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| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | DHPS | Deoxyhypusine synthase. (369 aa) |
| | CCDC88B | Coiled-coil domain containing 88B. (1533 aa) |
| | BTNL2 | Butyrophilin like 2. (487 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (761 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | STAT5B | Signal transducer and activator of transcription. (786 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa) |
| | SOX13 | SRY-box 13. (619 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (347 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (492 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | EGR3 | Early growth response 3. (392 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (379 aa) |
| | IL2RA | Interleukin-2 receptor subunit alpha; Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. (275 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (302 aa) |
| | TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (523 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (161 aa) |
| | MMP14 | Matrix metallopeptidase 14. (582 aa) |
| | BCL6 | BCL6 transcription repressor. (745 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1893 aa) |
| | GAS6 | Growth arrest specific 6. (674 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | IL1A | Interleukin-1 alpha; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). (270 aa) |
| | PAXIP1 | PAX interacting protein 1. (1016 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1014 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) |
| | CD274 | CD274 molecule. (297 aa) |
| | PDCD1LG2 | Programmed cell death 1 ligand 2. (302 aa) |
| | KMT5B | Lysine methyltransferase 5B. (888 aa) |
| | TYK2 | Tyrosine-protein kinase. (1181 aa) |
| | CD80 | B-lymphocyte activation antigen B7-1 (CD80). (292 aa) |
| | LOC101090518 | Ig-like domain-containing protein; Belongs to the MHC class II family. (250 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | TBX21 | T-box transcription factor 21. (535 aa) |
| | NSD2 | Nuclear receptor binding SET domain protein 2. (1350 aa) |
| | IL6ST | Interleukin 6 signal transducer. (918 aa) |
| | ZP4 | Processed zona pellucida sperm-binding protein 4; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP4 may act as a sperm receptor; Belongs to the ZP domain family. ZPB subfamily. (570 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | INPP5D | Inositol polyphosphate-5-phosphatase D. (1181 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1066 aa) |
| | RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | GLI3 | GLI family zinc finger 3. (1578 aa) |
| | IL23A | Interleukin 23 subunit alpha. (196 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (118 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | VSIR | V-set immunoregulatory receptor. (311 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | ZP3 | Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. (435 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1301 aa) |
| | CD6 | CD6 molecule. (678 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa) |
| | MALT1 | MALT1 paracaspase. (848 aa) |
| | SYK | Spleen associated tyrosine kinase. (636 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (422 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28; Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. (255 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (803 aa) |
| | STAT6 | Signal transducer and activator of transcription. (844 aa) |
| | EPHB6 | EPH receptor B6. (1012 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (477 aa) |
| | AKIRIN2 | Akirin 2. (203 aa) |
| | RASAL3 | RAS protein activator like 3. (1012 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | IL15 | Interleukin-15; Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA (By similarity). In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation (By similarity); Belongs to the IL-15/IL-21 family. (162 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2479 aa) |
| | ZBTB7B | Uncharacterized protein. (540 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (340 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (933 aa) |
| | KMT5C | Lysine methyltransferase 5C. (614 aa) |
| | MORN5 | MORN repeat containing 5. (184 aa) |
| | HSPD1 | Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (679 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1977 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1038 aa) |
| | M3X4T8_FELCA | Ig-like domain-containing protein. (114 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (357 aa) |
| | LOC101082108 | Ig-like domain-containing protein. (386 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (233 aa) |
| | FOXO3 | Forkhead box O3. (672 aa) |
| | TLR4 | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (870 aa) |
| | M3XAZ9_FELCA | Ig-like domain-containing protein. (64 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | ENSFCAP00000025816 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (145 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (359 aa) |
| | TNFSF14 | Tumor necrosis factor ligand 1D; Belongs to the tumor necrosis factor family. (242 aa) |
| | ENSFCAP00000026980 | Ig-like domain-containing protein. (196 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | BMI1 | Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ub [...] (326 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (192 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2101 aa) |
| | ENSFCAP00000027729 | Ig-like domain-containing protein. (125 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (280 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | EXOSC3 | Exosome component 3. (450 aa) |
| | ENSFCAP00000030239 | Uncharacterized protein. (145 aa) |
| | ENSFCAP00000030418 | KH type-2 domain-containing protein. (147 aa) |
| | MEF2C | MADS-box domain-containing protein. (483 aa) |
| | IGFBP2 | Insulin like growth factor binding protein 2. (330 aa) |
| | ENSFCAP00000031202 | Uncharacterized protein. (94 aa) |
| | BLOC1S3 | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (198 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (250 aa) |
| | CD83 | CD83 molecule. (391 aa) |
| | HLX | H2.0 like homeobox. (569 aa) |
| | IL7 | Interleukin 7. (158 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (222 aa) |
| | CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (260 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (167 aa) |
| | IGF2 | Insulin like growth factor 2. (280 aa) |
| | TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity); Belongs to the [...] (789 aa) |
| | AP1G1 | AP-1 complex subunit gamma. (829 aa) |
| | SLC26A3-2 | Ig-like domain-containing protein; Belongs to the MHC class II family. (254 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1163 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (553 aa) |
| | AXL | AXL receptor tyrosine kinase. (861 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4108 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (308 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | SH3KBP1 | SH3 domain containing kinase binding protein 1. (720 aa) |
| | BST1 | Bone marrow stromal cell antigen 1. (313 aa) |
| | DPP4 | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] (765 aa) |
| | LOC101082653 | Ig-like domain-containing protein. (276 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (655 aa) |
| | TLR9 | Toll-like receptor 9; Key component of innate and adaptive immunity. TLRs (Toll- like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine- phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity). (1031 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (872 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | NCK1 | Cytoplasmic protein. (455 aa) |
| | ENSFCAP00000039745 | Uncharacterized protein. (55 aa) |
| | SOX12 | Transcription factor SOX. (314 aa) |
| | ENSFCAP00000040186 | Ig-like domain-containing protein. (290 aa) |
| | ENSFCAP00000040280 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (127 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (558 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2420 aa) |
| | LOC101084962 | Ig-like domain-containing protein. (253 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (715 aa) |
| | LOC101090265 | Ig-like domain-containing protein. (263 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (378 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (282 aa) |
| | XBP1 | X-box binding protein 1. (383 aa) |
| | ENSFCAP00000041710 | Ig-like domain-containing protein. (255 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | BLOC1S6 | Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1179 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | FOXP3 | Forkhead box P3. (501 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | ENSFCAP00000044297 | Uncharacterized protein. (546 aa) |
| | CD320 | CD320 molecule. (225 aa) |
| | LOC111558970 | Ig-like domain-containing protein; Belongs to the MHC class II family. (254 aa) |
| | ENSFCAP00000045029 | Ig-like domain-containing protein. (605 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (215 aa) |
| | LOC101082906 | Ig-like domain-containing protein. (282 aa) |
| | LOC111560445 | Ig-like domain-containing protein; Belongs to the MHC class II family. (267 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (916 aa) |
| | CBFB | Uncharacterized protein. (187 aa) |
| | EFNB3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (340 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (351 aa) |
| | SHB | SH2 domain-containing protein. (508 aa) |
| | LOC101090771 | Ig-like domain-containing protein; Belongs to the MHC class II family. (257 aa) |
| | BAD | BCL2 associated agonist of cell death. (273 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (203 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (803 aa) |
| | LOC101081130 | AIG1-type G domain-containing protein. (309 aa) |
| | CD38 | CD38 molecule. (307 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (415 aa) |
| | EXOSC6 | Exosome component 6. (272 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (390 aa) |
| | PCID2 | PCI domain containing 2. (399 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (796 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (280 aa) |
| | LOC111560444 | Ig-like domain-containing protein; Belongs to the MHC class II family. (250 aa) |
| | LOC101084108 | Ig-like domain-containing protein; Belongs to the MHC class II family. (344 aa) |
| | ENSFCAP00000052528 | Uncharacterized protein. (499 aa) |
| | ENSFCAP00000052659 | Uncharacterized protein. (184 aa) |
| | ENSFCAP00000052666 | Uncharacterized protein. (502 aa) |
| | TYROBP | TYRO protein tyrosine kinase binding protein. (137 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (956 aa) |
| | LOC101085539 | Uncharacterized protein. (440 aa) |
| | LOC111560440 | Ig-like domain-containing protein. (287 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (364 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | PRKCZ | Protein kinase C zeta. (649 aa) |
| | FCHO1 | FCH domain only 1. (1023 aa) |
| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | SHLD2 | Shieldin complex subunit 2. (1045 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (877 aa) |
| | ENSFCAP00000055620 | Uncharacterized protein. (580 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) |
| | FECA-DRB | Ig-like domain-containing protein. (344 aa) |
| | CD160 | CD160 molecule. (221 aa) |
| | LOC111556176 | Ig-like domain-containing protein. (285 aa) |
| | LOC101086051 | Ig-like domain-containing protein. (159 aa) |
| | ADA | Adenosine deaminase. (431 aa) |
| | HMGB1 | Uncharacterized protein. (233 aa) |
| | TNFSF4 | Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (295 aa) |
| | CLEC7A | C-type lectin domain containing 7A. (250 aa) |
| | ENSFCAP00000058589 | Uncharacterized protein. (93 aa) |
| | CD5 | CD5 molecule. (524 aa) |
| | ZNF335 | Zinc finger protein 335. (1446 aa) |
| | SIRPA | Ig-like domain-containing protein. (287 aa) |
| | LOC111556169 | Ig-like domain-containing protein. (276 aa) |
| | CD86 | B-lymphocyte activation antigen B7-2 (CD86). (332 aa) |
| | LOC111560443 | Ig-like domain-containing protein; Belongs to the MHC class II family. (322 aa) |
| | LOC111556173 | Ig-like domain-containing protein. (308 aa) |
| | AIF1 | Allograft inflammatory factor 1. (157 aa) |
| | ICOS | Inducible T cell costimulator. (247 aa) |
| | ANXA1 | Annexin. (407 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (556 aa) |
| | CCL19 | C-C motif chemokine. (115 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (693 aa) |
| | EFNB1 | Ephrin B1. (427 aa) |
| | CD27 | CD27 molecule. (296 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (801 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (673 aa) |
