STRINGSTRING
RCN3 RCN3 ADCY6 ADCY6 RHO RHO TNS2 TNS2 CRB1 CRB1 LPCAT1 LPCAT1 PASK PASK ALOX12 ALOX12 PRDM14 PRDM14 CDHR1 CDHR1 PNPLA1 PNPLA1 IL20RB IL20RB KLHL10 KLHL10 STAT3 STAT3 RAB3D RAB3D CNGB1 CNGB1 FMO3 FMO3 CCDC66 CCDC66 F2R F2R PBLD PBLD SLC11A2 SLC11A2 SH3GL2 SH3GL2 CRB2 CRB2 SCNN1G SCNN1G SCNN1B SCNN1B FH FH ACCS ACCS SASH3 SASH3 IL1B IL1B TNFSF11 TNFSF11 NOX3 NOX3 NPHP4 NPHP4 KIAA1211 KIAA1211 PM20D1 PM20D1 CYTL1 CYTL1 MRAP2 MRAP2 TJP3 TJP3 POC1B POC1B SLC35D3 SLC35D3 TRPV1 TRPV1 ADRB2 ADRB2 IL1A IL1A ACACB ACACB LOC101086441 LOC101086441 NOD2 NOD2 MKKS MKKS BBS2 BBS2 ILDR1 ILDR1 ALDH1A1 ALDH1A1 TRPM2 TRPM2 ABCA12 ABCA12 AQP6 AQP6 HNF1A HNF1A KDR KDR C1QTNF9 C1QTNF9 LDB2 LDB2 CROCC CROCC CLRN1 CLRN1 ADRB3 ADRB3 CSF1 CSF1 GATA1 GATA1 PIWIL4 PIWIL4 BTBD9 BTBD9 MTF1 MTF1 STK39 STK39 LRRC45 LRRC45 TMEM79 TMEM79 SLC39A8 SLC39A8 XIAP XIAP MKS1 MKS1 ADGRV1 ADGRV1 P2RX7 P2RX7 FMO4 FMO4 TFF1 TFF1 ATP6V1B1 ATP6V1B1 EPAS1 EPAS1 STK11 STK11 NCDN NCDN TFAP2E TFAP2E COL2A1 COL2A1 EDN2 EDN2 SQSTM1 SQSTM1 COL3A1 COL3A1 PROM1 PROM1 MUC13 MUC13 FA2H FA2H ALOX12B ALOX12B ALOXE3 ALOXE3 BPIFA1 BPIFA1 RRP8 RRP8 TPP1 TPP1 TFAP2B TFAP2B ABCA4 ABCA4 BAP1 BAP1 HOMER1 HOMER1 KRAS KRAS GRHL3 GRHL3 ARRDC3 ARRDC3 TFF3 TFF3 KDF1 KDF1 TRIM32 TRIM32 AQP7 AQP7 PRCP PRCP AIPL1 AIPL1 PTK2B PTK2B HOMER2 HOMER2 CLDN5 CLDN5 SRF SRF NOTCH1 NOTCH1 NXNL1 NXNL1 IAPP IAPP UGCG UGCG CDH23 CDH23 CRTC3 CRTC3 STARD7 STARD7 TLR4 TLR4 SFTPD SFTPD IQCB1 IQCB1 NR1D2 NR1D2 ADD1 ADD1 GPR55 GPR55 RB1 RB1 BMP6 BMP6 ERCC6 ERCC6 NOX4 NOX4 NDN NDN CCDC154 CCDC154 IL18 IL18 DRAM2 DRAM2 TJP1 TJP1 SIRT1 SIRT1 EGR1 EGR1 TP63 TP63 USH2A USH2A PRLH PRLH PTH1R PTH1R AQP1 AQP1 OMA1 OMA1 CDH3 CDH3 PTPN11 PTPN11 AQP3 AQP3 MEX3C MEX3C IRX3 IRX3 MBL2 MBL2 MFSD2A MFSD2A LSR LSR IL7 IL7 HAS2 HAS2 BBS4 BBS4 IL17A IL17A CLDN1 CLDN1 SGIP1 SGIP1 FMO2 FMO2 CLCN3 CLCN3 SCNN1A SCNN1A ACACA ACACA WWTR1 WWTR1 AKAP11 AKAP11 PIK3CA PIK3CA RP1 RP1 MAK MAK CORO1A CORO1A LIPA LIPA TLR9 TLR9 VPS54 VPS54 TCIRG1 TCIRG1 LOC111559084 LOC111559084 LRRK1 LRRK1 LEPR LEPR TP53INP2 TP53INP2 ACP5 ACP5 TJP2 TJP2 SRC SRC CFTR CFTR CD7 CD7 ADRB1 ADRB1 PTH PTH LDB1 LDB1 FLCN FLCN TMPRSS11F TMPRSS11F TSKU TSKU ALK ALK EXT1 EXT1 ANKRD12 ANKRD12 CXADR CXADR CYP26B1 CYP26B1 USH1C USH1C ELOVL1 ELOVL1 WHRN WHRN SOX9 SOX9 NKIRAS2 NKIRAS2 NPHP3 NPHP3 ENSFCAP00000046616 ENSFCAP00000046616 TUB TUB ACER1 ACER1 ILDR2 ILDR2 FMO1 FMO1 ENSFCAP00000047497 ENSFCAP00000047497 TRAF6 TRAF6 ACADVL ACADVL LOC101081130 LOC101081130 AQP4 AQP4 WFS1 WFS1 TULP1 TULP1 VSIG1 VSIG1 YAP1 YAP1 SNX10 SNX10 STRAP STRAP HOXA13 HOXA13 ADGRF5 ADGRF5 NR1D1 NR1D1 MLLT6 MLLT6 NAPEPLD NAPEPLD PPP1R13L PPP1R13L TRPV4 TRPV4 NANOS1 NANOS1 CCN2 CCN2 COMP COMP PPARGC1A PPARGC1A VSTM4 VSTM4 USH1G USH1G SPATA7 SPATA7 ENSFCAP00000057142 ENSFCAP00000057142 NKIRAS1 NKIRAS1 HRNR HRNR USP45 USP45 ATP1B2 ATP1B2 CTSH CTSH NAPSA NAPSA DLL1 DLL1 TNFRSF11A TNFRSF11A CROCC2 CROCC2 CRTC1 CRTC1 SMO SMO BBS1 BBS1 MET MET SFN SFN CD34 CD34 TFF2 TFF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RCN3Reticulocalbin 3. (328 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1208 aa)
RHORhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa)
TNS2Tensin 2. (1409 aa)
CRB1Crumbs cell polarity complex component 1. (1405 aa)
LPCAT1Lysophosphatidylcholine acyltransferase 1. (533 aa)
PASKPAS domain containing serine/threonine kinase. (1505 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (664 aa)
PRDM14PR/SET domain 14. (572 aa)
CDHR1Cadherin related family member 1. (859 aa)
PNPLA1Patatin like phospholipase domain containing 1. (571 aa)
IL20RBInterleukin 20 receptor subunit beta. (294 aa)
KLHL10Kelch like family member 10. (608 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
RAB3DRAB3D, member RAS oncogene family. (219 aa)
CNGB1Cyclic nucleotide-binding domain-containing protein. (1204 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
CCDC66Coiled-coil domain containing 66. (961 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
SLC11A2Solute carrier family 11 member 2. (656 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
CRB2Crumbs cell polarity complex component 2. (1283 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (763 aa)
FHFumarate hydratase. (518 aa)
ACCSExostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (863 aa)
SASH3SAM and SH3 domain containing 3. (379 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
NOX3NADPH oxidase 3. (567 aa)
NPHP4Nephrocystin 4. (1425 aa)
KIAA1211KIAA1211. (1329 aa)
PM20D1Peptidase M20 domain containing 1. (503 aa)
CYTL1Cytokine like 1. (135 aa)
MRAP2Melanocortin 2 receptor accessory protein 2. (212 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (910 aa)
POC1BPOC1 centriolar protein B. (478 aa)
SLC35D3Solute carrier family 35 member D3. (422 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (841 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
IL1AInterleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (270 aa)
ACACBAcetyl-CoA carboxylase beta. (2447 aa)
LOC101086441Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1014 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (720 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (545 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1500 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
AQP6Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (283 aa)
HNF1AHNF1 homeobox A. (639 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1514 aa)
C1QTNF9Adiponectin F1. (332 aa)
LDB2LIM domain binding 2. (373 aa)
CROCCCiliary rootlet coiled-coil, rootletin. (2018 aa)
CLRN1Uncharacterized protein. (232 aa)
ADRB3Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis (By similarity). (398 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (569 aa)
GATA1GATA binding protein 1. (413 aa)
PIWIL4Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. (844 aa)
BTBD9BTB domain containing 9. (612 aa)
MTF1Metal regulatory transcription factor 1. (745 aa)
STK39Serine/threonine kinase 39. (543 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
TMEM79Transmembrane protein 79. (394 aa)
SLC39A8Solute carrier family 39 member 8. (461 aa)
XIAPX-linked inhibitor of apoptosis. (454 aa)
MKS1MKS transition zone complex subunit 1. (627 aa)
ADGRV1Adhesion G protein-coupled receptor V1. (6309 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (565 aa)
TFF1Trefoil factor family peptide 1. (81 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
EPAS1Endothelial PAS domain protein 1. (872 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa)
NCDNNeurochondrin. (732 aa)
TFAP2ETranscription factor AP-2 epsilon. (441 aa)
COL2A1Collagen type II alpha 1 chain. (1486 aa)
EDN2Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (178 aa)
SQSTM1Sequestosome 1. (443 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
PROM1Prominin 1. (855 aa)
MUC13Mucin 13, cell surface associated. (603 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (699 aa)
ALOXE3Arachidonate lipoxygenase 3. (711 aa)
BPIFA1BPI fold containing family A member 1. (255 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (509 aa)
TPP1Tripeptidyl peptidase 1. (562 aa)
TFAP2BTranscription factor AP-2 beta. (476 aa)
ABCA4ATP binding cassette subfamily A member 4. (2267 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
HOMER1Homer scaffold protein 1. (354 aa)
KRASUncharacterized protein. (380 aa)
GRHL3Grainyhead like transcription factor 3. (602 aa)
ARRDC3Arrestin domain containing 3. (414 aa)
TFF3Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity). (80 aa)
KDF1Keratinocyte differentiation factor 1. (397 aa)
TRIM32Uncharacterized protein. (669 aa)
AQP7Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (350 aa)
PRCPProlylcarboxypeptidase. (548 aa)
AIPL1Aryl hydrocarbon receptor interacting protein-like 1. (328 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
HOMER2Homer scaffold protein 2. (354 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
SRFSerum response factor. (512 aa)
NOTCH1Notch receptor 1. (2543 aa)
NXNL1Nucleoredoxin like 1. (212 aa)
IAPPIslet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family. (89 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
CDH23Cadherin related 23. (3354 aa)
CRTC3CREB regulated transcription coactivator 3. (618 aa)
STARD7StAR related lipid transfer domain containing 7. (407 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (870 aa)
SFTPDSurfactant protein D. (458 aa)
IQCB1IQ motif containing B1. (598 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (576 aa)
ADD1Adducin 1. (761 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (320 aa)
RB1RB transcriptional corepressor 1. (930 aa)
BMP6Bone morphogenetic protein 6. (502 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1484 aa)
NOX4NADPH oxidase 4. (578 aa)
NDNNecdin, MAGE family member. (324 aa)
CCDC154Coiled-coil domain containing 154. (524 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa)
DRAM2DNA damage regulated autophagy modulator 2. (275 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (2008 aa)
SIRT1Sirtuin 1. (745 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
USH2AUsherin. (5203 aa)
PRLHProlactin releasing hormone. (83 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (590 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (310 aa)
OMA1OMA1 zinc metallopeptidase. (527 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (831 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
MEX3CMex-3 RNA binding family member C. (657 aa)
IRX3Iroquois homeobox 3. (502 aa)
MBL2C-type lectin domain-containing protein. (243 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (529 aa)
LSRLipolysis stimulated lipoprotein receptor. (647 aa)
IL7Interleukin 7. (158 aa)
HAS2Hyaluronan synthase 2. (552 aa)
BBS4Bardet-Biedl syndrome 4. (525 aa)
IL17AInterleukin 17A. (155 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (853 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (537 aa)
CLCN3Chloride channel protein. (866 aa)
SCNN1AUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (645 aa)
ACACAAcetyl-CoA carboxylase alpha. (2385 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
AKAP11A-kinase anchoring protein 11. (1908 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RP1RP1 axonemal microtubule associated. (2137 aa)
MAKMale germ cell associated kinase. (656 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (655 aa)
LIPALipase A, lysosomal acid type. (491 aa)
TLR9Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa)
VPS54VPS54 subunit of GARP complex. (977 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (954 aa)
LOC111559084Peptidase S53 domain-containing protein. (572 aa)
LRRK1Leucine rich repeat kinase 1. (2188 aa)
LEPRLeptin receptor. (1166 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (221 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1180 aa)
SRCTyrosine-protein kinase. (678 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
CD7Ig-like domain-containing protein. (276 aa)
ADRB1Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity). (474 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D- glucose (2DG) transport and glycogen synthesis in osteoblastic cells (By similarity). (115 aa)
LDB1LIM domain binding 1. (411 aa)
FLCNUncharacterized protein. (579 aa)
TMPRSS11FTransmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)
TSKUTsukushi, small leucine rich proteoglycan. (390 aa)
ALKTyrosine-protein kinase receptor. (1279 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ANKRD12Ankyrin repeat domain 12. (2060 aa)
CXADRUncharacterized protein. (352 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
USH1CUSH1 protein network component harmonin. (899 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (287 aa)
WHRNWhirlin. (918 aa)
SOX9SRY-box transcription factor 9. (511 aa)
NKIRAS2Uncharacterized protein. (41 aa)
NPHP3TPR_REGION domain-containing protein. (1348 aa)
ENSFCAP00000046616Uncharacterized protein. (1938 aa)
TUBTubby-like protein; Belongs to the TUB family. (560 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (644 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
ENSFCAP00000047497Nanos-type domain-containing protein; Belongs to the nanos family. (272 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
LOC101081130AIG1-type G domain-containing protein. (309 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
WFS1Wolframin ER transmembrane glycoprotein. (888 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (545 aa)
VSIG1V-set and immunoglobulin domain containing 1. (423 aa)
YAP1Yes associated protein 1. (498 aa)
SNX10Sorting nexin 10. (201 aa)
STRAPWD_REPEATS_REGION domain-containing protein. (350 aa)
HOXA13Homeobox A13. (389 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1387 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (625 aa)
MLLT6MLLT6, PHD finger containing. (1198 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (394 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (867 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (963 aa)
NANOS1Nanos-type domain-containing protein; Belongs to the nanos family. (352 aa)
CCN2Cellular communication network factor 2. (477 aa)
COMPCartilage oligomeric matrix protein. (804 aa)
PPARGC1APPARG coactivator 1 alpha. (803 aa)
VSTM4V-set and transmembrane domain containing 4. (389 aa)
USH1GUSH1 protein network component sans. (670 aa)
SPATA7Spermatogenesis associated 7. (600 aa)
ENSFCAP00000057142Uncharacterized protein. (773 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (289 aa)
HRNREF-hand domain-containing protein. (840 aa)
USP45Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (813 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (306 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (572 aa)
NAPSANapsin A aspartic peptidase; Belongs to the peptidase A1 family. (432 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (731 aa)
TNFRSF11ATNF receptor superfamily member 11a. (638 aa)
CROCC2Ciliary rootlet coiled-coil, rootletin family member 2. (1572 aa)
CRTC1CREB regulated transcription coactivator 1. (654 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa)
BBS1BBS1 domain-containing protein. (602 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1382 aa)
SFNStratifin; Belongs to the 14-3-3 family. (252 aa)
CD34CD34 molecule. (406 aa)
TFF2Trefoil factor 2. (176 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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