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| | PLXND1 | Plexin D1. (1927 aa) |
| | HNF1B | HNF1 homeobox B. (558 aa) |
| | AREG | Amphiregulin. (323 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | ELF3 | E74 like ETS transcription factor 3. (370 aa) |
| | NKX2-5 | NK2 homeobox 5. (333 aa) |
| | CSN2 | Beta-casein; Important role in determination of the surface properties of the casein micelles. (223 aa) |
| | CHCHD6 | MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa) |
| | SCRIB | Scribble planar cell polarity protein. (1637 aa) |
| | NODAL | Nodal growth differentiation factor. (348 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (421 aa) |
| | GCM2 | Glial cells missing transcription factor 2. (505 aa) |
| | CTC1 | CST telomere replication complex component 1. (1218 aa) |
| | ASXL1 | ASXL transcriptional regulator 1. (1545 aa) |
| | GLI1 | GLI family zinc finger 1. (1105 aa) |
| | HOXB13 | Homeobox B13. (285 aa) |
| | STAT5B | Signal transducer and activator of transcription. (786 aa) |
| | POU1F1 | POU domain protein. (291 aa) |
| | CSMD2 | CUB and Sushi multiple domains 2. (3632 aa) |
| | GHRHR | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa) |
| | SLC6A3 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (656 aa) |
| | SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (484 aa) |
| | SOX10 | SRY-box transcription factor 10. (604 aa) |
| | PML | Promyelocytic leukemia. (876 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (825 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (429 aa) |
| | RHBDD3 | Rhomboid domain containing 3. (393 aa) |
| | PAX1 | Paired box 1. (446 aa) |
| | PRKCSH | Protein kinase C substrate 80K-H. (538 aa) |
| | TNC | Tenascin C. (2200 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (916 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | RIPK3 | Receptor interacting serine/threonine kinase 3. (509 aa) |
| | WDR77 | WD repeat domain 77. (342 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (342 aa) |
| | BSX | Brain specific homeobox. (232 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (417 aa) |
| | HOXB3 | Homeobox B3. (359 aa) |
| | IQGAP3 | IQ motif containing GTPase activating protein 3. (1630 aa) |
| | GHRH | Growth hormone releasing hormone. (106 aa) |
| | PAX6 | Paired box 6. (437 aa) |
| | C6orf58 | Chromosome 6 open reading frame 58. (328 aa) |
| | CLCN2 | Chloride channel protein. (903 aa) |
| | AIRE | Autoimmune regulator. (549 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | CCDC40 | Coiled-coil domain containing 40. (1152 aa) |
| | FOXN1 | Forkhead box N1. (646 aa) |
| | SERPINB5 | Serpin family B member 5; Belongs to the serpin family. (379 aa) |
| | GFER | Sulfhydryl oxidase. (408 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (460 aa) |
| | LAMA1 | Laminin subunit alpha 1. (3080 aa) |
| | NKX2-2 | NK2 homeobox 2. (273 aa) |
| | EPHB3 | EPH receptor B3. (1000 aa) |
| | TBX2 | T-box transcription factor 2. (713 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (504 aa) |
| | MAN2A1 | Alpha-mannosidase. (1145 aa) |
| | HNF1A | HNF1 homeobox A. (639 aa) |
| | NOTCH2 | Notch receptor 2. (2493 aa) |
| | EPHA2 | EPH receptor A2. (936 aa) |
| | RB1CC1 | RB1 inducible coiled-coil 1. (1593 aa) |
| | DDR1 | Discoidin domain receptor tyrosine kinase 1. (921 aa) |
| | E2F8 | E2F transcription factor 8. (864 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | E2F7 | E2F transcription factor 7. (910 aa) |
| | CSF1 | Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa) |
| | IGSF3 | Immunoglobulin superfamily member 3. (1209 aa) |
| | DNAAF1 | Dynein assembly factor 1, axonemal. (641 aa) |
| | FASN | Fatty acid synthase. (2655 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | GLI3 | GLI family zinc finger 3. (1578 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | GPAT4 | Glycerol-3-phosphate acyltransferase 4. (456 aa) |
| | KDM5B | Lysine demethylase 5B. (1544 aa) |
| | FRZB | Frizzled related protein. (324 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa) |
| | MSN | Moesin. (577 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | CSN3 | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family. (182 aa) |
| | STAT6 | Signal transducer and activator of transcription. (844 aa) |
| | AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1195 aa) |
| | EDN1 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa) |
| | PRL | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. (229 aa) |
| | IRF6 | Interferon regulatory factor 6. (480 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa) |
| | EAF2 | ELL associated factor 2. (264 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ZNF330 | Zinc finger protein 330. (459 aa) |
| | ZBTB7B | Uncharacterized protein. (540 aa) |
| | SALL1 | Spalt like transcription factor 1. (1238 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (524 aa) |
| | NR0B1 | Nuclear receptor subfamily 0 group B member 1. (471 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | SRP54 | Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa) |
| | FOXF1 | Forkhead box F1. (459 aa) |
| | SP3 | Sp3 transcription factor. (713 aa) |
| | SEMA3C | Semaphorin 3C; Belongs to the semaphorin family. (749 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (574 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | SRF | Serum response factor. (512 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (785 aa) |
| | NOTCH1 | Notch receptor 1. (2543 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | UPF2 | UPF2 regulator of nonsense mediated mRNA decay. (1272 aa) |
| | ESR1 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa) |
| | TYR | Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. Belongs to the tyrosinase family. (529 aa) |
| | FOXA1 | Forkhead box A1. (536 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | LOC101091873 | Uncharacterized protein. (337 aa) |
| | VDR | Vitamin D receptor. (441 aa) |
| | PHB2 | Prohibitin. (299 aa) |
| | TPH1 | Tryptophan hydroxylase 1. (527 aa) |
| | TCF21 | Transcription factor 21. (179 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1127 aa) |
| | HESX1 | HESX homeobox 1. (207 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa) |
| | GSX1 | GS homeobox 1. (264 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (834 aa) |
| | GATA6 | GATA binding protein 6. (646 aa) |
| | FOXB1 | Forkhead box B1. (325 aa) |
| | ORAI1 | ORAI calcium release-activated calcium modulator 1. (406 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa) |
| | ACADM | Acyl-CoA dehydrogenase medium chain. (445 aa) |
| | HOXD13 | Homeobox D13. (341 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa) |
| | PKD2 | Polycystin 2, transient receptor potential cation channel. (970 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | ZDHHC21 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (299 aa) |
| | LOC101092829 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (165 aa) |
| | HOXD3 | Homeobox D3. (432 aa) |
| | ONECUT2 | One cut domain family member. (504 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | CSMD1 | CUB and Sushi multiple domains 1. (3501 aa) |
| | DDX55 | RNA helicase. (600 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | PDX1 | Pancreatic and duodenal homeobox 1. (282 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | ARMC5 | Armadillo repeat containing 5. (943 aa) |
| | HLX | H2.0 like homeobox. (569 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | LSR | Lipolysis stimulated lipoprotein receptor. (647 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) |
| | CACNB4 | Calcium voltage-gated channel auxiliary subunit beta 4. (519 aa) |
| | SELENOH | Selenoprotein H. (121 aa) |
| | NKX2-1 | NK2 homeobox 1. (399 aa) |
| | HGF | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity). (728 aa) |
| | HOXB9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (251 aa) |
| | SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (366 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (457 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ATP2C2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (962 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | STRA6 | Stimulated by retinoic acid 6. (700 aa) |
| | ASH1L | ASH1 like histone lysine methyltransferase. (2965 aa) |
| | NRG3 | Neuregulin 3. (720 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | PAX8 | Paired box 8. (620 aa) |
| | PYGO2 | Pygopus family PHD finger 2. (406 aa) |
| | HOXD9 | Homeobox D9. (345 aa) |
| | COBL | Cordon-bleu WH2 repeat protein. (395 aa) |
| | CRADD | Uncharacterized protein. (398 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2. (726 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (206 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (543 aa) |
| | ZNF703 | Zinc finger protein 703. (592 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (416 aa) |
| | NR5A2 | Nuclear receptor subfamily 5 group A member 2. (541 aa) |
| | BCL11B | Uncharacterized protein. (895 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | TGFA | Transforming growth factor alpha. (192 aa) |
| | PROP1 | PROP paired-like homeobox 1. (226 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | CRHR1 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (426 aa) |
| | XBP1 | X-box binding protein 1. (383 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | WT1 | WT1 transcription factor. (523 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (857 aa) |
| | HAND2 | Heart and neural crest derivatives expressed 2. (275 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (264 aa) |
| | EDA | Ectodysplasin A; Belongs to the tumor necrosis factor family. (388 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa) |
| | CCKBR | Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (454 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1500 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa) |
| | NKX2-3 | NK2 homeobox 3. (368 aa) |
| | PLAG1 | PLAG1 zinc finger. (499 aa) |
| | PTCH1 | Patched 1. (1451 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa) |
| | SOX9 | SRY-box transcription factor 9. (511 aa) |
| | HOXA3 | Homeobox A3. (441 aa) |
| | FEM1B | Fem-1 homolog B. (627 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | NPHP3 | TPR_REGION domain-containing protein. (1348 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (620 aa) |
| | LHX3 | LIM homeobox 3. (403 aa) |
| | FGL1 | Fibrinogen like 1. (378 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (555 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (415 aa) |
| | MSX1 | Msh homeobox 1. (303 aa) |
| | TBX3 | T-box transcription factor 3. (745 aa) |
| | NR5A1 | Nuclear receptor subfamily 5 group A member 1. (461 aa) |
| | EDAR | Ectodysplasin A receptor. (447 aa) |
| | DAG1 | Peptidase S72 domain-containing protein. (892 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | HOXA5 | Homeobox A5. (381 aa) |
| | BCL2L11 | Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa) |
| | LOC101093046 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (208 aa) |
| | CEBPG | BZIP domain-containing protein. (465 aa) |
| | HOXA9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (272 aa) |
| | PITX1 | Homeobox protein. (313 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) |
| | RARG | Retinoic acid receptor gamma. (459 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | GDF7 | Growth differentiation factor 7. (455 aa) |
| | HOXA13 | Homeobox A13. (389 aa) |
| | ZIC3 | Zic family member 3. (553 aa) |
| | CADM1 | Cell adhesion molecule 1. (593 aa) |
| | SIX4 | SIX homeobox 4. (784 aa) |
| | NKX3-1 | NK3 homeobox 1. (231 aa) |
| | USF2 | Upstream transcription factor 2, c-fos interacting. (367 aa) |
| | SEC63 | SEC63 homolog, protein translocation regulator. (793 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1251 aa) |
| | SLC46A2 | Solute carrier family 46 member 2. (500 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (428 aa) |
| | NFIB | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | NF1 | Neurofibromin 1. (2856 aa) |
| | TGM2 | Transglutaminase 2. (733 aa) |
| | PTCD2 | Pentatricopeptide repeat domain 2. (388 aa) |
| | RPGRIP1L | RPGRIP1 like. (1392 aa) |
| | ASCL1 | Achaete-scute family bHLH transcription factor 1. (246 aa) |
| | ENSFCAP00000057780 | Uncharacterized protein. (585 aa) |
| | ADA | Adenosine deaminase. (431 aa) |
| | ENSFCAP00000057918 | Uncharacterized protein. (293 aa) |
| | ELK1 | ETS transcription factor ELK1. (487 aa) |
| | PKD1 | Polycystin 1, transient receptor potential channel interacting. (4299 aa) |
| | SULF2 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. (893 aa) |
| | NTN1 | Netrin 1. (715 aa) |
| | ETV4 | ETS variant 4. (488 aa) |
| | MKI67 | FHA domain-containing protein. (2865 aa) |
| | ARF6 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (140 aa) |
| | TNFRSF11A | TNF receptor superfamily member 11a. (638 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1382 aa) |
| | ANXA1 | Annexin. (407 aa) |
| | OTP | Orthopedia homeobox. (415 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (467 aa) |
