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MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2590 aa) | ||||
PLXND1 | Plexin D1. (1927 aa) | ||||
LOC101097531 | Uncharacterized protein; Belongs to the parvalbumin family. (109 aa) | ||||
CHCHD6 | MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (2112 aa) | ||||
CDKL5 | Cyclin dependent kinase like 5. (978 aa) | ||||
SNW1 | SNW domain containing 1. (570 aa) | ||||
PLXNB1 | Plexin B1. (2135 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (421 aa) | ||||
ANKRD27 | Ankyrin repeat domain 27. (1050 aa) | ||||
SLITRK1 | SLIT and NTRK like family member 1. (696 aa) | ||||
SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (484 aa) | ||||
CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (399 aa) | ||||
STK25 | Serine/threonine kinase 25. (426 aa) | ||||
SOX10 | SRY-box transcription factor 10. (604 aa) | ||||
POU4F2 | POU domain protein. (408 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (825 aa) | ||||
CTNNB1 | Catenin beta 1. (783 aa) | ||||
TNFRSF1B | TNF receptor superfamily member 1B. (463 aa) | ||||
SEMA4D | Semaphorin 4D; Belongs to the semaphorin family. (863 aa) | ||||
NUMBL | NUMB like endocytic adaptor protein. (678 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (472 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) | ||||
LRP2 | LDL receptor related protein 2. (4646 aa) | ||||
TIAM2 | T cell lymphoma invasion and metastasis 2. (1694 aa) | ||||
SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (417 aa) | ||||
NPTN | Neuroplastin. (446 aa) | ||||
ELL3 | Elongation factor for RNA polymerase II 3. (395 aa) | ||||
SRRT | Serrate, RNA effector molecule. (876 aa) | ||||
XRCC2 | X-ray repair cross complementing 2. (276 aa) | ||||
PAX6 | Paired box 6. (437 aa) | ||||
UFL1 | UFM1 specific ligase 1. (792 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) | ||||
SEMA7A | Semaphorin 7A; Belongs to the semaphorin family. (769 aa) | ||||
EGR2 | Early growth response 2. (541 aa) | ||||
TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (766 aa) | ||||
LPAR3 | Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (383 aa) | ||||
RNF112 | Ring finger protein 112. (629 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) | ||||
FN1 | Fibronectin 1. (2475 aa) | ||||
MAN2A1 | Alpha-mannosidase. (1145 aa) | ||||
CUL7 | Cullin 7; Belongs to the cullin family. (1695 aa) | ||||
IL6ST | Interleukin 6 signal transducer. (918 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
PLXNB2 | Plexin B2. (1841 aa) | ||||
GLI3 | GLI family zinc finger 3. (1578 aa) | ||||
BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) | ||||
PRKCH | Protein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa) | ||||
STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (439 aa) | ||||
KDM1A | Lysine demethylase 1A. (944 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) | ||||
SS18L1 | SS18L1 subunit of BAF chromatin remodeling complex. (402 aa) | ||||
KRAS | Uncharacterized protein. (380 aa) | ||||
CLCF1 | Cardiotrophin like cytokine factor 1. (340 aa) | ||||
TRIM32 | Uncharacterized protein. (669 aa) | ||||
NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (574 aa) | ||||
TWF2 | Twinfilin actin binding protein 2. (349 aa) | ||||
SRF | Serum response factor. (512 aa) | ||||
NOTCH1 | Notch receptor 1. (2543 aa) | ||||
SHTN1 | Shootin 1. (631 aa) | ||||
ISLR | Immunoglobulin superfamily containing leucine rich repeat. (428 aa) | ||||
ASPA | Aspartoacylase. (313 aa) | ||||
PKHD1L1 | PKHD1 like 1. (4242 aa) | ||||
DBN1 | Drebrin 1. (703 aa) | ||||
CAPRIN1 | Cell cycle associated protein 1. (709 aa) | ||||
FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) | ||||
GSX2 | GS homeobox 2. (305 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa) | ||||
PTN | Pleiotrophin. (179 aa) | ||||
ASPM | Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity). (3478 aa) | ||||
MAP6 | Microtubule associated protein 6. (770 aa) | ||||
BHLHB9 | Arm_2 domain-containing protein. (550 aa) | ||||
LIG4 | DNA ligase. (911 aa) | ||||
IL34 | Interleukin 34. (331 aa) | ||||
JADE2 | Jade family PHD finger 2. (827 aa) | ||||
NKX6-1 | NK6 homeobox 1. (367 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) | ||||
METRNL | Meteorin like, glial cell differentiation regulator. (310 aa) | ||||
CDKL3 | Cyclin dependent kinase like 3. (581 aa) | ||||
NIN | Ninein. (2128 aa) | ||||
METRN | Meteorin, glial cell differentiation regulator. (434 aa) | ||||
PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa) | ||||
OPRM1 | Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (419 aa) | ||||
OLIG2 | BHLH domain-containing protein. (519 aa) | ||||
DISC1 | DISC1 scaffold protein. (877 aa) | ||||
WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) | ||||
DCT | Dopachrome tautomerase. (664 aa) | ||||
IST1 | IST1 factor associated with ESCRT-III. (366 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (395 aa) | ||||
ISLR2 | Immunoglobulin superfamily containing leucine rich repeat 2. (855 aa) | ||||
ITGB1 | Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa) | ||||
PLXNC1 | Plexin C1. (1576 aa) | ||||
LIF | LIF interleukin 6 family cytokine. (204 aa) | ||||
LIMK1 | LIM domain kinase 1. (763 aa) | ||||
WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) | ||||
PLXNA2 | Plexin A2. (1911 aa) | ||||
BIN1 | Bridging integrator 1. (608 aa) | ||||
SOX8 | SRY-box 8. (883 aa) | ||||
MARCKS | Myristoylated alanine rich protein kinase C substrate. (353 aa) | ||||
CAPRIN2 | Caprin family member 2. (1019 aa) | ||||
LRP8 | LDL receptor related protein 8. (1015 aa) | ||||
FAIM | Fas apoptotic inhibitory molecule. (201 aa) | ||||
EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) | ||||
ZNF365 | Zinc finger protein 365. (407 aa) | ||||
OBSL1 | Obscurin like 1. (2117 aa) | ||||
MEGF8 | Multiple EGF like domains 8. (2789 aa) | ||||
ZFYVE27 | Zinc finger FYVE-type containing 27. (420 aa) | ||||
GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa) | ||||
DMRTA2 | DMRT like family A2. (535 aa) | ||||
PLAG1 | PLAG1 zinc finger. (499 aa) | ||||
NGF | Nerve growth factor; Belongs to the NGF-beta family. (259 aa) | ||||
TENM4 | Teneurin transmembrane protein 4. (2823 aa) | ||||
CHODL | Chondrolectin. (272 aa) | ||||
DHX36 | DEAH-box helicase 36. (1012 aa) | ||||
LAYN | Layilin. (380 aa) | ||||
NEFL | Neurofilament light; Belongs to the intermediate filament family. (543 aa) | ||||
MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa) | ||||
BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (255 aa) | ||||
NKX6-2 | NK6 homeobox 2. (285 aa) | ||||
FOXG1 | Forkhead box G1. (483 aa) | ||||
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (483 aa) | ||||
NUMB | NUMB endocytic adaptor protein. (653 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa) | ||||
HES1 | Hes family bHLH transcription factor 1. (280 aa) | ||||
PLXNA4 | Plexin A4. (1893 aa) | ||||
CUX2 | Homeobox protein cut-like. (1499 aa) | ||||
MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (1021 aa) | ||||
XRCC5 | X-ray repair cross complementing 5. (747 aa) | ||||
GOLGA4 | Golgin A4. (2306 aa) | ||||
PLXNB3 | Plexin B3. (2058 aa) | ||||
FBXW8 | F-box and WD repeat domain containing 8. (701 aa) | ||||
TGM2 | Transglutaminase 2. (733 aa) | ||||
ENSFCAP00000056200 | MOEP19 domain-containing protein. (399 aa) | ||||
ASCL1 | Achaete-scute family bHLH transcription factor 1. (246 aa) | ||||
RELN | Reelin. (3460 aa) | ||||
NTN1 | Netrin 1. (715 aa) | ||||
ZNF335 | Zinc finger protein 335. (1446 aa) | ||||
SPEN | Spen family transcriptional repressor. (3678 aa) | ||||
SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (795 aa) | ||||
DBNL | Drebrin like. (522 aa) | ||||
ZNF488 | Zinc finger protein 488. (233 aa) | ||||
PLXNA3 | Plexin A3. (1872 aa) | ||||
OTP | Orthopedia homeobox. (415 aa) |