STRINGSTRING
HTR2B HTR2B PTK2B PTK2B ESR1 ESR1 S100A1 S100A1 NUS1 NUS1 PIK3CB PIK3CB SCARB1 SCARB1 TERF2 TERF2 GCH1 GCH1 DHFR DHFR FCER2 FCER2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTR2B5-hydroxytryptamine receptor 2B. (503 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1032 aa)
ESR1Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] (595 aa)
S100A1Protein S100; Belongs to the S-100 family. (94 aa)
NUS1NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
TERF2Telomeric repeat binding factor 2. (542 aa)
GCH1GTP_cyclohydroI domain-containing protein. (450 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (212 aa)
FCER2Fc fragment of IgE receptor II. (290 aa)
Your Current Organism:
Felis catus
NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat
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