STRINGSTRING
TREM2 TREM2 NF1 NF1 NR1D1 NR1D1 HES1 HES1 LDLR LDLR NOG NOG HES5 HES5 BIN1 BIN1 LIF LIF BMP2 BMP2 NOTCH1 NOTCH1 F2 F2 CLCF1 CLCF1 IL6ST IL6ST EPHA4 EPHA4 CNTN2 CNTN2 SERPINE2 SERPINE2 NR2E1 NR2E1 GPR37L1 GPR37L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TREM2Triggering receptor expressed on myeloid cells 2. (258 aa)
NF1Neurofibromin 1. (2856 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (625 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
LDLRLow density lipoprotein receptor. (866 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
BIN1Bridging integrator 1. (608 aa)
LIFLIF interleukin 6 family cytokine. (204 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
NOTCH1Notch receptor 1. (2543 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
CLCF1Cardiotrophin like cytokine factor 1. (340 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
EPHA4EPH receptor A4. (986 aa)
CNTN2Contactin 2. (1103 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (484 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
GPR37L1G protein-coupled receptor 37 like 1. (551 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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