19 items (Felis catus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NF1	Neurofibromin 1. (2856 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa)
	ENG	Endoglin. (654 aa)
	TIPARP	TCDD inducible poly(ADP-ribose) polymerase. (692 aa)
	COL3A1	Collagen type III alpha 1 chain. (1466 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
	SRF	Serum response factor. (512 aa)
	OSR1	Odd-skipped related transcription factor 1. (267 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (970 aa)
	STRA6	Stimulated by retinoic acid 6. (700 aa)
	LOC101094201	SCHIP-1 domain-containing protein. (489 aa)
	ZFAND5	Zinc finger AN1-type containing 5. (213 aa)
	PTCH1	Patched 1. (1451 aa)
	SOX9	SRY-box transcription factor 9. (511 aa)
	DLG2	Discs large MAGUK scaffold protein 2. (1012 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	IHH	ENSFCAP00000051185	ENSFCAP00000017498	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.585
BMP4	PTCH1	ENSFCAP00000051185	ENSFCAP00000044951	Bone morphogenetic protein 4.	Patched 1.	0.526
BMP4	SHH	ENSFCAP00000051185	ENSFCAP00000061011	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.783
BMP4	SOX9	ENSFCAP00000051185	ENSFCAP00000045943	Bone morphogenetic protein 4.	SRY-box transcription factor 9.	0.625
DLG1	DLG2	ENSFCAP00000050965	ENSFCAP00000048751	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	Discs large MAGUK scaffold protein 2.	0.901
DLG2	DLG1	ENSFCAP00000048751	ENSFCAP00000050965	Discs large MAGUK scaffold protein 2.	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family.	0.901
IHH	BMP4	ENSFCAP00000017498	ENSFCAP00000051185	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.585
IHH	PTCH1	ENSFCAP00000017498	ENSFCAP00000044951	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 1.	0.988
IHH	SHH	ENSFCAP00000017498	ENSFCAP00000061011	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.906
IHH	SMO	ENSFCAP00000017498	ENSFCAP00000059936	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.797
IHH	SOX9	ENSFCAP00000017498	ENSFCAP00000045943	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	SRY-box transcription factor 9.	0.607
LOC101094201	TIPARP	ENSFCAP00000041749	ENSFCAP00000012349	SCHIP-1 domain-containing protein.	TCDD inducible poly(ADP-ribose) polymerase.	0.594
LOC101094201	ZFAND5	ENSFCAP00000041749	ENSFCAP00000043340	SCHIP-1 domain-containing protein.	Zinc finger AN1-type containing 5.	0.778
PKD2	SMO	ENSFCAP00000025910	ENSFCAP00000059936	Polycystin 2, transient receptor potential cation channel.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.560
PTCH1	BMP4	ENSFCAP00000044951	ENSFCAP00000051185	Patched 1.	Bone morphogenetic protein 4.	0.526
PTCH1	IHH	ENSFCAP00000044951	ENSFCAP00000017498	Patched 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.988
PTCH1	SHH	ENSFCAP00000044951	ENSFCAP00000061011	Patched 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.991
PTCH1	SMO	ENSFCAP00000044951	ENSFCAP00000059936	Patched 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.999
PTCH1	SOX9	ENSFCAP00000044951	ENSFCAP00000045943	Patched 1.	SRY-box transcription factor 9.	0.414
SHH	BMP4	ENSFCAP00000061011	ENSFCAP00000051185	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Bone morphogenetic protein 4.	0.783