (179 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | HESX1 | HESX homeobox 1. (207 aa) |
| | SBDS | SBDS ribosome maturation factor. (250 aa) |
| | WDR48 | WD repeat domain 48. (677 aa) |
| | OSTN | Osteocrin. (132 aa) |
| | SSNA1 | SS nuclear autoantigen 1. (119 aa) |
| | LOC101082908 | Uncharacterized protein. (591 aa) |
| | TMEM108 | Transmembrane protein 108. (581 aa) |
| | DIPK2A | Divergent protein kinase domain 2A. (430 aa) |
| | NRN1L | Neuritin 1 like. (169 aa) |
| | MTM1 | Myotubularin 1. (603 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa) |
| | LLPH | LLP homolog, long-term synaptic facilitation factor. (127 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | H3F3A | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | TMEM182 | Transmembrane protein 182. (229 aa) |
| | NOTCH1 | Notch receptor 1. (2543 aa) |
| | SRF | Serum response factor. (512 aa) |
| | BRCA2 | Breast cancer type 2 susceptibility protein homolog; Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51- ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint acti [...] (3375 aa) |
| | STK4 | Serine/threonine kinase 4. (487 aa) |
| | MATN1 | Matrilin 1. (539 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | TMEM38B | Transmembrane protein 38B. (409 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | KDF1 | Keratinocyte differentiation factor 1. (397 aa) |
| | ATRX | ATRX chromatin remodeler. (2486 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | ECM1 | Extracellular matrix protein 1. (562 aa) |
| | CPQ | Carboxypeptidase Q. (472 aa) |
| | WASF1 | WASP family member 1. (570 aa) |
| | MSTN | Myostatin. (375 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | NINJ1 | Ninjurin 1. (151 aa) |
| | CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa) |
| | HEG1 | Heart development protein with EGF like domains 1. (1374 aa) |
| | RMI1 | RecQ mediated genome instability 1. (635 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1466 aa) |
| | TNR | Tenascin R. (1358 aa) |
| | TXK | Tyrosine-protein kinase. (551 aa) |
| | ADPRHL1 | ADP-ribosylhydrolase like 1. (354 aa) |
| | EDN2 | Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (178 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (362 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | KDM5B | Lysine demethylase 5B. (1544 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (232 aa) |
| | SELENON | Selenoprotein N. (556 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (710 aa) |
| | NPPC | Natriuretic peptide C. (193 aa) |
| | GDF9 | Growth differentiation factor 9. (452 aa) |
| | PATL2 | SPG11 vesicle trafficking associated, spatacsin. (2444 aa) |
| | GLI3 | GLI family zinc finger 3. (1578 aa) |
| | DMBX1 | Diencephalon/mesencephalon homeobox 1. (374 aa) |
| | ZPR1 | ZPR1 zinc finger. (459 aa) |
| | CCM2 | CCM2 scaffold protein. (453 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1066 aa) |
| | TTC8 | Tetratricopeptide repeat domain 8. (515 aa) |
| | SLIT3 | Slit guidance ligand 3. (1530 aa) |
| | ULK1 | Unc-51 like autophagy activating kinase 1. (1113 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa) |
| | DDR1 | Discoidin domain receptor tyrosine kinase 1. (921 aa) |
| | RARB | Retinoic acid receptor beta. (448 aa) |
| | LAMB2 | Laminin subunit beta 2. (1801 aa) |
| | PTK7 | Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa) |
| | NOTCH2 | Notch receptor 2. (2493 aa) |
| | SOX15 | SRY-box 15. (233 aa) |
| | KDM6A | Lysine demethylase 6A. (1453 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1139 aa) |
| | TBX2 | T-box transcription factor 2. (713 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (261 aa) |
| | NINJ2 | Ninjurin 2. (190 aa) |
| | LPAR3 | Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (383 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa) |
| | SEMA7A | Semaphorin 7A; Belongs to the semaphorin family. (769 aa) |
| | TARBP2 | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | INTS1 | Integrator complex subunit 1. (2186 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (700 aa) |
| | SPTBN2 | Spectrin beta chain; Belongs to the spectrin family. (2418 aa) |
| | ALCAM | Activated leukocyte cell adhesion molecule. (583 aa) |
| | SEMA3F | Semaphorin 3F; Belongs to the semaphorin family. (785 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | LHX2 | LIM homeobox 2. (406 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (276 aa) |
| | THBS3 | Thrombospondin 3. (955 aa) |
| | HDGFL2 | HDGF like 2. (671 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | CHRND | Cholinergic receptor nicotinic delta subunit. (517 aa) |
| | SPAG6 | Sperm associated antigen 6. (509 aa) |
| | MAP1B | Microtubule associated protein 1B. (2471 aa) |
| | IFT80 | Intraflagellar transport 80. (777 aa) |
| | EP300 | E1A binding protein p300. (2425 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa) |
| | CCDC151 | Coiled-coil domain containing 151. (595 aa) |
| | DCX | Doublecortin. (365 aa) |
| | SGCA | Sarcoglycan alpha. (439 aa) |
| | SLC4A10 | Anion exchange protein. (1118 aa) |
| | ENSFCAP00000003985 | Uncharacterized protein. (184 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | EVC | EvC ciliary complex subunit 1. (943 aa) |
| | NIPBL | Nipped-B protein. (2805 aa) |
| | CTNNB1 | Catenin beta 1. (783 aa) |
| | PKDCC | Protein kinase domain containing, cytoplasmic. (494 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | RYK | Receptor like tyrosine kinase. (609 aa) |
| | SOX10 | SRY-box transcription factor 10. (604 aa) |
| | SLIT1 | Slit guidance ligand 1. (1518 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa) |
| | SLITRK1 | SLIT and NTRK like family member 1. (696 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (836 aa) |
| | PTGFRN | Prostaglandin F2 receptor inhibitor. (995 aa) |
| | CD4H9orf72 | Chromosome D4 C9orf72 homolog. (481 aa) |
| | CTC1 | CST telomere replication complex component 1. (1218 aa) |
| | APP | Amyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa) |
| | SELENOM | Selenoprotein M. (141 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (692 aa) |
| | CHCHD6 | MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa) |
| | CTR9 | CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa) |
| | AREG | Amphiregulin. (323 aa) |
| | TNS2 | Tensin 2. (1409 aa) |
| | FLVCR1 | Feline leukemia virus subgroup C receptor-related protein 1; Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and is required to maintain intracellular free heme balance, protecting cells from heme toxicity. Heme export provides protection from heme or ferrous iron toxicities in liver, brain, sensory neurons and during erythtopoiesis, a process in which heme synthesis intensifies (By similari [...] (560 aa) |
| | MMP13 | Matrix metallopeptidase 13. (470 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa) |
