STRINGSTRING
PTEN PTEN LRRC4C LRRC4C GRM3 GRM3 CPLX3 CPLX3 BCR BCR CHRM2 CHRM2 M3WTU8_FELCA M3WTU8_FELCA KIF5B KIF5B FRRS1L FRRS1L SYAP1 SYAP1 NEURL1 NEURL1 CFAP299 CFAP299 CACNG2 CACNG2 CACNG8 CACNG8 SRF SRF NLGN2 NLGN2 LRRTM1 LRRTM1 SHISA8 SHISA8 TMEM108 TMEM108 AKAP5 AKAP5 SYT1 SYT1 CDK5 CDK5 CACNG5 CACNG5 DBN1 DBN1 RAP1A RAP1A ADORA2A ADORA2A PCDH17 PCDH17 PTN PTN RASGRF2 RASGRF2 PHF24 PHF24 ITPKA ITPKA SLC8A2 SLC8A2 DGKE DGKE ATP2A2 ATP2A2 NSMF NSMF RAP1B RAP1B MAPK1 MAPK1 LZTS1 LZTS1 KCTD13 KCTD13 SLC24A1 SLC24A1 ENSFCAP00000026456 ENSFCAP00000026456 IGSF11 IGSF11 YWHAG YWHAG PLCL1 PLCL1 CACNG4 CACNG4 GRM2 GRM2 CASK CASK SNAP25 SNAP25 DGKB DGKB STXBP5 STXBP5 CLN3 CLN3 GIT1 GIT1 NLGN3 NLGN3 MEF2C MEF2C GIPC2 GIPC2 BDKRB2 BDKRB2 ITGB1 ITGB1 GRM8 GRM8 EPHB2 EPHB2 UNC13C UNC13C CDC20 CDC20 DRD5 DRD5 CACNB4 CACNB4 PRKAR2B PRKAR2B CSPG5 CSPG5 STXBP5L STXBP5L SNAP47 SNAP47 ARC ARC VGF VGF GRIA1 GRIA1 PPP1R9A PPP1R9A PRKCE PRKCE LRFN2 LRFN2 CNRIP1 CNRIP1 PRRT2 PRRT2 S100B S100B DLG4 DLG4 PPP3CA PPP3CA NRG3 NRG3 CPLX2 CPLX2 PTPRA PTPRA RAB3A RAB3A SNCAIP SNCAIP LGI1 LGI1 NLGN4X NLGN4X PAIP2 PAIP2 TPRG1 TPRG1 GRIK2 GRIK2 MPP2 MPP2 LRP8 LRP8 NTNG2 NTNG2 CACNB2 CACNB2 CACNA1A CACNA1A FBXL20 FBXL20 ERC1 ERC1 CHRDL1 CHRDL1 CDC20B CDC20B EPHB1 EPHB1 MCTP1 MCTP1 RASGRF1 RASGRF1 CPLX1 CPLX1 ENSFCAP00000054808 ENSFCAP00000054808 CLSTN1 CLSTN1 EIF4EBP2 EIF4EBP2 PLCG1 PLCG1 NPS NPS PLCB4 PLCB4 NF1 NF1 ADCY1 ADCY1 DLGAP1 DLGAP1 SORCS2 SORCS2 RELN RELN GRIN2C GRIN2C CBLN1 CBLN1 LOC109497044 LOC109497044 DRD3 DRD3 GRIK4 GRIK4 AKAP7 AKAP7 MAPK8IP2 MAPK8IP2 LRRC4 LRRC4 SHISA7 SHISA7 NTNG1 NTNG1 CYP46A1 CYP46A1 APBA1 APBA1 PFN2 PFN2 EIF4E EIF4E GRM4 GRM4 STX1A STX1A PRKN PRKN CALB1 CALB1 BAIAP2 BAIAP2 GSK3B GSK3B GPER1 GPER1 SYT2 SYT2 PTPRS PTPRS PACSIN2 PACSIN2 GRIN2B GRIN2B PRRT1 PRRT1 GRM5 GRM5 NGF NGF BEGAIN BEGAIN NCSTN NCSTN RIMS2 RIMS2 SYNPR SYNPR RIMS1 RIMS1 GRID2 GRID2 MECP2 MECP2 BDNF BDNF SYNGAP1 SYNGAP1 NFATC4 NFATC4 GRM7 GRM7 MCTP2 MCTP2 SCT SCT UCN UCN STXBP1 STXBP1 VPS18 VPS18 SYNGR1 SYNGR1 ACTN1 ACTN1 DNM1 DNM1 NPTXR NPTXR CACNA1B CACNA1B SLC24A2 SLC24A2 HOMER3 HOMER3 PPP1R9B PPP1R9B AKAP12 AKAP12 DRD4 DRD4 IQSEC2 IQSEC2 TNF TNF DLGAP2 DLGAP2 DGKZ DGKZ OPHN1 OPHN1 ENSFCAP00000051698 ENSFCAP00000051698 RIMS3 RIMS3 CUX2 CUX2 PNKD PNKD RGS14 RGS14 STX3 STX3 DGKI DGKI CDH11 CDH11 NOG NOG CRHR2 CRHR2 PXK PXK RAB5A RAB5A KCNJ10 KCNJ10 BACE1 BACE1 CLSTN3 CLSTN3 NTF4 NTF4 PREPL PREPL PINK1 PINK1 CCL2 CCL2 APP APP CACNG7 CACNG7 LRRK2 LRRK2 RNF19A RNF19A CHRNA5 CHRNA5 KAT2A KAT2A NR2E1 NR2E1 ZZEF1 ZZEF1 CLSTN2 CLSTN2 RAPSN RAPSN STX1B STX1B NRGN NRGN SERPINE2 SERPINE2 CX3CR1 CX3CR1 PICK1 PICK1 SLC7A11 SLC7A11 SYP SYP NPTX2 NPTX2 SLC4A8 SLC4A8 SLC4A10 SLC4A10 AGER AGER P2RX3 P2RX3 ABL1 ABL1 GRIK3 GRIK3 NALCN NALCN GFAP GFAP SLC1A3 SLC1A3 ZDHHC12 ZDHHC12 NPTN NPTN ADCY8 ADCY8 ABHD6 ABHD6 CNTN2 CNTN2 NTF3 NTF3 GIPC3 GIPC3 DMPK DMPK SYT12 SYT12 SORCS3 SORCS3 DVL1 DVL1 FLOT1 FLOT1 EPHA4 EPHA4 LGMN LGMN ADRB2 ADRB2 SNAPIN SNAPIN JPH3 JPH3 GRIK1 GRIK1 NLGN1 NLGN1 NTRK2 NTRK2 ATF4 ATF4 NPAS4 NPAS4 KCNB1 KCNB1 GRM6 GRM6 CALB2 CALB2 ERC2 ERC2 ANAPC2 ANAPC2 GRM1 GRM1 BTBD9 BTBD9 GRID1 GRID1 CACNG3 CACNG3 DTNBP1 DTNBP1 PRKCB PRKCB TPRG1L TPRG1L TMEM25 TMEM25 SHISA6 SHISA6 P2RX7 P2RX7 GRIK5 GRIK5 CA7 CA7 BRAF BRAF DCC DCC DLGAP4 DLGAP4 S1PR2 S1PR2 ATAD1 ATAD1 CYFIP1 CYFIP1 GIPC1 GIPC1 NCDN NCDN ADIPOQ ADIPOQ DLGAP3 DLGAP3 GRIN2A GRIN2A TNR TNR SCGN SCGN SQSTM1 SQSTM1 EDN1 EDN1 NETO1 NETO1 HOMER1 HOMER1 RAB26 RAB26 GRIN3A GRIN3A GRID2IP GRID2IP JPH4 JPH4 GRIN2D GRIN2D KRAS KRAS
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
GRM3Glutamate metabotropic receptor 3. (958 aa)
CPLX3Complexin 3. (183 aa)
BCRBCR activator of RhoGEF and GTPase. (1282 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
M3WTU8_FELCAUncharacterized protein. (84 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
FRRS1LFerric chelate reductase 1 like. (342 aa)
SYAP1Synapse associated protein 1. (358 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
CFAP299Cilia and flagella associated protein 299. (233 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (422 aa)
SRFSerum response factor. (512 aa)
NLGN2Neuroligin 2. (834 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
SHISA8Shisa family member 8. (398 aa)
TMEM108Transmembrane protein 108. (581 aa)
AKAP5A-kinase anchoring protein 5. (428 aa)
SYT1Synaptotagmin 1. (469 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (324 aa)
DBN1Drebrin 1. (703 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
PCDH17Protocadherin 17. (1196 aa)
PTNPleiotrophin. (179 aa)
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1239 aa)
PHF24PHD finger protein 24. (400 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
DGKEDiacylglycerol kinase. (564 aa)
ATP2A2Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytos [...] (1006 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (534 aa)
RAP1BRAP1B, member of RAS oncogene family. (187 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the PP2C family. (698 aa)
LZTS1Leucine zipper tumor suppressor 1. (606 aa)
KCTD13Potassium channel tetramerization domain containing 13. (329 aa)
SLC24A1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1097 aa)
ENSFCAP00000026456Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (128 aa)
IGSF11Immunoglobulin superfamily member 11. (427 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (289 aa)
PLCL1Phosphoinositide phospholipase C. (1040 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (935 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (234 aa)
DGKBDiacylglycerol kinase. (820 aa)
STXBP5Syntaxin binding protein 5. (1179 aa)
CLN3Battenin. (438 aa)
GIT1GIT ArfGAP 1. (770 aa)
NLGN3Neuroligin 3. (781 aa)
MEF2CMADS-box domain-containing protein. (483 aa)
GIPC2GIPC PDZ domain containing family member 2. (313 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (392 aa)
ITGB1Integrin beta-1; Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha- 4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha- 11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha- 4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin [...] (801 aa)
GRM8Glutamate metabotropic receptor 8. (908 aa)
EPHB2EPH receptor B2. (899 aa)
UNC13CUnc-13 homolog C. (2225 aa)
CDC20Cell division cycle 20. (499 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (474 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (519 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (618 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (564 aa)
STXBP5LSyntaxin binding protein 5 like. (1024 aa)
SNAP47Synaptosome associated protein 47. (441 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
VGFVGF nerve growth factor inducible. (616 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (906 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1384 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (792 aa)
CNRIP1Uncharacterized protein. (324 aa)
PRRT2Proline rich transmembrane protein 2. (362 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (797 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
NRG3Neuregulin 3. (720 aa)
CPLX2Complexin 2. (134 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (826 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
SNCAIPSynuclein alpha interacting protein. (1014 aa)
LGI1Leucine-rich glioma-inactivated protein 1. (557 aa)
NLGN4XCOesterase domain-containing protein. (836 aa)
PAIP2Poly(A) binding protein interacting protein 2. (126 aa)
TPRG1Tumor protein p63 regulated 1. (286 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
MPP2Uncharacterized protein; Belongs to the MAGUK family. (569 aa)
LRP8LDL receptor related protein 8. (1015 aa)
NTNG2Netrin G2. (613 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (632 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2498 aa)
FBXL20F-box domain-containing protein. (438 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1149 aa)
CHRDL1Chordin like 1. (602 aa)
CDC20BCell division cycle 20B. (520 aa)
EPHB1EPH receptor B1. (984 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (999 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1312 aa)
CPLX1Complexin 1. (178 aa)
ENSFCAP00000054808Uncharacterized protein. (786 aa)
CLSTN1Calsyntenin 1. (983 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (142 aa)
PLCG1Phosphoinositide phospholipase C. (1391 aa)
NPSNeuropeptide S. (114 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa)
NF1Neurofibromin 1. (2856 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1148 aa)
DLGAP1DLG associated protein 1. (987 aa)
SORCS2Sortilin related VPS10 domain containing receptor 2. (1163 aa)
RELNReelin. (3460 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1325 aa)
CBLN1Cerebellin 1 precursor. (194 aa)
LOC109497044Uncharacterized protein. (271 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
AKAP7A-kinase anchoring protein 7. (418 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (834 aa)
LRRC4Leucine rich repeat containing 4. (633 aa)
SHISA7Shisa family member 7. (697 aa)
NTNG1Netrin G1. (581 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (521 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (831 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
GRM4Glutamate metabotropic receptor 4. (912 aa)
STX1ASyntaxin 1A. (334 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa)
CALB1Calbindin 1. (261 aa)
BAIAP2BAI1 associated protein 2. (548 aa)
GSK3BProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (433 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
SYT2Synaptotagmin 2. (595 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1947 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (525 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1486 aa)
PRRT1Proline rich transmembrane protein 1. (306 aa)
GRM5Glutamate metabotropic receptor 5. (1208 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (259 aa)
BEGAINBrain enriched guanylate kinase associated. (842 aa)
NCSTNNicastrin. (709 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1366 aa)
SYNPRSynaptoporin. (453 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (255 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1345 aa)
NFATC4Nuclear factor of activated T cells 4. (930 aa)
GRM7Glutamate metabotropic receptor 7. (922 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (888 aa)
SCTSecretin. (126 aa)
UCNUrocortin. (126 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (1096 aa)
SYNGR1Synaptogyrin. (255 aa)
ACTN1Actinin alpha 1. (927 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
NPTXRNeuronal pentraxin receptor. (508 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2202 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (663 aa)
HOMER3Uncharacterized protein. (419 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (889 aa)
AKAP12A-kinase anchoring protein 12. (1505 aa)
DRD4G_PROTEIN_RECEP_F1_2 domain-containing protein. (595 aa)
IQSEC2IQ motif and Sec7 domain 2. (1520 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (321 aa)
DLGAP2DLG associated protein 2. (1029 aa)
DGKZDiacylglycerol kinase. (1119 aa)
OPHN1Oligophrenin 1. (823 aa)
ENSFCAP00000051698Uncharacterized protein. (205 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (311 aa)
CUX2Homeobox protein cut-like. (1499 aa)
PNKDPNKD metallo-beta-lactamase domain containing. (385 aa)
RGS14Regulator of G protein signaling 14. (607 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (375 aa)
DGKIDiacylglycerol kinase. (1082 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (437 aa)
PXKPX domain containing serine/threonine kinase like. (577 aa)
RAB5ARAB5A, member RAS oncogene family. (240 aa)
KCNJ10Potassium voltage-gated channel subfamily J member 10. (563 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
CLSTN3Calsyntenin 3. (956 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
PREPLProlyl endopeptidase like. (727 aa)
PINK1PTEN induced kinase 1. (581 aa)
CCL2C-C motif chemokine. (99 aa)
APPAmyloid-beta A4 protein; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those mediated by G(O) an [...] (935 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
RNF19ARBR-type E3 ubiquitin transferase. (838 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (475 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (836 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2956 aa)
CLSTN2Calsyntenin 2. (956 aa)
RAPSNReceptor associated protein of the synapse. (412 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (288 aa)
NRGNNeurogranin. (78 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (484 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (399 aa)
PICK1Protein interacting with PRKCA 1. (417 aa)
SLC7A11Solute carrier family 7 member 11. (503 aa)
SYPSynaptophysin. (371 aa)
NPTX2Neuronal pentraxin 2. (431 aa)
SLC4A8Anion exchange protein. (1096 aa)
SLC4A10Anion exchange protein. (1118 aa)
AGERAdvanced glycosylation end-product specific receptor. (492 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (475 aa)
ABL1Tyrosine-protein kinase. (1150 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
NALCNSodium leak channel, non-selective. (1737 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (472 aa)
SLC1A3Amino acid transporter. (542 aa)
ZDHHC12Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (270 aa)
NPTNNeuroplastin. (446 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
CNTN2Contactin 2. (1103 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
DMPKDM1 protein kinase. (801 aa)
SYT12Synaptotagmin 12. (507 aa)
SORCS3Sortilin related VPS10 domain containing receptor 3. (1222 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
EPHA4EPH receptor A4. (986 aa)
LGMNLegumain. (433 aa)
ADRB2Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity). Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB2 sub-subfamily. (418 aa)
SNAPINSNAP associated protein. (229 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (754 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (949 aa)
NLGN1Neuroligin 1. (823 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
ATF4Activating transcription factor 4. (352 aa)
NPAS4Neuronal PAS domain protein 4. (800 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (857 aa)
GRM6Glutamate metabotropic receptor 6. (878 aa)
CALB2Calbindin 2. (271 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (1031 aa)
GRM1Glutamate metabotropic receptor 1. (1190 aa)
BTBD9BTB domain containing 9. (612 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (1009 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
DTNBP1Dystrobrevin binding protein 1. (336 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
TPRG1LTumor protein p63 regulated 1 like. (271 aa)
TMEM25Transmembrane protein 25. (375 aa)
SHISA6Shisa family member 6. (551 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (593 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
CA7Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family. (264 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
DCCDCC netrin 1 receptor. (1446 aa)
DLGAP4DLG associated protein 4. (992 aa)
S1PR2Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family. (352 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (360 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
GIPC1GIPC PDZ domain containing family member 1. (447 aa)
NCDNNeurochondrin. (732 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (283 aa)
DLGAP3DLG associated protein 3. (979 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
TNRTenascin R. (1358 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (276 aa)
SQSTM1Sequestosome 1. (443 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (201 aa)
NETO1Neuropilin and tolloid like 1. (533 aa)
HOMER1Homer scaffold protein 1. (354 aa)
RAB26RAB26, member RAS oncogene family. (255 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1116 aa)
GRID2IPGrid2 interacting protein. (1211 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1338 aa)
KRASUncharacterized protein. (380 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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