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| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | HHEX | Hematopoietically expressed homeobox. (270 aa) |
| | CBL | Cbl proto-oncogene. (902 aa) |
| | FABP4 | Fatty acid binding protein 4; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa) |
| | BUB3 | BUB3 mitotic checkpoint protein. (328 aa) |
| | DNAJC3 | DnaJ heat shock protein family (Hsp40) member C3. (504 aa) |
| | MSTN | Myostatin. (375 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | CDK5RAP1 | CDK5 regulatory subunit associated protein 1. (583 aa) |
| | DUSP10 | Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (477 aa) |
| | HEG1 | Heart development protein with EGF like domains 1. (1374 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (283 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (362 aa) |
| | SORL1 | Sortilin related receptor 1. (2211 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (234 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (604 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (443 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (641 aa) |
| | DTNBP1 | Dystrobrevin binding protein 1. (336 aa) |
| | DEPTOR | DEP domain containing MTOR interacting protein. (411 aa) |
| | WARS1 | Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (482 aa) |
| | FBXO7 | F-box protein 7. (444 aa) |
| | CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (504 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1139 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (167 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (700 aa) |
| | RASIP1 | Ras interacting protein 1. (943 aa) |
| | EPHA1 | EPH receptor A1. (976 aa) |
| | AJUBA | Ajuba LIM protein. (548 aa) |
| | HEXIM1 | HEXIM P-TEFb complex subunit 1. (359 aa) |
| | ABL1 | Tyrosine-protein kinase. (1150 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | PTPRJ | Protein tyrosine phosphatase receptor type J. (1213 aa) |
| | PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (312 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (834 aa) |
| | ERRFI1 | ERBB receptor feedback inhibitor 1. (460 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (615 aa) |
| | NF2 | Neurofibromin 2. (596 aa) |
| | PTPN1 | Tyrosine-protein phosphatase non-receptor type. (427 aa) |
| | SPRY4 | Sprouty RTK signaling antagonist 4. (321 aa) |
| | SH2B3 | SH2B adaptor protein 3. (578 aa) |
| | RACK1 | WD_REPEATS_REGION domain-containing protein. (424 aa) |
| | RTRAF | Uncharacterized protein. (244 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | NUP62CL | Nsp1_C domain-containing protein. (215 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (558 aa) |
| | PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1. (311 aa) |
| | ZGPAT | Uncharacterized protein. (802 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (738 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa) |
| | LIMK1 | LIM domain kinase 1. (763 aa) |
| | GSKIP | GSK3B interacting protein. (139 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) |
| | RUBCN | Rubicon autophagy regulator. (1014 aa) |
| | ENSFCAP00000036500 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (148 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (400 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (357 aa) |
| | COX11 | Cytochrome c oxidase copper chaperone COX11. (275 aa) |
| | GGNBP2 | Gametogenetin binding protein 2. (740 aa) |
| | APC | APC regulator of WNT signaling pathway. (2874 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (538 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (385 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha; Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). (165 aa) |
| | TFAP4 | Transcription factor AP-4. (337 aa) |
| | LOC101088701 | Ig-like domain-containing protein. (370 aa) |
| | SRC | Tyrosine-protein kinase. (678 aa) |
| | DBNDD2 | Dysbindin domain containing 2. (111 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | PKIG | cAMP-dependent protein kinase inhibitor gamma. (123 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (462 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | BAG2 | BCL2 associated athanogene 2. (211 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (416 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (264 aa) |
| | PTPRQ | Protein tyrosine phosphatase receptor type Q. (2332 aa) |
| | USP44 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (711 aa) |
| | PPM1E | Protein phosphatase, Mg2+/Mn2+ dependent 1E. (754 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B; Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry. (198 aa) |
| | DBNDD1 | Dysbindin domain containing 1. (158 aa) |
| | TMEM130 | Transmembrane protein 130. (475 aa) |
| | PRKAR2A | Protein kinase cAMP-dependent type II regulatory subunit alpha. (401 aa) |
| | SH3BP5L | SH3 binding domain protein 5 like. (393 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (518 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | SHB | SH2 domain-containing protein. (508 aa) |
| | ZFP36 | ZFP36 ring finger protein. (513 aa) |
| | MIDN | Midnolin. (510 aa) |
| | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha. (569 aa) |
| | MYOCD | Myocardin. (962 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | LAX1 | Lymphocyte transmembrane adaptor 1. (402 aa) |
| | BMP4 | Bone morphogenetic protein 4. (409 aa) |
| | TSG101 | Tumor susceptibility 101. (400 aa) |
| | LOC111559734 | Bone morphogenetic protein 7. (426 aa) |
| | INCA1 | Inhibitor of CDK, cyclin A1 interacting protein 1. (256 aa) |
| | FGFR1OP | FGFR1 oncogene partner. (732 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (263 aa) |
| | RGS14 | Regulator of G protein signaling 14. (607 aa) |
| | LOC101101103 | Uncharacterized protein. (1668 aa) |
| | ENSFCAP00000054025 | Uncharacterized protein. (329 aa) |
| | CAMK2N1 | Calcium/calmodulin dependent protein kinase II inhibitor 1. (608 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (899 aa) |
| | ENSFCAP00000055090 | Uncharacterized protein. (94 aa) |
| | NF1 | Neurofibromin 1. (2856 aa) |
| | ZFYVE28 | Zinc finger FYVE-type containing 28. (961 aa) |
| | ENSFCAP00000056238 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (185 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1299 aa) |
| | PPIA | Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (200 aa) |
| | CEP85 | Centrosomal protein 85. (882 aa) |
| | ADAR | Adenosine deaminase RNA specific. (995 aa) |
| | BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B. (1062 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (804 aa) |
| | PRDX3 | Peroxiredoxin 3. (270 aa) |
| | SH3BP5 | SH3 domain binding protein 5. (451 aa) |
| | INPP5K | Inositol polyphosphate-5-phosphatase K. (525 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (1095 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (435 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (551 aa) |
| | WNK4 | WNK lysine deficient protein kinase 4. (1322 aa) |
| | ENSFCAP00000061110 | TGF_BETA_2 domain-containing protein. (362 aa) |
| | DAB2IP | DAB2 interacting protein. (1166 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | DEFB114 | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (68 aa) |
| | PKIA | cAMP-dependent protein kinase inhibitor alpha. (120 aa) |
| | CAV1 | Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa) |
| | PKN1 | Protein kinase N1. (1064 aa) |
| | FAM72A | Uncharacterized protein. (149 aa) |
| | QARS1 | Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (775 aa) |
| | SOCS4 | Suppressor of cytokine signaling 4. (441 aa) |
| | ENSFCAP00000030321 | Uncharacterized protein. (79 aa) |
| | AKT1S1 | AKT1 substrate 1. (276 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (196 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | VPS25 | Vacuolar protein sorting 25 homolog. (176 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | ITGB1BP1 | Integrin subunit beta 1 binding protein 1. (213 aa) |
| | ENSFCAP00000031558 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (163 aa) |
| | SMYD3 | SET and MYND domain containing 3. (428 aa) |
| | MAD2L1 | Mitotic arrest deficient 2 like 1. (221 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (421 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (302 aa) |
| | PRKAR2B | Protein kinase cAMP-dependent type II regulatory subunit beta. (618 aa) |
| | DUSP16 | Dual specificity phosphatase 16. (663 aa) |
| | PTPRB | Protein tyrosine phosphatase receptor type B. (2215 aa) |
| | ENSFCAP00000028212 | Uncharacterized protein. (83 aa) |
| | SIRT1 | Sirtuin 1. (745 aa) |
| | SRCIN1 | SRC kinase signaling inhibitor 1. (1219 aa) |
| | CBLB | Cbl proto-oncogene B. (1182 aa) |
| | CBLC | Cbl proto-oncogene C. (494 aa) |
| | CORO1C | Coronin; Belongs to the WD repeat coronin family. (525 aa) |
| | BAG5 | BCL2 associated athanogene 5. (447 aa) |
| | LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1620 aa) |
| | UBASH3B | Ubiquitin associated and SH3 domain containing B. (649 aa) |
| | SMCR8 | SMCR8-C9orf72 complex subunit. (938 aa) |
| | RB1 | RB transcriptional corepressor 1. (930 aa) |
| | SPRY3 | Sprouty RTK signaling antagonist 3. (288 aa) |
| | M3XB87_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (160 aa) |
| | MVP | Major vault protein. (892 aa) |
| | HEXIM2 | HEXIM P-TEFb complex subunit 2. (292 aa) |
| | PRKAR1B | Protein kinase cAMP-dependent type I regulatory subunit beta. (378 aa) |
| | M3X892_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (144 aa) |
| | PAQR3 | Progestin and adipoQ receptor family member 3. (311 aa) |
| | PHPT1 | Phosphohistidine phosphatase 1. (125 aa) |
| | IBTK | Inhibitor of Bruton tyrosine kinase. (1311 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (547 aa) |
| | GSK3A | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (483 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1127 aa) |
| | LOC101082108 | Ig-like domain-containing protein. (386 aa) |
| | LYN | Tyrosine-protein kinase. (526 aa) |
| | TRIM27 | Tripartite motif containing 27. (513 aa) |
| | POT1 | Protection of telomeres 1. (785 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (619 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1; May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage (By similarity). Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression (By similarity). Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1 (By similarity). At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity). Inhibits [...] (164 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | M3X052_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (158 aa) |
| | TESK1 | Testis associated actin remodelling kinase 1. (628 aa) |
| | M3WY96_FELCA | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa) |
